Opin vísindi

Fletta eftir höfundi "Halldorsson, Skarphedinn"

Fletta eftir höfundi "Halldorsson, Skarphedinn"

Röðun: Raða: Niðurstöður:

  • Icon
    Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia 
    Arason, Ari Jon; Jóelsson, Jón Pétur; Valdimarsdóttir, Bryndís; Sigurdsson, Snaevar; Guðjónsson, Alexander; Halldorsson, Skarphedinn; Jóhannsson, Freyr; Rolfsson, Óttar; Lehmann, Fredrik; Ingthorsson, Saevar; Cherek, Paulina; Gudmundsson, Gudmundur H; Garðarsson, Friðrik R.; Page, Clive P.; Baldursson, Ólafur; Gudjonsson, Thorarinn; Kricker, Jennifer (Springer Science and Business Media LLC, 2019-06-24)
    BACKGROUND: Azithromycin (Azm) is a macrolide recognized for its disease-modifying effects and reduction in exacerbation of chronic airway diseases. It is not clear whether the beneficial effects of Azm are due to its anti-microbial activity or other ...
  • Icon
    Glutamine-Fructose-6-Phosphate Transaminase 2 (GFPT2) Is Upregulated in Breast Epithelial-Mesenchymal Transition and Responds to Oxidative Stress 
    Wang, Qiong; Karvelsson, Sigurdur Trausti; Kotronoulas, Aristotelis; Gudjonsson, Thorarinn; Halldorsson, Skarphedinn; Rolfsson, Ottar (2022-02-01)
    Breast cancer cells that have undergone partial epithelial- mesenchymal transition (EMT) are believed to be more invasive than cells that have completed EMT. To study metabolic reprogramming in different mesenchymal states, we analyzed protein expression ...
  • Icon
    Metabolic re-wiring of isogenic breast epithelial cell lines following epithelial to mesenchymal transition 
    Halldorsson, Skarphedinn; Rohatgi, Neha; Magnúsdóttir, Manuela; Choudhary, Kumari Sonal; Gudjonsson, Thorarinn; Knutsen, Erik; Barkovskaya, Anna; Hilmarsdóttir, Bylgja; Perander, Maria; Mælandsmo, Gunhild M.; Guðmundsson, Steinn; Rolfsson, Óttar (Elsevier BV, 2017-06)
    Epithelial to mesenchymal transition (EMT) has implications in tumor progression and metastasis. Metabolic alterations have been described in cancer development but studies focused on the metabolic re-wiring that takes place during EMT are still limited. ...