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Browsing by Author "Pedersen, O.B."

Browsing by Author "Pedersen, O.B."

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    Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset 
    Saevarsdottir, S.; Stefansdottir, L.; Sulem, P.; Thorleifsson, G.; Ferkingstad, E.; Rutsdottir, G.; Glintborg, B.; Westerlind, H.; Grondal, G.; Loft, I.C.; Sorensen, S.B.; Lie, B.A.; Brink, M.; Arlestig, L.; Arnthorsson, A.O.; Baecklund, E.; Banasik, K.; Bank, S.; Bjorkman, L.I.; Ellingsen, T.; Erikstrup, C.; Frei, O.; Gjertsson, I.; Gudbjartsson, D.F.; Gudjonsson, S.A.; Halldorsson, G.H.; Hendricks, O.; Hillert, J.; Hogdall, E.; Jacobsen, Sø; Jensen, D.V.; Jonsson, H.; Kastbom, A.; Kockum, I.; Kristensen, S.; Kristjansdottir, H.; Larsen, M.H.; Linauskas, A.; Hauge, E.-M.; Loft, A.G.; Ludviksson, B.R.; Lund, S.H.; Markusson, T.; Masson, G.; Melsted, P.; Moore, K.H.S.; Munk, H.; Nielsen, K.R.; Norddahl, G.L.; Oddsson, A.; Olafsdottir, T.A.; Olason, P.I.; Olsson, T.; Ostrowski, S.R.; Hørslev-Petersen, K.; Rognvaldsson, S.; Sanner, H.; Silberberg, G.N.; Stefansson, H.; Sørensen, E.; Sørensen, I.J.; Turesson, C.; Bergman, T.; Alfredsson, L.; Kvien, T.K.; Brunak, Sø; Steinsson, K.; Andersen, V.; Andreassen, O.A.; Rantapää-Dahlqvist, S.; Hetland, M.L.; Klareskog, L.; Askling, J.; Padyukov, L.; Pedersen, O.B.V.; Thorsteinsdottir, U.; Jonsdottir, I.; Stefansson, K.; Saevarsdottir, S.; Markússon, Þorsteinn (2022-04-25)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...
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    Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology 
    Nielsen, K.R.; Pedersen, O.B.; Sørensen, E.; Ostrowski, S.; Johansson, P.I.; Gudbjartsson, D.; Stefansson, H.; Larsen, M.A.H.; Didriksen, M.; Sækmose, S.; Zeggini, E.; Hatzikotoulas, K.; Southam, L.; Gilly, A.; Barysenka, A.; van Meurs, J.B.J.; Boer, C.G.; Uitterlinden, A.G.; Styrkársdóttir, U.; Stefánsdóttir, L.; Esko, T.; Mägi, R.; Teder-Laving, M.; Ikegawa, S.; Terao, C.; Takuwa, H.; Meulenbelt, I.; Coutinho de Almeida, R.; Kloppenburg, M.; Tuerlings, M.; Slagboom, P.E.; Nelissen, R.R.G.H.H.; Valdes, A.M.; Mangino, M.; Tsezou, A.; Zengini, E.; Alexiadis, G.; Babis, G.C.; Cheah, K.S.E.; Wu, T.T.; Samartzis, D.; Cheung, J.P.Y.; Sham, P.C.; Kraft, P.; Kang, J.H.; Hveem, K.; Zwart, J.-A.; Luetge, A.; Skogholt, A.H.; Johnsen, M.B.; Thomas, L.F.; Winsvold, B.; Gabrielsen, M.E.; Lee, M.T.M.; Zhang, Y.; Lietman, S.A.; Shivakumar, M.; Smith, G.D.; Tobias, J.H.; Hartley, A.; Gaunt, T.R.; Zheng, J.; Wilkinson, J.M.; Steinberg, J.; Morris, A.P.; Ulfarsson, E.; Blondal, J.; Brunak, S.; Ostrowski, S.R.; Ullum, H.; Þorsteinsdóttir, U.; Stefansson, H.; Gudbjartsson, D.F.; Thorgeirsson, T.E.; Stefansson, K.; DBDS Genetic Consortium; GO Consortium (2022-02-02)
    Back pain is a common and debilitating disorder with largely unknown underlying biology. Here we report a genome-wide association study of back pain using diagnoses assigned in clinical practice; dorsalgia (119,100 cases, 909,847 controls) and ...