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Browsing by Journal title "Journal of the American Chemical Society"

Browsing by Journal title "Journal of the American Chemical Society"

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    Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding Process 
    Choudhary, Dhawal; Mediani, Laura; Avellaneda, Mario J.; Bjarnason, Sveinn; Alberti, Simon; Boczek, Edgar E.; Heidarsson, Pétur O.; Mossa, Alessandro; Carra, Serena; Tans, Sander J.; Cecconi, Ciro (American Chemical Society (ACS), 2023-07-06)
    Small Heat Shock Proteins (sHSPs) are key components of our Protein Quality Control system and are thought to act as reservoirs that neutralize irreversible protein aggregation. Yet, sHSPs can also act as sequestrases, promoting protein sequestration ...