Opin vísindi
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Browsing by Subject "Blóðþynningarlyf"

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Comparison of the efficacy, safety, and adherence of oral anticoagulants

Ingason, Arnar Bragi (University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-05-27)

Oral anticoagulants (OACs) are among the most commonly used medication worldwide. Vitamin K antagonists, such as warfarin, were the only available oral anticoagulants for over 60 years. However, in the 2010s, novel direct oral anticoagulants (DOACs) ...
Replacement of traditional prothrombin time monitoring with the new Fiix prothrombin time increases the efficacy of warfarin without increasing bleeding. A review article

Önundarson, Páll Torfi; Palsson, Ragnar; Witt, Daniel M.; Gudmundsdottir, Brynja R. (2021-10-15)

The antithrombotic effect of vitamin K antagonists (VKA) depends on controlled lowering of the activity of factors (F) II and X whereas reductions in FVII and FIX play little role. PT-INR based monitoring, however, is highly influenced by FVII, which ...

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