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Browsing by Author "Helgason, Agnar Sturla"

Browsing by Author "Helgason, Agnar Sturla"

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    The genetic structure of Norway 
    Mattingsdal, Morten; Ebenesersdóttir, Sigríður Sunna; Moore, Kristjan Helgi Swerford; Andreassen, Ole A.; Hansen, Thomas Folkmann; Werge, Thomas M.; Kockum, Ingrid; Olsson, Tomas; Alfredsson, Lars; Helgason, Agnar Sturla; Stefánsson, Kári; Hovig, Eivind (2021-11)
    The aim of the present study was to describe the genetic structure of the Norwegian population using genotypes from 6369 unrelated individuals with detailed information about places of residence. Using standard single marker- and haplotype-based ...
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    Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis 
    Stacey, Simon N.; Zink, Florian; Halldórsson, Gísli Hreinn; Stefánsdóttir, Lilja; Guðjónsson, Sigurjón Axel; Einarsson, Gudmundur; Hjörleifsson, Grimur; Eiríksdóttir, Þjóðbjörg; Helgadottir, Anna; Björnsdottir, Gyda; Thorgeirsson, Thorgeir E.; Ólafsdóttir, Þórunn Ásta; Jónsdóttir, Ingileif; Gretarsdottir, Solveig; Tragante, Vinicius; Magnússon, Magnús Karl; Jonsson, Hakon; Gudmundsson, Julius; Olafsson, Sigurgeir; Holm, Hilma; Gudbjartsson, Daniel F.; Sulem, Patrick; Helgason, Agnar Sturla; Þorsteinsdóttir, Unnur; Tryggvadottir, Laufey; Rafnar, Thorunn; Melsted, Páll; Úlfarsson, Magnús Örn; Viðarsson, Brynjar; Thorleifsson, Gudmar; Stefánsson, Kári (2023-11-06)
    Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cells is derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of 45,510 Icelandic and 130,709 UK Biobank participants combined with a mutational ...
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    A population-based survey of FBN1 variants in Iceland reveals underdiagnosis of Marfan syndrome 
    Klemenzdottir, Elin Ola; Arnadottir, Gudny A; Jensson, Brynjar Orn; Jonasdottir, Adalbjorg; Katrinardottir, Hildigunnur; Fridriksdottir, Run; Jonasdottir, Aslaug; Sigurdsson, Asgeir; Gudjonsson, Sigurjon Axel; Jónsson, Jón Jóhannes; Stefánsdóttir, Vigdís Fjóla; Danielsen, Ragnar; Palsdottir, Astridur; Jonsson, Hakon; Helgason, Agnar Sturla; Magnusson, Olafur Thor; Thorsteinsdottir, Unnur; Björnsson, Hans Tómas; Stefansson, Kari; Sulem, Patrick (2023)
    Marfan syndrome (MFS) is an autosomal dominant condition characterized by aortic aneurysm, skeletal abnormalities, and lens dislocation, and is caused by variants in the FBN1 gene. To explore causes of MFS and the prevalence of the disease in Iceland ...