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Browsing by Author "Ostrowski, Sisse Rye"

Browsing by Author "Ostrowski, Sisse Rye"

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    Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)—a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy 
    Berthelsen, Rasmus Ehrenfried; Ostrowski, Sisse Rye; Bestle, Morten Heiberg; Johansson, Pär Ingemar (Springer Science and Business Media LLC, 2019-09-05)
    Background: Part of the pathophysiology in septic shock is a progressive activation of the endothelium and platelets leading to widespread microvascular injury with capillary leakage, microthrombi and consumption coagulopathy. Modulating the inflammatory ...
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    A partial loss-of-function variant in STAT6 protects against type 2 asthma 
    Kristjansdottir, Katla; Norddahl, Gudmundur L; Ivarsdottir, Erna V; Halldórsson, Gísli Hreinn; Einarsson, Gudmundur; Bjarnadottir, Kristbjorg; Rutsdottir, Gudrun; Arnthorsson, Asgeir O; Erikstrup, Christian; Gudmundsdottir, Steinunn; Gunnarsdottir, Kristbjorg; Gunnbjörnsdóttir, María I; Halldórsson, Bjarni Vilhjálmur; Holm, Hilma; Lúðvíksdóttir, Dóra; Lúðvíksson, Björn Rúnar; Brunak, Søren; Bruun, Mie Topholm; Mikkelsen, Christina; Mikkelsen, Susan; Jensen, Bitten Aagaard; Sørensen, Erik; Thomsen, Simon Francis; Ullum, Henrik; Ólafsson, Ísleifur; Önundarson, Páll Torfi; Ostrowski, Sisse Rye; Sævarsdóttir, Sædís; Sigurdardottir, Olof; Sigurgeirsson, Bardur; Snaebjarnarson, Audunn S; Sveinbjornsson, Gardar; Thorlacius, Gudny E; Thorleifsson, Gudmar; Tragante, Vinicius; Vidarsson, Brynjar; Porsbjerg, Celeste; Björnsdóttir, Unnur Steina; Sulem, Patrick; Gudbjartsson, Daniel F; Melsted, Páll; Pedersen, Ole Bv; Jónsdóttir, Ingileif; Olafsdottir, Thorunn A; Stefánsson, Kári (2024-10-16)
    BACKGROUND: Signal transducer and activator of transcription 6 (STAT6) is central to type 2 (T2) inflammation, and common noncoding variants at the STAT6 locus associate with various T2 inflammatory traits, including diseases, and its pathway is widely ...
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    Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism 
    Johansson, Pär Ingemar; Stensballe, Jakob; Ostrowski, SisseRye (Springer Nature, 2017-02-09)
    One quarter of patients suffering from acute critical illness such as severe trauma, sepsis, myocardial infarction (MI) or post cardiac arrest syndrome (PCAS) develop severe hemostatic aberrations and coagulopathy, which are associated with excess ...