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Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines : randomized controlled clinical trials conducted by the BIOVACSAFE consortium

Weiner, January; Lewis, David J.M.; Maertzdorf, Jeroen; Mollenkopf, Hans Joachim; Bodinham, Caroline; Pizzoferro, Kat; Linley, Catherine; Greenwood, Aldona; Mantovani, Alberto; Bottazzi, Barbara; Denoel, Philippe; Leroux-Roels, Geert; Kester, Kent E.; Jonsdottir, Ingileif; van den Berg, Robert; Kaufmann, Stefan H.E.; Del Giudice, Giuseppe (2019-12-01)

Biomarkers predictive of inflammatory events post-vaccination could accelerate vaccine development. Within the BIOVACSAFE framework, we conducted three identically designed, placebo-controlled inpatient/outpatient clinical studies (NCT01765413/NCT017 ...

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