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Fletta eftir höfundi "Ingvarsson, Sigurður"

Fletta eftir höfundi "Ingvarsson, Sigurður"

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    The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity 
    Foxler, Daniel E.; Bridge, Katherine S.; James, Victoria; Webb, Thomas M.; Mee, Maureen; Wong, Sybil C. K.; Feng, Yunfeng; Constantin-Teodosiu, Dumitru; Petursdottir, Thorgunnur Eyfjord; Bjornsson, Johannes; Ingvarsson, Sigurður; Ratcliffe, Peter J.; Longmore, Gregory D.; Sharp, Tyson V. (Springer Nature, 2012-01-29)
    There are three prolyl hydroxylases (PHD1, 2 and 3) that regulate the hypoxia-inducible factors (HIFs), the master transcriptional regulators that respond to changes in intracellular O(2) tension. In high O(2) tension (normoxia) the PHDs hydroxylate ...
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    MicroRNA-451 suppresses tumor cell growth by down-regulating IL6R gene expression 
    Liu, Dong; Liu, Cong; Wang, Xiyin; Ingvarsson, Sigurður; Chen, Huiping (Elsevier Ltd., 2014-02)
    The miR-451 was found to be frequently down-regulated in tumors, indicating that miR-451 could play an important role in carcinogenesis. This study uncovered the mechanism by which the miR-451 functions as a tumor suppressor. The target genes of miR-451 ...
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    Myc family of genes; structure, expression, and activation in tumor pathogenesis. 
    Ingvarsson, Sigurður (Karolinska Institutet, Department of Tumor Biology, 1989-10-27)
    The aim of this study has been tq identify the structural changes during c-myc activation · in relation to tumor pathogenesis, to characterize the Bmyc gene, and to compare the structure and expression of myc gene family members. The myc family members ...
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    Universal RNA editing in a human liver at the fetal stage 
    Liu, Dong; Liu, Cong; Wang, Xiyin; Ingvarsson, Sigurður; Chen, Huiping (Scientific Research Publishing, Inc,, 2012)
    It is known that RNA editing occurs in human cells, which can change the information transmission from DNA to RNA and proteins. Most previous studies have focused on editing of the mRNAs. Here we reported that several kinds of RNAs, including miRNA, ...
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    Vísindadagur Keldna 2023 
    Ingvarsson, Sigurður; Sigurðardóttir, Anna Karen; Erlingsdóttir, Ásthildur; Bragason, Birkir Thor (Tilraunastöð Háskóla Íslands í meinafræði að Keldum, 2023-04-19)
    Tilraunastöð Háskóla Íslands í meinafræði að Keldum fagnar sjötíu og fimm ára starfsafmæli í ár. Af því tilefni er ráðstefna/vísindadagur sem fer fram 19. apríl 2023 á bókasafni Tilraunastöðvarinnar. Tilraunastöðin starfar fyrst og fremst sem rannsóknastofa ...