Opin vísindi

Fletta eftir höfundi "Sigurðsson, Snævar"

Fletta eftir höfundi "Sigurðsson, Snævar"

Röðun: Raða: Niðurstöður:

  • Icon
    Evaluating Prophylactic Effect of Bovine Colostrum on Intestinal Barrier Function in Zonulin Transgenic Mice : A Transcriptomic Study 
    Ásbjörnsdóttir, Birna Guðrún; Sigurðsson, Snævar; Miranda-Ribera, Alba; Fiorentino, Maria; Konno, Takumi; Lan, Jinggang; Guðmundsson, Lárus Steinþór; Gottfreðsson, Magnús; Lauth, Bertrand Andre Marc; Birgisdóttir, Bryndís Eva; Fasano, Alessio (2023-09-29)
    The intestinal barrier comprises a single layer of epithelial cells tightly joined to form a physical barrier. Disruption or compromise of the intestinal barrier can lead to the inadvertent activation of immune cells, potentially causing an increased ...
  • Icon
    Expression of ncRNAs on the DLK1-DIO3 Locus Is Associated With Basal and Mesenchymal Phenotype in Breast Epithelial Progenitor Cells 
    Budkova, Zuzana; Sigurðardóttir, Anna Karen; Briem, Eiríkur; Bergthorsson, Jon Thor; Sigurðsson, Snævar; Magnusson, Magnus Karl; Traustadottir, Gunnhildur Asta; Gudjonsson, Thorarinn; Hilmarsdóttir, Bylgja (Frontiers Media SA, 2020-06-16)
    Epithelial-to-mesenchymal transition (EMT) and its reversed process mesenchymal-to-epithelial transition (MET) play a critical role in epithelial plasticity during development and cancer progression. Among important regulators of these cellular processes ...
  • Icon
    Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations 
    Ólafsson, Sigurgeir; Stridh, Pernilla; Bos, Steffan Daniël; Ingason, Andrés; Euesden, Jack; sulem, patrick; Thorleifsson, Gudmar; Gústafsson, Ómar; Jóhannesson, Ari; Geirsson, Árni J.; Þórsson, Árni V.; Sigurgeirsson, Bárður; Ludviksson, Bjorn; Ólafsson, Elías; Kristjansdottir, Helga; Jónasson, Jón G.; Ólafsson, Jón Hjaltalín; Örvar, Kjartan B.; Benediktsson, Rafn; Bjarnason, Ragnar Grímur; Kristjánsdóttir, Sjöfn; Gislason, Thorarinn; Valdimarsson, Trausti; Mikaelsdóttir, Evgenía; Sigurðsson, Snævar; Jonsson, Stefan; Rafnar, Thorunn; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Knudsen, Gun Peggy; Celius, Elisabeth G.; Myhr, Kjell-Morten; Gröndal, Gerður; Steinsson, Kristján; Valdimarsson, Helgi; Björnsson, Sigurður; Björnsdóttir, Unnur Steina; Björnsson, Einar Stefán; Nilsson, Bjorn; Andreassen, Ole A.; Alfredsson, Lars; Hillert, Jan; Kockum, Ingrid Skelton; Másson, Gísli; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Stefansson, Hreinn; Hjaltason, Haukur; Harbo, Hanne F.; Olsson, Tomas; Jonsdottir, Ingileif; Stefansson, Kari (Springer Nature, 2017-08-08)
    A meta-analysis of publicly available summary statistics on multiple sclerosis combined with three Nordic multiple sclerosis cohorts (21,079 cases, 371,198 controls) revealed seven sequence variants associating with multiple sclerosis, not reported ...
  • Icon
    A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease 
    Arnadottir, Gudny; Norðdahl, Guðmundur L.; Gudmundsdottir, Steinunn; Ágústsdóttir, Arna B.; Sigurðsson, Snævar; Jensson, Brynjar Örn; Bjarnadóttir, Kristbjörg; Theodórs, Fannar; Benonisdottir, Stefania; Ívarsdóttir, Erna V.; Oddsson, Asmundur; Kristjánsson, Ragnar P.; Sulem, Gerald; Alexandersson, Kristján F.; Júlíusdóttir, Þórhildur; Guðmundsson, Kjartan R.; Sæmundsdóttir, Jóna; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Sigurðsson, Ásgeir; Manzanillo, Paolo; Guðjónsson, Sigurjón Axel; Thorisson, Gudmundur A.; Magnússon, Ólafur Þ.; Másson, Gísli; Örvar, Kjartan B.; Holm, Hilma; Björnsson, Sigurður; Arngrimsson, Reynir; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Haraldsson, Ásgeir; sulem, patrick; Stefansson, Kari (Springer Science and Business Media LLC, 2018-10-25)
    Mutations in genes encoding subunits of the phagocyte NADPH oxidase complex are recognized to cause chronic granulomatous disease (CGD), a severe primary immunodeficiency. Here we describe how deficiency of CYBC1, a previously uncharacterized protein ...
  • Icon
    Sequence variant at 4q25 near PITX2 associates with appendicitis 
    Kristjansson, Ragnar; Benonisdottir, Stefania; Oddsson, Asmundur; Galesloot, Tessel E.; Þorleifsson, Guðmar; Aben, Katja K.; Davíðsson, Ólafur B.; Jónsson, Stefán; Arnadottir, Gudny; Jensson, Brynjar Örn; Walters, G. Bragi; Sigurðsson, Jón K.; Sigurðsson, Snævar; Holm, Hilma; Arnar, Davíð O.; Thorgeirsson, Gudmundur; Alexíusdóttir, Kristín; Jonsdottir, Ingileif; Thorsteinsdottir, Unnur; Kiemeney, Lambertus A.; Jónsson, Þorvaldur; Gudbjartsson, Daniel; Rafnar, Thorunn; sulem, patrick; Stefansson, Kari (Springer Nature, 2017-06-08)
    Appendicitis is one of the most common conditions requiring acute surgery and can pose a threat to the lives of affected individuals. We performed a genome-wide association study of appendicitis in 7,276 Icelandic and 1,139 Dutch cases and large groups ...
  • Icon
    Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse model 
    Jóelsson, Jón Pétur; Ásbjarnarson, Árni; Sigurðsson, Snævar; Kricker, Jennifer; Valdimarsdottir, Bryndis; Thorarinsdottir, Holmfridur; Starradottir, Eir; Guðjónsson, Þórarinn; Ingþórsson, Sævar; Kárason, Sigurbergur (2022-07-22)
    BACKGROUND: Mechanical ventilation is a life-saving therapy for critically ill patients, providing rest to the respiratory muscles and facilitating gas exchange in the lungs. Ventilator-induced lung injury (VILI) is an unfortunate side effect of ...