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Fletta eftir höfundi "Lardner, Emma"

Fletta eftir höfundi "Lardner, Emma"

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    Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients 
    Gustavsson, Simon T.; Enz, Tim J.; Tribble, James R.; Nilsson, Mattias; Lindqvist, Anna; Lindén, Christina; Hagström, Anna; Rutigliani, Carola; Lardner, Emma; Stålhammar, Gustav; Williams, Pete A.; Jóhannesson, Gauti (2023-11-01)
    PURPOSE: To investigate whether nicotinamide (NAM) modulates retinal vasculature in glaucoma. METHODS: This was a prospective controlled clinical trial investigating animal and human histopathology. Participants included normotensive and ocular ...
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    Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction 
    Tribble, James R.; Otmani, Amin; Sun, Shanshan; Ellis, Sevannah A.; Cimaglia, Gloria; Vohra, Rupali; Jöe, Melissa; Lardner, Emma; Venkataraman, Abinaya P.; Domínguez-Vicent, Alberto; Kokkali, Eirini; Rho, Seungsoo; Jóhannesson, Gauti; Burgess, Robert W.; Fuerst, Peter G.; Brautaset, Rune; Kolko, Miriam; Morgan, James E.; Crowston, Jonathan G.; Votruba, Marcela; Williams, Pete A. (2021-07)
    Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. We assess the effects of nicotinamide (a precursor to ...