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Fletta eftir höfundi "Seip, Kotryna"

Fletta eftir höfundi "Seip, Kotryna"

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    Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen 
    Barkovskaya, Anna; Goodwin, Craig M.; Seip, Kotryna; Hilmarsdottir, Bylgja; Pettersen, Solveig; Stalnecker, Clint; Engebraaten, Olav; Briem, Eiríkur; Der, Channing J.; Moestue, Siver A.; Gudjonsson, Thorarinn; Mælandsmo, Gunhild M.; Prasmickaite, Lina (2021-05-01)
    Cellular phenotype plasticity between the epithelial and mesenchymal states has been linked to metastasis and heterogeneous responses to cancer therapy, and remains a challenge for the treatment of triple-negative breast cancer (TNBC). Here, we used ...
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    O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes 
    Barkovskaya, Anna; Seip, Kotryna; Hilmarsdóttir, Bylgja; Maelandsmo, Gunhild M; Moestue, Siver A; Itkonen, Harri M (2019-04-05)
    Post-translational modification of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the enzyme that catalyzes ...