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Browsing by Author "Jakobsson, Per-Johan"

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Anti–Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis

Westerlind, Helga; Rönnelid, Johan; Hansson, Monika; Alfredsson, Lars; Mathsson‐Alm, Linda; Serre, Guy; Cornillet, Martin; Holmdahl, Rikard; Jakobsson, Per‐Johan; Skriner, Karl; Klareskog, Lars; Saevarsdottir, Saedis; Askling, Johan (Wiley, 2020-09-07)

Objective: To investigate the relationship between anti–citrullinated protein antibodies (ACPAs), specific ACPA subspecificities, rheumatoid factor (RF) isotypes, and incident cardiovascular (CV) events in patients with rheumatoid arthritis (RA). ...
Presence of autoantibodies in “seronegative” rheumatoid arthritis associates with classical risk factors and high disease activity

Reed, Evan; Hedström, Anna Karin; Hansson, Monika; Mathsson-Alm, Linda; Brynedal, Boel; Saevarsdottir, Saedis; Cornillet, Martin; Jakobsson, Per-Johan; Holmdahl, Rikard; Skriner, Karl; Serre, Guy; Alfredsson, Lars; Rönnelid, Johan; Lundberg, Karin (Springer Science and Business Media LLC, 2020-07-16)

Background: Rheumatoid arthritis (RA) is classified as seropositive or seronegative, depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti-citrullinated protein antibodies (ACPA), commonly detected using anti-cyclic ...
Urinary prostanoids are elevated by anti-TNF and anti-IL6 receptor disease-modifying antirheumatic drugs but are not predictive of response to treatment in early rheumatoid arthritis

Liu, Jianyang; Idborg, Helena; Korotkova, Marina; Lend, Kristina; van Vollenhoven, Ronald; Lampa, Jon; Rudin, Anna; Nordström, Dan; Guðbjörnsson, Björn; Gröndal, Gerður María; Uhlig, Till; Hørslev-Petersen, Kim; Lund Hetland, Merete; Østergaard, Mikkel; Nurmohamed, Michael; Jakobsson, Per-Johan (2024-03-05)

BACKGROUND: Disease-modifying antirheumatic drugs (DMARDs) are widely used for treating rheumatoid arthritis (RA). However, there are no established biomarkers to predict a patient's response to these therapies. Prostanoids, encompassing prostaglandins, ...

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