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Fletta eftir efnisorði "DNA-rannsóknir"

Fletta eftir efnisorði "DNA-rannsóknir"

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    Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution 
    Louphrasitthiphol, Pakavarin; Siddaway, Robert; Loffreda, Alessia; Pogenberg, Vivian; Friedrichsen, Hans; Schepsky, Alexander; Zeng, Zhiqiang; Lu, Min; Strub, Thomas; Freter, Rasmus; Lisle, Richard; Suer, Eda; Thomas, Benjamin; Schuster-Böckler, Benjamin; Filippakopoulos, Panagis; Middleton, Mark; Lu, Xin; Patton, E. Elizabeth; Davidson, Irwin; Lambert, Jean-Philippe; Wilmanns, Matthias; Steingrimsson, Eirikur; Mazza, Davide; Goding, Colin R. (Elsevier BV, 2020-08-06)
    It is widely assumed that decreasing transcription factor DNA-binding affinity reduces transcription initiation by diminishing occupancy of sequence-specific regulatory elements. However, in vivo transcription factors find their binding sites while ...
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    Unraveling the mechanism of DNA methylation regulation during early embryo epigenetic reprogramming 
    Grétarsson, Kristján Hólm (University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-12)
    Umframerfðastjórnprótein taka þátt í að stjórna mismunandi genatjáningu og koma þannig up sérhæfðu umframerfðamengi í frumum sem allar hafa sama erfðamengið. Það er mikilvægt að skilja hvernig umframerfðamerkjum er stjórnað snemma í fósturþroskun ...
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    Whole genome characterization of sequence diversity of 15,220 Icelanders 
    Jónsson, Hákon; sulem, patrick; Kehr, Birte; Kristmundsdóttir, Snædís; Zink, Florian; Hjartarson, Eiríkur; Hardarson, Marteinn; Hjorleifsson, Kristjan; Eggertsson, Hannes; Guðjónsson, Sigurjón Axel; Ward, Lucas D.; Arnadottir, Gudny; Helgason, Einar A.; Helgason, Hannes; Gylfason, Arnaldur; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Rafnar, Thorunn; Besenbacher, Soren; Frigge, Michael L.; Stacey, Simon N.; Magnússon, Ólafur T.; Þorsteinsdóttir, Unnur; Másson, Gísli; Kong, Augustine; Halldórsson, Bjarni; Helgason, Agnar; Gudbjartsson, Daniel; Stefansson, Kari (Springer Nature, 2017-09-21)
    Understanding of sequence diversity is the cornerstone of analysis of genetic disorders, population genetics, and evolutionary biology. Here, we present an update of our sequencing set to 15,220 Icelanders who we sequenced to an average genome-wide ...