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Browsing by Subject "Pharmacoepidemiology"

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Anticholinergic medicines use among older adults before and after initiating dementia medicines

Narayan, Sujita W.; Pearson, Sallie‐Anne; Litchfield, Melisa; Le Couteur, David G.; Buckley, Nicholas; McLachlan, Andrew J.; Zoega, Helga (Wiley, 2019-07-07)

Aims: We investigated anticholinergic medicines use among older adults initiating dementia medicines. Methods: We used Pharmaceutical Benefits Scheme dispensing claims to identify patients who initiated donepezil, rivastigmine, galantamine or memantine ...
Antidiabetic medication use during pregnancy: an international utilization study

Cesta, Carolyn E; Cohen, Jacqueline M; Pazzagli, Laura; Bateman, Brian T; Bröms, Gabriella; Einarsdottir, Kristjana; Furu, Kari; Havard, Alys; Heino, Anna; Hernandez-Diaz, Sonia; Huybrechts, Krista F; Karlstad, Øystein; Kieler, Helle; Li, Jiong; Leinonen, Maarit K; Gulseth, Hanne L; Tran, Duong; Yu, Yongfu; Zoega, Helga; Odsbu, Ingvild (BMJ, 2019-11-01)

Objective Diabetes in pregnancy and consequently the need for treatment with antidiabetic medication (ADM) has become increasingly prevalent. The prevalence and patterns of use of ADM in pregnancy from 2006 onward in seven different countries was ...
Incidence of direct oral anticoagulant use in patients with nonvalvular atrial fibrillation and characteristics of users in 6 European countries (2008–2015): A cross‐national drug utilization study

Ibáñez, Luisa; Sabaté, Mònica; Vidal, Xavier; Ballarin, Elena; Rottenkolber, Marietta; Schmiedl, Sven; Heeke, Andreas; Huerta, Consuelo; Martin Merino, Elisa; Montero, Dolores; Leon‐Muñoz, Luz María; Gasse, Christiane; Moore, Nicholas; Droz, Cécile; Lassalle, Régis; Aakjær, Mia; Andersen, Morten; De Bruin, Marie Louise; Groenwold, Rolf; Ham, Hendrika A.; Souverein, Patrick; Klungel, Olaf; Gardarsdottir, Helga (Wiley, 2019-09-04)

Aims: To estimate the incidence of direct oral anticoagulant drug (DOAC) use in patients with nonvalvular atrial fibrillation and to describe user and treatment characteristics in 8 European healthcare databases representing 6 European countries. ...
Passing the acid test? Evaluating the impact of national education initiatives to reduce proton pump inhibitor use in Australia

Bruno, Claudia; Pearson, Sallie-Anne; Daniels, Benjamin; Buckley, Nicholas A; Schaffer, Andrea; Zoega, Helga (BMJ, 2020-04-20)

Background Proton pump inhibitor (PPI) use is widespread. There have been increasing concerns about overuse of high-dose PPIs for durations longer than clinically necessary. Objective To evaluate the impact of national education initiatives on reducing ...
Prevalence trends and individual patterns of antiepileptic drug use in pregnancy 2006‐2016: A study in the five Nordic countries, United States, and Australia

Cohen, Jacqueline M.; Cesta, Carolyn E.; Furu, Kari; Einarsdóttir, Kristjana; Gissler, Mika; Havard, Alys; Hernandez‐Diaz, Sonia; Huybrechts, Krista F.; Kieler, Helle; Leinonen, Maarit K.; Li, Jiong; Reutfors, Johan; Schaffer, Andrea; Selmer, Randi; Yu, Yongfu; Zoega, Helga; Karlstad, Øystein (Wiley, 2020-06-03)

Purpose: To describe recent international trends in antiepileptic drug (AED) use during pregnancy and individual patterns of use including discontinuation and switching. Methods: We studied pregnancies from 2006 to 2016 within linked population-based ...
Proton pump inhibitor use among adults: Mapping the landscape of PPI use and exploring its effect on cancer risk and mortality

Hálfdánarson, Óskar (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-03-08)

Background and aims: Proton pump inhibitors (PPIs) are commonly prescribed drugs that are used to treat acid-related disorders of the gastrointestinal tract. Over the last decade, PPI use has repeatedly been shown to be increasing worldwide, causing ...
Quality of reporting of drug exposure in pharmacoepidemiological studies

Hempenius, Mirjam; Luijken, Kim; Boer, Anthonius; Klungel, Olaf; Groenwold, Rolf; Gardarsdottir, Helga (Wiley, 2020-05-11)

Purpose: Exposure definitions vary across pharmacoepidemiological studies. Therefore, transparent reporting of exposure definitions is important for interpretation of published study results. We aimed to assess the quality of reporting of exposure to ...

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