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Browsing by Author "Karvelsson, Sigurður Trausti"

Browsing by Author "Karvelsson, Sigurður Trausti"

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    Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer 
    Karvelsson, Sigurður Trausti; Wang, Qiong; Hilmarsdóttir, Bylgja; Sigurðsson, Arnar; Moestue, Siver Andreas; Mælandsmo, Gunhild Mari; Halldórsson, Skarphédinn; Guðmundsson, Steinn; Rolfsson, Óttar (2021-09-17)
    Epithelial-to-mesenchymal transition (EMT) is fundamental to both normal tissue development and cancer progression. We hypothesized that EMT plasticity defines a range of metabolic phenotypes and that individual breast epithelial metabolic phenotypes ...
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    Metabolic systems analysis of breast epithelial cells following epithelial-to-mesenchymal transition 
    Karvelsson, Sigurður Trausti (University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-02-25)
    Breast cancer is a heterogenous disease in which the mechanism for signalling, gene expression, metabolism and growth in breast tissue is deranged. Breast cancer is responsible for the death of over 600,000 people worldwide on a yearly basis. By ...