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Fletta eftir höfundi "Holmstrøm, Kim"

Fletta eftir höfundi "Holmstrøm, Kim"

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    Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis 
    Aldi, Silvia; Matic, Ljubica Perisic; Hamm, Gregory; van Keulen, Daniëlle; Tempel, Dennie; Holmstrøm, Kim; Szwajda, Agnieszka; Nielsen, Boye Schnack; Emilsson, Valur; Ait-Belkacem, Rima; Lengquist, Mariette; Paulsson-Berne, Gabrielle; Eriksson, Per; Lindeman, Jan H.N.; Gool, Alain J.; Stauber, Jonathan; Hedin, Ulf; Hurt-Camejo, Eva (Elsevier BV, 2018-09-21)
    Variants in thePLPP3gene encoding for lipid phosphatephosphohydrolase 3 have been associated with susceptibilityto atherosclerosis independently of classical risk factors.PLPP3 inactivates lysophosphatidic acid (LPA), a pro-inflam-matory, pro-thrombotic ...
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    Oncostatin M reduces atherosclerosis development in APOE3Leiden.CETP mice and is associated with increased survival probability in humans 
    van Keulen, Danielle; Pouwer, Marianne G.; Emilsson, Valur; Matic, Ljubica Perisic; Pieterman, Elsbet J.; Hedin, Ulf; Gudnason, Vilmundur; Jennings, Lori L.; Holmstrøm, Kim; Nielsen, Boye Schnack; Pasterkamp, Gerard; Lindeman, Jan H.N.; van Gool, Alain J.; Sollewijn Gelpke, Maarten D.; Princen, Hans M.G.; Tempel, Dennie (2019-08-01)
    Objective Previous studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and ...