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Fletta eftir höfundi "b27bb955-5ca1-438f-9afb-9c67e4dab932"

Fletta eftir höfundi "b27bb955-5ca1-438f-9afb-9c67e4dab932"

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    Age and Influenza-Specific Pre-Vaccination Antibodies Strongly Affect Influenza Vaccine Responses in the Icelandic Population whereas Disease and Medication Have Small Effects 
    Ólafsdóttir, Þórunn Ásta; Alexandersson, Kristján F.; Sveinbjornsson, Gardar; Lapini, Giulia; Palladino, Laura; Montomoli, Emanuele; Del Giudice, Giuseppe; Gudbjartsson, Daniel; Jonsdottir, Ingileif (Frontiers Media SA, 2018-01-08)
    Influenza vaccination remains the best strategy for the prevention of influenza virus-related disease and reduction of disease severity and mortality. However, there is large individual variation in influenza vaccine responses. In this study, we ...
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    Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis 
    Ólafsdóttir, Þórunn Ásta; Theódórs, Fannar; Bjarnadóttir, Kristbjörg; Björnsdóttir, Unnur Steina; Agustsdottir, Arna B.; Stefánsson, Ólafur A.; Ivarsdottir, Erna; Sigurðsson, Jón K.; Benónísdóttir, Stefanía; Eyjólfsson, Guðmundur I.; Gíslason, Davíð; Gislason, Thorarinn; Guðmundsdóttir, Steinunn; Gylfason, Arnaldur; Halldórsson, Bjarni; Halldorsson, Gisli; Júlíusdóttir, Þórhildur; Kristinsdottir, Anna M.; Lúðvíksdóttir, Dóra; Ludviksson, Bjorn; Másson, Gísli; Norland, Kristjan; Onundarson, Pall; Olafsson, Isleifur; Sigurdardottir, Olof; Stefánsdóttir, Lilja; Sveinbjörnsson, Garðar; Tragante do O, Vinicius; Gudbjartsson, Daniel; Þorleifsson, Guðmar; sulem, patrick; Thorsteinsdottir, Unnur; Norddahl, Guðmundur L.; Jonsdottir, Ingileif; Stefansson, Kari (Springer Science and Business Media LLC, 2020-01-20)
    Asthma is one of the most common chronic diseases affecting both children and adults. We report a genome-wide association meta-analysis of 69,189 cases and 702,199 controls from Iceland and UK biobank. We find 88 asthma risk variants at 56 loci, 19 ...
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    Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis 
    Stacey, Simon N.; Zink, Florian; Halldórsson, Gísli Hreinn; Stefánsdóttir, Lilja; Guðjónsson, Sigurjón Axel; Einarsson, Gudmundur; Hjörleifsson, Grimur; Eiríksdóttir, Þjóðbjörg; Helgadottir, Anna; Björnsdottir, Gyda; Thorgeirsson, Thorgeir E.; Ólafsdóttir, Þórunn Ásta; Jónsdóttir, Ingileif; Gretarsdottir, Solveig; Tragante, Vinicius; Magnússon, Magnús Karl; Jonsson, Hakon; Gudmundsson, Julius; Olafsson, Sigurgeir; Holm, Hilma; Gudbjartsson, Daniel F.; Sulem, Patrick; Helgason, Agnar Sturla; Þorsteinsdóttir, Unnur; Tryggvadottir, Laufey; Rafnar, Thorunn; Melsted, Páll; Úlfarsson, Magnús Örn; Viðarsson, Brynjar; Thorleifsson, Gudmar; Stefánsson, Kári (2023-12)
    Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cells is derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of 45,510 Icelandic and 130,709 UK Biobank participants combined with a mutational ...