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Browsing by Author "Grétarsdóttir, Sólveig"

Browsing by Author "Grétarsdóttir, Sólveig"

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  • Björnsson, Eyþór; Þorleifsson, Guðmar; Helgadóttir, Anna; Gudnason, Thorarinn; Gudbjartsson, Tomas; Andersen, Karl; Grétarsdóttir, Sólveig; Ólafsson, Ísleifur; Tragante, Vinicius; Ólafsson, Ólafur Hreiðar; Jónsdóttir, Birna; Eyjólfsson, Guðmundur I.; Sigurðardóttir, Ólöf; Thorgeirsson, Gudmundur; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Holm, Hilma; Stefansson, Kari (American Medical Association (AMA), 2020-01-01)
    Importance: Genetic studies have evaluated the influence of blood lipid levels on the risk of coronary artery disease (CAD), but less is known about how they are associated with the extent of coronary atherosclerosis. Objective: To estimate the ...
  • Helgadottir, Anna; Thorleifsson, Gudmar; Grétarsdóttir, Sólveig; Stefánsson, Ólafur A.; Tragante, Vinicius; Þórólfsdóttir, Rósa B.; Jonsdottir, Ingileif; Björnsson, Þorsteinn; Steinthorsdottir, Valgerdur; Verweij, Niek; Nielsen, Jonas B.; Zhou, Wei; Folkersen, Lasse; Martinsson, Andreas; Heydarpour, Mahyar; Prakash, Siddharth; Óskarsson, Gylfi; Gudbjartsson, Tomas; Geirsson, Arnar; Olafsson, Isleifur; Sigurðsson, Emil Lárus; Almgren, Peter; Melander, Olle; Franco-Cereceda, Anders; Hamsten, Anders; Fritsche, Lars; Lin, Maoxuan; Yang, Bo; Hornsby, Whitney; Guo, Dongchuan; Brummett, Chad M.; Abecasis, Gonçalo; Mathis, Michael; Milewicz, Dianna; Body, Simon C.; Eriksson, Per; Willer, Cristen J.; Hveem, Kristian; Newton-Cheh, Christopher; Smith, J. Gustav; Danielsen, Ragnar; Thorgeirsson, Gudmundur; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Holm, Hilma; Stefansson, Kari (Springer Nature, 2018-03-07)
    Aortic valve stenosis (AS) is the most common valvular heart disease, and valve replacement is the only definitive treatment. Here we report a large genome-wide association (GWA) study of 2,457 Icelandic AS cases and 349,342 controls with a follow-up ...
  • Smith, Albert Vernon; Gudnason, Vilmundur; Grétarsdóttir, Sólveig; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Stefansson, Kari (Springer Science and Business Media LLC, 2018-12)
    Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses of genome-wide association studies (GWAS) in ...
  • Gudbjartsson, Daniel; Thorgeirsson, Gudmundur; Sulem, Patrick; Helgadottir, Anna; Gylfason, Arnaldur; Sæmundsdóttir, Jóna; Björnsson, Eyþór; Norðdahl, Guðmundur L.; Jónasdóttir, Áslaug; Jónasdóttir, Aðalbjörg; Eggertsson, Hannes; Grétarsdóttir, Sólveig; Thorleifsson, Gudmar; Indridason, Olafur Skuli; Palsson, Runolfur; Jónasson, Friðbert; Jonsdottir, Ingileif; Eyjólfsson, Guðmundur I.; Sigurðardóttir, Ólöf; Ólafsson, Ísleifur; Danielsen, Ragnar; Matthíasson, Stefán E.; Kristmundsdóttir, Snædís; Halldórsson, Bjarni V.; Hreiðarsson, Ástráður Benedikt; Valdimarsson, Einar M.; Gudnason, Thorarinn; Benediktsson, Rafn; Steinthorsdottir, Valgerdur; Thorsteinsdottir, Unnur; Holm, Hilma; Stefansson, Kari (Elsevier BV, 2019-12-17)
    Background: Lipoprotein(a) [Lp(a)] is a causal risk factor for cardiovascular diseases that has no established therapy. The attribute of Lp(a) that affects cardiovascular risk is not established. Low levels of Lp(a) have been associated with type 2 ...
  • Björnsson, Þorsteinn; Þórólfsdóttir, Rósa B.; Sveinbjornsson, Gardar; Sulem, Patrick; Norðdahl, Guðmundur L.; Helgadóttir, Anna; Grétarsdóttir, Sólveig; Magnusdóttir, Auður; Danielsen, Ragnar; Sigurðsson, Emil Lárus; Adalsteinsdottir, Berglind; Gunnarsson, Sverrir I; Jonsdottir, Ingileif; Arnar, Davíð O.; Helgason, Hróðmar; Gudbjartsson, Tomas; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Holm, Hilma; Stefansson, Kari (Oxford University Press (OUP), 2018-03-24)
    Aims Coarctation of the aorta (CoA) accounts for 4-8% of congenital heart defects (CHDs) and confers substantial morbidity despite treatment. It is increasingly recognized as a highly heritable condition. The aim of the study was to search for sequence ...
  • Helgadottir, Anna; Sulem, Patrick; Thorgeirsson, Gudmundur; Grétarsdóttir, Sólveig; Thorleifsson, Gudmar; Jensson, Brynjar Örn; Arnadottir, Gudny; Olafsson, Isleifur; Eyjólfsson, Guðmundur I.; Sigurdardottir, Olof; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Holm, Hilma; Stefansson, Kari (Oxford University Press (OUP), 2018-03-27)
    Aims Scavenger receptor Class B Type 1 (SR-BI) is a major receptor for high-density lipoprotein (HDL) that promotes hepatic uptake of cholesterol from HDL. A rare mutation p.P376L, in the gene encoding SR-BI, SCARB1, was recently reported to associate ...
  • Norland, Kristján; Sveinbjornsson, Gardar; Thorolfsdottir, Rosa B; Davidsson, Olafur B.; Tragante, Vinicius; Rajamani, Sridharan; Helgadottir, Anna; Grétarsdóttir, Sólveig; van Setten, Jessica; Asselbergs, Folkert W.; Sverrisson, Jon Th.; Stephensen, Sigurdur Sverrir; Óskarsson, Gylfi; Sigurðsson, Emil Lárus; Andersen, Karl; Danielsen, Ragnar; Thorgeirsson, Gudmundur; Thorsteinsdottir, Unnur; Arnar, Davíð O.; Sulem, Patrick; Holm, Hilma; Gudbjartsson, Daniel; Stefansson, Kari (Springer Science and Business Media LLC, 2019-10-22)
    Features of the QRS complex of the electrocardiogram, reflecting ventricular depolarisation, associate with various physiologic functions and several pathologic conditions. We test 32.5 million variants for association with ten measures of the QRS ...