Browsing by Subject "DESI-MSI"

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Automated Cancer Diagnostics via Analysis of Optical and Chemical Images by Deep and Shallow Learning

Ísberg, Ólöf Gerður; Giunchiglia, Valentina; McKenzie, James S.; Takats, Zoltan; Jónasson, Jón Gunnlaugur; Bodvarsdottir, Sigridur Klara; Þorsteinsdóttir, Margrét; Xiang, Yuchen (2022-05-18)

Optical microscopy has long been the gold standard to analyse tissue samples for the diagnostics of various diseases, such as cancer. The current diagnostic workflow is time-consuming and labour-intensive, and manual annotation by a qualified pathologist ...
The effect of sample age on the metabolic information extracted from formalin-fixed and paraffin embedded tissue samples using desorption electrospray ionization mass spectrometry imaging

Ísberg, Ólöf Gerður; Xiang, Yuchen; Böðvarsdóttir, Sigríður Klara; Jónasson, Jón Gunnlaugur; Þorsteinsdóttir, Margrét; Takats, Zoltan (2021-11)

Background: Metabolites, especially lipids, have been shown to be promising therapeutic targets. In conjugation with genes and proteins they can be used to identify phenotypes of disease and support the development of targeted treatments. The majority ...

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