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Fletta eftir höfundi "Patton, E. Elizabeth"

Fletta eftir höfundi "Patton, E. Elizabeth"

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    BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export 
    Ngeow, Kao Chin; Friedrichsen, Hans J.; Li, Linxin; Zeng, Zhiqiang; Andrews, Sarah; Volpon, Laurent; Brunsdon, Hannah; Berridge, Georgina; Picaud, Sarah; Fischer, Roman; Lisle, Richard; Knapp, Stefan; Filippakopoulos, Panagis; Knowles, Helen; Steingrimsson, Eirikur; Borden, Katherine L. B.; Patton, E. Elizabeth; Goding, Colin R. (Proceedings of the National Academy of Sciences, 2018-08-27)
    The close integration of the MAPK, PI3K, and WNT signaling pathways underpins much of development and is deregulated in cancer. In principle, combinatorial posttranslational modification of key lineage-specific transcription factors would be an effective ...
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    Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution 
    Louphrasitthiphol, Pakavarin; Siddaway, Robert; Loffreda, Alessia; Pogenberg, Vivian; Friedrichsen, Hans; Schepsky, Alexander; Zeng, Zhiqiang; Lu, Min; Strub, Thomas; Freter, Rasmus; Lisle, Richard; Suer, Eda; Thomas, Benjamin; Schuster-Böckler, Benjamin; Filippakopoulos, Panagis; Middleton, Mark; Lu, Xin; Patton, E. Elizabeth; Davidson, Irwin; Lambert, Jean-Philippe; Wilmanns, Matthias; Steingrimsson, Eirikur; Mazza, Davide; Goding, Colin R. (Elsevier BV, 2020-08-06)
    It is widely assumed that decreasing transcription factor DNA-binding affinity reduces transcription initiation by diminishing occupancy of sequence-specific regulatory elements. However, in vivo transcription factors find their binding sites while ...