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Browsing by Subject "Cellular and Molecular Neuroscience"

Browsing by Subject "Cellular and Molecular Neuroscience"

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    Preferential activation of small cutaneous fibers through small pin electrode also depends on the shape of a long duration electrical current 
    Hugosdottir, Rosa; Mørch, Carsten Dahl; Andersen, Ole Kæseler; Helgason, Thordur; Arendt-Nielsen, Lars (Springer Science and Business Media LLC, 2019-09-14)
    Background Electrical stimulation is widely used in experimental pain research but it lacks selectivity towards small nociceptive fibers. When using standard surface patch electrodes and rectangular pulses, large fibers are activated at a lower threshold ...
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    Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Prevention Initiative (API) Generation Studies 
    Tariot, Pierre N.; Riviere, Marie Emmanuelle; Salloway, Stephen; Burns, Jeffrey M.; Snædal, Jón G; Borowsky, Beth; Lopez, Cristina Lopez; Liu, Fonda; Rouzade-Dominguez, Marie Laure; Cazorla, Pilar; Mousseau, Marie Catherine; Arkuszewski, Michal; Ricart, Javier; Viglietta, Vissia; Sui, Yihan; Caputo, Angelika; Langbaum, Jessica B.; Reiman, Eric M.; Graf, Ana (2024-11)
    INTRODUCTION: The Alzheimer's Prevention Initiative (API) Generation Studies evaluated the BACE inhibitor umibecestat for Alzheimer's disease (AD) prevention. The studies were terminated early, and the reversibility of umibecestat's side effects was ...
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    Sex differences in brain atrophy in dementia with Lewy bodies 
    Oltra, Javier; Habich, Annegret; Schwarz, Christopher G.; Nedelska, Zuzana; Przybelski, Scott A.; Inguanzo, Anna; Diaz-Galvan, Patricia; Lowe, Val J.; Oppedal, Ketil; Gonzalez, Maria C.; Philippi, Nathalie; Blanc, Frederic; Barkhof, Frederik; Lemstra, Afina W.; Hort, Jakub; Padovani, Alessandro; Rektorova, Irena; Bonanni, Laura; Massa, Federico; Kramberger, Milica G.; Taylor, John Paul; Snædal, Jón G; Walker, Zuzana; Antonini, Angelo; Dierks, Thomas; Segura, Barbara; Junque, Carme; Westman, Eric; Boeve, Bradley F.; Aarsland, Dag; Kantarci, Kejal; Ferreira, Daniel (2024-03)
    INTRODUCTION: Sex influences neurodegeneration, but it has been poorly investigated in dementia with Lewy bodies (DLB). We investigated sex differences in brain atrophy in DLB using magnetic resonance imaging (MRI). METHODS: We included 436 patients ...
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    Spatiotemporal phase slip patterns for visual evoked potentials, covert object naming tasks, and insight moments extracted from 256 channel EEG recordings 
    Ramon, Ceon; Graichen, Uwe; Gargiulo, Paolo; Zanow, Frank; Knösche, Thomas R.; Haueisen, Jens (2023-06-13)
    Phase slips arise from state transitions of the coordinated activity of cortical neurons which can be extracted from the EEG data. The phase slip rates (PSRs) were studied from the high-density (256 channel) EEG data, sampled at 16.384 kHz, of five ...
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    Trans-ethnic genomic informed risk assessment for Alzheimer's disease : An International Hundred K+ Cohorts Consortium study 
    Sleiman, Patrick M.; Qu, Hui Qi; Connolly, John J.; Mentch, Frank; Pereira, Alexandre; Lotufo, Paulo A.; Tollman, Stephen; Choudhury, Ananyo; Ramsay, Michele; Kato, Norihiro; Ozaki, Kouichi; Mitsumori, Risa; Jeon, Jae Pil; Hong, Chang Hyung; Son, Sang Joon; Roh, Hyun Woong; Lee, Dong gi; Mukadam, Naaheed; Foote, Isabelle F.; Marshall, Charles R.; Butterworth, Adam; Prins, Bram P.; Glessner, Joseph T.; Hakonarson, Hakon (2023-12)
    BACKGROUND: As a collaboration model between the International HundredK+ Cohorts Consortium (IHCC) and the Davos Alzheimer's Collaborative (DAC), our aim was to develop a trans-ethnic genomic informed risk assessment (GIRA) algorithm for Alzheimer's ...