Browsing by Subject "Clozapine"

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Adverse drug reactions of antipsychotic drug treatment – how to balance evidence and values in relation to the use of clozapine in treatment-resistant schizophrenia

Ingimarsson, Oddur (University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-04-10)

Background: Schizophrenia is a chronic serious mental disorder with prevalence close to 0.7%. Early symptoms of schizophrenia generally appear in late adolescence or the early twenties. The prognosis is usually worse in cases of early onset. The ...
Neutropenia and agranulocytosis during treatment of schizophrenia with clozapine versus other antipsychotics: an observational study in Iceland

Ingimarsson, Oddur; MacCabe, James; Haraldsson, Magnús; Jónsdóttir, Halldóra; Sigurdsson, Engilbert (Springer Nature, 2016-12)

Background Data on the haematological outcomes of patients who continue clozapine treatment following neutropenia are very rare as even mild neutropenia results in mandatory discontinuation of clozapine in most countries. However, in Iceland where ...

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