Browsing by Subject "CTNNB1"

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Screening and computational analysis of colorectal associated non-synonymous polymorphism in CTNNB1 gene in Pakistani population

Razak, Suhail; Bibi, Nousheen; Dar, Javid Ahmad; Afsar, Tayyaba; Almajwal, Ali; Parveen, Zahida; Jahan, Sarwat (Springer Science and Business Media LLC, 2019-11-07)

Background: Colorectal cancer (CRC) is categorized by alteration of vital pathways such as β-catenin (CTNNB1) mutations, WNT signaling activation, tumor protein 53 (TP53) inactivation, BRAF, Adenomatous polyposis coli (APC) inactivation, KRAS, dysregulation ...

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