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Fletta eftir höfundi "Yang, Laurence"

Fletta eftir höfundi "Yang, Laurence"

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    Restoration of fitness lost due to dysregulation of the pyruvate dehydrogenase complex is triggered by ribosomal binding site modifications 
    Anand, Amitesh; Olson, Connor A.; Sastry, Anand V.; Patel, Arjun; Szubin, Richard; Yang, Laurence; Feist, Adam M.; Pálsson, Bernhard Örn (2021-04-01)
    Pyruvate dehydrogenase complex (PDC) functions as the main determinant of the respiro-fermentative balance because it converts pyruvate to acetyl-coenzyme A (CoA), which then enters the TCA (tricarboxylic acid cycle). PDC is repressed by the pyruvate ...
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    Visualizing metabolic network dynamics through time-series metabolomic data 
    Buchweitz, Lea F.; Yurkovich, James T.; Blessing, Christoph; Kohler, Veronika; Schwarzkopf, Fabian; King, Zachary A.; Yang, Laurence; Jóhannsson, Freyr; Sigurjónsson, Ólafur E.; Rolfsson, Óttar; Heinrich, Julian; Dräger, Andreas (Springer Science and Business Media LLC, 2020-04-03)
    Background: New technologies have given rise to an abundance of-omics data, particularly metabolomic data. The scale of these data introduces new challenges for the interpretation and extraction of knowledge, requiring the development of innovative ...