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Browsing by Author "Lund, S.H."

Browsing by Author "Lund, S.H."

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    Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset 
    Sævarsdóttir, Sædís; Stefansdottir, Lilja; Sulem, P.; Thorleifsson, G.; Ferkingstad, E.; Rutsdottir, G.; Glintborg, B.; Westerlind, H.; Gröndal, Gerður María; Loft, I.C.; Sorensen, S.B.; Lie, B.A.; Brink, M.; Arlestig, L.; Arnthorsson, A.O.; Baecklund, E.; Banasik, K.; Bank, S.; Bjorkman, L.I.; Ellingsen, T.; Erikstrup, C.; Frei, O.; Gjertsson, I.; Gudbjartsson, D.F.; Gudjonsson, S.A.; Halldorsson, G.H.; Hendricks, O.; Hillert, J.; Hogdall, E.; Jacobsen, Sø; Jensen, D.V.; Jonsson, Helgi; Kastbom, A.; Kockum, I.; Kristensen, S.; Kristjansdottir, Helga; Larsen, M.H.; Linauskas, A.; Hauge, E.-M.; Loft, A.G.; Lúðvíksson, Björn Rúnar; Lund, S.H.; Markusson, Þorsteinn; Masson, G.; Melsted, P.; Moore, K.H.S.; Munk, H.; Nielsen, K.R.; Norddahl, G.L.; Oddsson, A.; Olafsdottir, T.A.; Olason, P.I.; Olsson, T.; Ostrowski, S.R.; Hørslev-Petersen, K.; Rognvaldsson, S.; Sanner, H.; Silberberg, G.N.; Stefansson, H.; Sørensen, E.; Sørensen, I.J.; Turesson, C.; Bergman, T.; Alfredsson, L.; Kvien, T.K.; Brunak, Sø; Steinsson, K.; Andersen, V.; Andreassen, O.A.; Rantapää-Dahlqvist, S.; Hetland, M.L.; Klareskog, L.; Askling, J.; Padyukov, L.; Pedersen, O.B.V.; Thorsteinsdottir, U.; Jonsdottir, I.; Stefánsson, Kári (2022-04-25)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...
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    Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects 
    Teitsdottir, U.D.; Darreh-Shori, T.; Lund, S.H.; Jonsdottir, M.K.; Snaedal, J.; Petersen, P.H. (2022-05-26)
    Background: Cholinergic drugs are the most commonly used drugs for the treatment of Alzheimer's disease (AD). Therefore, a better understanding of the cholinergic system and its relation to both AD-related biomarkers and cognitive functions is of high ...
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    The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in Iceland : A Large-Scale Proteomics Scan in Iceland 
    Styrkarsdottir, Unnur; Lund, S.H.; Saevarsdottir, S.; Magnusson, M.I.; Gunnarsdottir, K.; Norddahl, Gudmundur L.; Frigge, Michael L.; Ivarsdottir, E.V.; Bjornsdottir, Gyda; Holm, Hilma; Thorgeirsson, Guðmundur; Rafnar, T.; Jonsdottir, I.; Ingvarsson, T.; Jonsson, H.; Sulem, P.; Thorsteinsdottir, U.; Gudbjartsson, Daniel Fannar; Stefansson, K.; Thorgeirsson, Gudmundur; Ingvarsson, Þorvaldur (2021-11)
    Objective: Biomarkers for diagnosis and progression of osteoarthritis (OA) are lacking. This study was undertaken to identify circulating biomarkers for OA that could predict disease occurrence and/or progression to joint replacement. Methods: Using ...