Browsing by Subject "Alkylating agents"

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Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapy

Stukenborg, J -B; Alves-Lopes, J P; Kurek, M; Albalushi, H; Reda, A; Keros, V; Töhönen, V; Bjarnason, Ragnar Grímur; Romerius, P; Sundin, M; Norén Nyström, U; Langenskiöld, C; Vogt, H; Henningsohn, L; Mitchell, R T; Söder, O; Petersen, C; Jahnukainen, K (Oxford University Press (OUP), 2018-07-25)

STUDY QUESTION: Does chemotherapy exposure (with or without alkylating agents) or primary diagnosis affect spermatogonial quantity in human prepubertal testicular tissue? SUMMARY ANSWER: Spermatogonial quantity is significantly reduced in testes of ...

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