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Browsing by Author "Rögnvaldsson, Sæmundur"

Browsing by Author "Rögnvaldsson, Sæmundur"

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    Allir geta smitast af HIV en enginn ætti að fá alnæmi : Tvö tilfelli alnæmis hjá íslenskum konum 
    Hólmgrímsdóttir, Katrín; Rögnvaldsson, Sæmundur; Ragnarsdóttir, Telma Huld; Kojic, Erna Milunka (2024-11)
    HIV getur haft margvíslegar birtingarmyndir og án meðferðar getur það leitt til alnæmis og alvarlegara fylgikvilla. Við eigum öflug lyf við sjúkdómnum og viljum meðhöndla alla með HIV áður en kemur til alvarlegs sjúkdómsástands en forsenda þess er að ...
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    Analysis of smoldering multiple myeloma according to the target of the monoclonal immunoglobulin of patients 
    Hermouet, Sylvie; Mennesson, Nicolas; Allain-Maillet, Sophie; Bigot-Corbel, Edith; Olafsson, Andri; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Eyþórsson, Elías Sæbjörn; Jónsson, Ásbjörn; Löve, Þorvarður Jón; Rögnvaldsson, Sæmundur; Björnsson, Einar Stefán; Thorsteinsdóttir, Sigrún; Kristinsson, Sigurður Yngvi (2024-12)
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    Correction : Iceland screens, treats, or prevents multiple myeloma (iStopMM): a population-based screening study for monoclonal gammopathy of undetermined significance and randomized controlled trial of follow-up strategies (Blood Cancer Journal, (2021), 11, 5, (94), 10.1038/s41408-021-00480-w) 
    Rögnvaldsson, Sæmundur; Löve, Þorvarður Jón; Þorsteinsdóttir, Sigrún; Reed, Elín Ruth; Óskarsson, Jón Þórir; Pétursdóttir, Íris; Sigurðardóttir, Guðrún Ásta; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Þórðardóttir, Ásdís Rósa; Eyþórsson, Elías Sæbjörn; Jónsson, Ásbjörn; Björnsson, Andri Steinþór; Gunnarsson, Gunnar Þór; Pálsson, Runólfur; Indriðason, Ólafur Skúli; Gíslason, Gauti Kjartan; Ólafsson, Andri; Hákonardóttir, Guðlaug Katrín; Brinkhuis, Manje; Halldórsdóttir, Sara Lovísa; Ásgeirsdóttir, Tinna Laufey; Steingrímsdóttir, Hlíf; Danielsen, Ragnar; Wessman, Inga Dröfn; Kampanis, Petros; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2023-03-20)
    In this article the author name Malin Hultcrantz was incorrectly written as Malin Hulcrantz. The original article has been corrected.
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    Deciphering the genetics and mechanisms of predisposition to multiple myeloma 
    Went, Molly; Duran-Lozano, Laura; Halldorsson, Gisli H.; Gunnell, Andrea; Ugidos-Damboriena, Nerea; Law, Philip; Ekdahl, Ludvig; Sud, Amit; Thorleifsson, Gudmar; Thodberg, Malte; Ólafsdóttir, Þórunn Ásta; Lamarca-Arrizabalaga, Antton; Cafaro, Caterina; Niroula, Abhishek; Ajore, Ram; Lopez de Lapuente Portilla, Aitzkoa; Ali, Zain; Pertesi, Maroulio; Goldschmidt, Hartmut; Stefansdottir, Lilja; Kristinsson, Sigurður Yngvi; Stacey, Simon N.; Löve, Þorvarður Jón; Rögnvaldsson, Sæmundur; Hajek, Roman; Vodicka, Pavel; Pettersson-Kymmer, Ulrika; Späth, Florentin; Schinke, Carolina; Van Rhee, Frits; Sulem, Patrick; Ferkingstad, Egil; Hjorleifsson Eldjarn, Grimur; Mellqvist, Ulf Henrik; Jonsdottir, Ingileif; Morgan, Gareth; Sonneveld, Pieter; Waage, Anders; Weinhold, Niels; Thomsen, Hauke; Försti, Asta; Hansson, Markus; Juul-Vangsted, Annette; Thorsteinsdottir, Unnur; Hemminki, Kari; Kaiser, Martin; Rafnar, Thorunn; Stefansson, Kari; Houlston, Richard; Nilsson, Björn (2024-08-05)
    Multiple myeloma (MM) is an incurable malignancy of plasma cells. Epidemiological studies indicate a substantial heritable component, but the underlying mechanisms remain unclear. Here, in a genome-wide association study totaling 10,906 cases and 366,221 ...
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    Defining new reference intervals for serum free light chains in individuals with chronic kidney disease : Results of the iStopMM study 
    Long, Þórir Einarsson; Indriðason, Ólafur Skúli; Pálsson, Runólfur; Rögnvaldsson, Sæmundur; Löve, Þorvarður Jón; Thorsteinsdóttir, Sigrún; Sverrisdóttir, Ingigerður S; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Thordardottir, Asdis Rosa; Eyþórsson, Elías Sæbjörn; Jónsson, Ásbjörn; Gíslason, Gauti Kjartan; Ólafsson, Andri; Steingrímsdóttir, Hlíf; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2022-09-14)
    Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-based cohort, we aimed to establish a reference interval for FLCs in persons with chronic kidney disease (CKD). A total of 75422 ...
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    Determining hemodilution in diagnostic bone marrow aspirated samples in plasma cell disorders by next-generation flow cytometry : Proposal for a bone marrow quality index 
    Óskarsson, Jón Þórir; Rögnvaldsson, Sæmundur; Thorsteinsdottir, Sigrun; Aspelund, Thor; Gunnarsson, Steinar Bragi; Hákonardóttir, Guðlaug Katrín; Sigurðardóttir, Guðrún Ásta; Þórðardóttir, Ásdís Rósa; Gíslason, Gauti Kjartan; Ólafsson, Andri; Sigurðsson, Jón Kristinn; Eyþórsson, Elías; Jónsson, Ásbjörn; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni A.; Pálmason, Róbert; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Harding, Stephen; Flores-Montero, Juan; Orfao, Alberto; Durie, Brian G.M.; Love, Thorvardur Jon; Kristinsson, Sigurdur Yngvi (2023-12-01)
    Hemodilution of bone marrow (BM) aspirates is a limitation of multiparameter flow cytometry (MFC) in plasma cell disorders. There is a need for a validated approach for assessing sample quality and the distribution of non-plasma cell BM populations by ...
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    Diabetes mellitus and risk of plasma cell and lymphoproliferative disorders in 94,579 cases and 368,348 matched controls 
    Shah, Urvi A.; Rögnvaldsson, Sæmundur; Derkach, Andriy; Björkholm, Magnus; Turesson, Ingemar; David, Yael; Hultcrantz, Malin; Tan, Carlyn; Hassoun, Hani; Korde, Neha; Lesokhin, Alexander; Mailankody, Sham; Kristinsson, Sigurður Yngvi; Ola Landgren, C. (2022-01-01)
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    Disease associations with monoclonal gammopathy of undetermined significance can only be evaluated using screened cohorts : results from the population-based iStopMM study 
    Sigurbergsdóttir, Aðalbjörg Ýr; Rögnvaldsson, Sæmundur; Thorsteinsdóttir, Sigrún; Sverrisdóttir, Ingigerður; Sigurðardóttir, Guðrún Ásta; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Þórðardóttir, Ásdís Rósa; Gíslason, Gauti Kjartan; Ólafsson, Andri; Hultcrantz, Malin; Durie, Brian G M; Harding, Stephen; Landgren, Ola; Löve, Þorvarður Jón; Kristinsson, Sigurður Yngvi (2023-12-01)
    Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor condition that precedes multiple myeloma and related disorders but has also been associated with other medical conditions. Since systematic screening is not recommended, ...
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    Iceland screens, treats, or prevents multiple myeloma (iStopMM) : a population-based screening study for monoclonal gammopathy of undetermined significance and randomized controlled trial of follow-up strategies 
    Rögnvaldsson, Sæmundur; Love, Thorvardur Jon; Thorsteinsdottir, Sigrun; Reed, Elín Ruth; Óskarsson, Jón Þórir; Pétursdóttir, Íris; Sigurðardóttir, Guðrún Ásta; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni A.; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Þórðardóttir, Ásdís Rósa; Eyþórsson, Elías; Jónsson, Ásbjörn; Björnsson, Andri S.; Gunnarsson, Gunnar Þór; Pálsson, Runólfur; Indriðason, Ólafur Skúli; Gíslason, Gauti Kjartan; Ólafsson, Andri; Hákonardóttir, Guðlaug Katrín; Brinkhuis, Manje; Halldórsdóttir, Sara Lovísa; Ásgeirsdóttir, Tinna Laufey; Steingrímsdóttir, Hlíf; Danielsen, Ragnar; Dröfn Wessman, Inga; Kampanis, Petros; Hulcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2021-05-17)
    Monoclonal gammopathy of undetermined significance (MGUS) precedes multiple myeloma (MM). Population-based screening for MGUS could identify candidates for early treatment in MM. Here we describe the Iceland Screens, Treats, or Prevents Multiple Myeloma ...
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    Immunophenotypic assessment of clonal plasma cells and B-cells in bone marrow and blood in the diagnostic classification of early stage monoclonal gammopathies : an iSTOPMM study 
    Pérez-Escurza, Oihane; Flores-Montero, Juan; Óskarsson, Jón Þórir; Sanoja-Flores, Luzalba; del Pozo, Julio; Lecrevisse, Quentin; Martín, Silvia; Reed, Elín Ruth; Hákonardóttir, Guðlaug Katrín; Harding, Stephen; Þorsteinsdóttir, Sigrún; Rögnvaldsson, Sæmundur; Löve, Þorvarður Jón; Durie, Brian; Kristinsson, Sigurður Yngvi; Orfao, Alberto (2023-12-11)
    Monoclonal gammopathy of undetermined significance (MGUS) is the earliest discernible stage of multiple myeloma (MM) and Waldenström’s macroglobulinemia (WM). Early diagnosis of MG may be compromised by the low-level infiltration, undetectable to ...
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    Monoclonal gammopathy of undetermined significance and COVID-19 : a population-based cohort study 
    Rögnvaldsson, Sæmundur; Eythorsson, Elias; Thorsteinsdottir, Sigrun; Vidarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurdardottir, Margret; Thorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Runólfsdóttir, Hrafnhildur L.; Helgason, Dadi; Emilsdóttir, Arna Rut; Ágústsson, Arnar Snær; Björnsson, Aron Hjalti; Kristjánsdóttir, Gudrún; Thordardottir, Asdis Rosa; Indridason, Olafur Skuli; Jónsson, Ásbjörn; Gislason, Gauti Kjartan; Olafsson, Andri; Steingrímsdóttir, Hlíf; Kampanis, Petros; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Palsson, Runolfur; Love, Thorvarður Jon; Kristinsson, Sigurdur Yngvi (2021-12-01)
    Multiple myeloma (MM) patients have increased risk of severe coronavirus disease 2019 (COVID-19) when infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Monoclonal gammopathy of undetermined significance (MGUS), the precursor of ...
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    Monoclonal gammopathy of undetermined significance with multiple paraproteins : A population-based screening study 
    Rögnvaldsson, Sæmundur; Óskarsson, Jón Þórir; Thorsteinsdóttir, Sigrun; Hultcrantz, Malin; Pálmason, Róbert; Sverrisdottir, Ingigerdur S; Eyþórsson, Elías Sæbjörn; Long, Thorir E; Ólafsson, Ísleifur; Þorsteinsdóttir, Ingunn; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Jonsson, Asbjorn; Durie, Brian G M; Harding, Stephen; Landgren, Ola; Löve, Þorvarður Jón; Kristinsson, Sigurður Yngvi (2024-11)
    Monoclonal gammopathy of undetermined significance (MGUS) is the precursor of multiple myeloma (MM) and related disorders. MGUS is characterized by asymptomatic paraproteinemia. In some cases, multiple paraproteins can be identified but the clinical ...
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    Monoclonal gammopathy of what significance?: Overcoming the methodological limitations of studying an asymptomatic precursor disorder 
    Rögnvaldsson, Sæmundur (University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-10-10)
    Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic disorder caused by the accumulation of monoclonal immunoglobulin secreting cells in the bone marrow. The main clinical implication of MGUS is that it’s the precursor of multiple ...
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    Peripheral neuropathy and monoclonal gammopathy of undetermined significance : A population-based study including 15,351 cases and 58,619 matched controls 
    Rögnvaldsson, Sæmundur; Steingrímsson, Vilhjálmur; Turesson, Ingemar; Björkholm, Magnus; Landgren, Ola; Kristinsson, Sigurður Yngvi (2020-11)
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    The significance of free light-chain ratio in light-chain monoclonal gammopathy of undetermined significance : a flow cytometry sub-study of the iStopMM screening study 
    Óskarsson, Jón Þórir; Rögnvaldsson, Sæmundur; Thorsteinsdottir, Sigrun; Long, Þórir Einarsson; Ólafsson, Andri; Eyþórsson, Elías Sæbjörn; Jónsson, Ásbjörn; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Pálmason, Róbert; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Harding, Stephen J.; Durie, Brian G.M.; Löve, Þorvarður Jón; Kristinsson, Sigurður Yngvi (2024-12-18)
    Light-chain (LC) monoclonal gammopathy of undetermined significance (MGUS) is a precursor of multiple myeloma (MM) and related conditions. LC-MGUS is characterized by free light-chain (FLC) levels outside defined reference intervals, indirectly indicating ...