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Browsing by Author "Porsbjerg, Celeste"

Browsing by Author "Porsbjerg, Celeste"

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    Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults 
    Porsbjerg, Celeste; Ulrik, Charlotte; Skjold, Tina; Backer, Vibeke; Laerum, Birger; Lehman, Sverre; Janson, Crister; Sandstrøm, Thomas; Bjermer, Leif; Dahlen, Barbro; Lundbäck, Bo; Ludviksdottir, Dora; Björnsdóttir, Unnur; Altraja, Alan; Lehtimäki, Lauri; Kauppi, Paula; Karjalainen, Jussi; Kankaanranta, Hannu (Informa UK Limited, 2018-01)
    Although a minority of asthma patients suffer from severe asthma, they represent a major clinical challenge in terms of poor symptom control despite high-dose treatment, risk of exacerbations, and side effects. Novel biological treatments may benefit ...
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    A partial loss-of-function variant in STAT6 protects against type 2 asthma 
    Kristjansdottir, Katla; Norddahl, Gudmundur L; Ivarsdottir, Erna V; Halldórsson, Gísli Hreinn; Einarsson, Gudmundur; Bjarnadottir, Kristbjorg; Rutsdottir, Gudrun; Arnthorsson, Asgeir O; Erikstrup, Christian; Gudmundsdottir, Steinunn; Gunnarsdottir, Kristbjorg; Gunnbjörnsdóttir, María I; Halldórsson, Bjarni Vilhjálmur; Holm, Hilma; Lúðvíksdóttir, Dóra; Lúðvíksson, Björn Rúnar; Brunak, Søren; Bruun, Mie Topholm; Mikkelsen, Christina; Mikkelsen, Susan; Jensen, Bitten Aagaard; Sørensen, Erik; Thomsen, Simon Francis; Ullum, Henrik; Ólafsson, Ísleifur; Önundarson, Páll Torfi; Ostrowski, Sisse Rye; Sævarsdóttir, Sædís; Sigurdardottir, Olof; Sigurgeirsson, Bardur; Snaebjarnarson, Audunn S; Sveinbjornsson, Gardar; Thorlacius, Gudny E; Thorleifsson, Gudmar; Tragante, Vinicius; Vidarsson, Brynjar; Porsbjerg, Celeste; Björnsdóttir, Unnur Steina; Sulem, Patrick; Gudbjartsson, Daniel F; Melsted, Páll; Pedersen, Ole Bv; Jónsdóttir, Ingileif; Olafsdottir, Thorunn A; Stefánsson, Kári (2025-01)
    BACKGROUND: Signal transducer and activator of transcription 6 (STAT6) is central to type 2 (T2) inflammation, and common noncoding variants at the STAT6 locus associate with various T2 inflammatory traits, including diseases, and its pathway is widely ...
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    Prevalence and management of severe asthma in the Nordic countries : findings from the NORDSTAR cohort 
    Hansen, Susanne; von Bülow, Anna; Sandin, Patrik; Ernstsson, Olivia; Janson, Christer; Lehtimäki, Lauri; Kankaanranta, Hannu; Ulrik, Charlotte; Aarli, Bernt Bøgvald; Fues Wahl, Hanna; Geale, Kirk; Tang, Sheila Tuyet; Wolf, Maija; Larsen, Tom; Altraja, Alan; Backman, Helena; Kilpeläinen, Maritta; Viinanen, Arja; Lúðvíksdóttir, Dóra; Kauppi, Paula; Sverrild, Asger; Lehmann, Sverre; Backer, Vibeke; Yasinska, Valentyna; Skjold, Tina; Karjalainen, Jussi; Bossios, Apostolos; Porsbjerg, Celeste (2023-03-01)
    BACKGROUND: Real-life evidence on prevalence and management of severe asthma is limited. Nationwide population registries across the Nordic countries provide unique opportunities to describe prevalence and management patterns of severe asthma at ...
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    A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma 
    Smith, Dirk; Helgason, Hannes; sulem, patrick; Björnsdóttir, Unnur Steina; Lim, Ai Ching; Sveinbjornsson, Gardar; Hasegawa, Haruki; Brown, Michael; Ketchem, Randal R.; Gavala, Monica; Garrett, Logan; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Sigurðsson, Ásgeir; Magnússon, Ólafur T.; Eyjólfsson, Guðmundur I.; Ólafsson, Ísleifur; Önundarson, Páll Torfi; Sigurðardóttir, Ólöf; Gíslason, Davíð; Gislason, Thorarinn; Ludviksson, Bjorn; Lúðvíksdóttir, Dóra; Boezen, H. Marike; Heinzmann, Andrea; Krueger, Marcus; Porsbjerg, Celeste; Ahluwalia, Tarunveer S.; Waage, Johannes; Backer, Vibeke; Deichmann, Klaus A.; Koppelman, Gerard H.; Bønnelykke, Klaus; Bisgaard, Hans; Másson, Gísli; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Johnston, James A.; Jonsdottir, Ingileif; Stefansson, Kari (Public Library of Science (PLoS), 2017-03-08)
    IL-33 is a tissue-derived cytokine that induces and amplifies eosinophilic inflammation and has emerged as a promising new drug target for asthma and allergic disease. Common variants at IL33 and IL1RL1, encoding the IL-33 receptor ST2, associate with ...