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Browsing by Author "Stirnimann, Guido"

Browsing by Author "Stirnimann, Guido"

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    A new framework for advancing in drug-induced liver injury research. The Prospective European DILI Registry 
    Björnsson, Einar Stefán; Stephens, Camilla; Atallah, Edmond; Robles-Diaz, Mercedes; Alvarez-Alvarez, Ismael; Gerbes, Alexander; Weber, Sabine; Stirnimann, Guido; Kullak-Ublick, Gerd; Cortez-Pinto, Helena; Grove, Jane I.; Lucena, M. Isabel; Andrade, Raul J.; Aithal, Guruprasad P. (2023-01-01)
    Background & Aims: No multi-national prospective study of drug-induced liver injury (DILI) has originated in Europe. The design of a prospective European DILI registry, clinical features and short-term outcomes of the cases and controls is reported. ...
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    Role of Corticosteroids in Drug-Induced Liver Injury. A Systematic Review 
    Björnsson, Einar Stefán; Vucic, Vesna; Stirnimann, Guido; Robles-Díaz, Mercedes (2022-02-10)
    Introduction: Apart from cessation of the implicated agent leading to drug-induced liver injury (DILI), there is no standard therapy for DILI. Corticosteroids have been used in DILI, although their efficacy is unclear. Published data showed either ...
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    Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans 
    Ravindra, Kodihalli C; Vaidya, Vishal S; Wang, Zhenyu; Federspiel, Joel D; Virgen-Slane, Richard; Everley, Robert A; Grove, Jane I; Stephens, Camilla; Ocana, Mireia F; Robles-Díaz, Mercedes; Isabel Lucena, M; Andrade, Raul J; Atallah, Edmond; Gerbes, Alexander L; Weber, Sabine; Cortez-Pinto, Helena; Fowell, Andrew J; Hussaini, Hyder; Björnsson, Einar Stefán; Patel, Janisha; Stirnimann, Guido; Verma, Sumita; Elsharkawy, Ahmed M; Griffiths, William J H; Hyde, Craig; Dear, James W; Aithal, Guruprasad P; Ramaiah, Shashi K (2023-03-03)
    Diagnosis of drug-induced liver injury (DILI) and its distinction from other liver diseases are significant challenges in drug development and clinical practice. Here, we identify, confirm, and replicate the biomarker performance characteristics of ...