Opin vísindi

Fletta eftir höfundi "Guðnason, Vilmundur G."

Fletta eftir höfundi "Guðnason, Vilmundur G."

Röðun: Raða: Niðurstöður:

  • Icon
    Algengi og nýgengi sykursýki 2 á Íslandi frá 2005 til 2018 
    Thórsson, Bolli; Guðmundsson, Elías Freyr; Sigurðsson, Gunnar; Aspelund, Thor; Guðnason, Vilmundur G. (2021-05)
    INNGANGUR Fjöldi fólks með sykursýki 2 hefur vaxið undanfarna áratugi á Íslandi. Í þessari rannsókn var notaður Lyfjagagnagrunnur Embættis landlæknis til að meta algengi og nýgengi sykursýki 2 og sett fram spá um algengi sykursýki 2 eftir 10 og 20 ár. ...
  • Icon
    Association of low-frequency and rare coding variants with information processing speed 
    Bressler, Jan; Davies, Gail; Smith, Albert Vernon; Saba, Yasaman; Bis, Joshua C.; Jian, Xueqiu; Hayward, Caroline; Yanek, Lisa; Smith, Jennifer A.; Mirza, Saira S.; Wang, Ruiqi; Adams, Hieab H.H.; Becker, Diane; Boerwinkle, Eric; Campbell, Archie; Cox, Simon R.; Eiríksdóttir, Guðný; Fawns-Ritchie, Chloe; Gottesman, Rebecca F.; Grove, Megan L.; Guo, Xiuqing; Hofer, Edith; Kardia, Sharon L.R.; Knol, Maria J.; Koini, Marisa; Lopez, Oscar L.; Marioni, Riccardo E.; Nyquist, Paul; Pattie, Alison; Polasek, Ozren; Porteous, David J.; Rudan, Igor; Satizabal, Claudia L.; Schmidt, Helena; Schmidt, Reinhold; Sidney, Stephen; Simino, Jeannette; Smith, Blair H.; Turner, Stephen T.; van der Lee, Sven J.; Ware, Erin B.; Whitmer, Rachel A.; Yaffe, Kristine; Yang, Qiong; Zhao, Wei; Guðnason, Vilmundur G.; Launer, Lenore J.; Fitzpatrick, Annette L.; Psaty, Bruce M.; Fornage, Myriam; Arfan Ikram, M.; van Duijn, Cornelia M.; Seshadri, Sudha; Mosley, Thomas H.; Deary, Ian J. (2021-12-04)
    Measures of information processing speed vary between individuals and decline with age. Studies of aging twins suggest heritability may be as high as 67%. The Illumina HumanExome Bead Chip genotyping array was used to examine the association of rare ...
  • Icon
    Cognition and brain health among older adults in Iceland : the AGES-Reykjavik study 
    Valsdóttir, Vaka; Magnúsdóttir, Brynja Björk; Chang, Milan; Sigurdsson, Sigurdur; Guðnason, Vilmundur G; Launer, Lenore J.; Jónsdóttir, María Kristín (2022-12)
    The paper aimed to compare how factors previously identified as predictive factors for cognitive decline and dementia related to cognitive performance on the one hand and brain health on the other. To that aim, multiple linear regression was applied ...
  • Icon
    Comparison of summer and winter objectively measured physical activity and sedentary behavior in older adults: Age, gene/environment susceptibility Reykjavik study 
    Arnardóttir, Nanna Ýr; Oskarsdottir, Nina Dora; Brychta, Robert J.; Koster, Annemarie; Van Domelen, Dane R.; Caserotti, Paolo; Eiriksdottir, Gudny; Sverrisdottir, Johanna E.; Johannsson, Erlingur; Launer, Lenore J.; Guðnason, Vilmundur G; Harris, Tamara B.; Chen, Kong Y.; Sveinsson, Þórarinn (2017-10-21)
    In Iceland, there is a large variation in daylight between summer and winter. The aim of the study was to identify how this large variation influences physical activity (PA) and sedentary behavior (SB). Free living PA was measured by a waist-worn ...
  • Icon
    Genome-wide association study of circulating interleukin 6 levels identifies novel loci 
    Ahluwalia, Tarunveer S.; Prins, Bram P.; Abdollahi, Mohammadreza; Armstrong, Nicola J.; Aslibekyan, Stella; Bain, Lisa; Jefferis, Barbara; Baumert, Jens; Beekman, Marian; Ben-Shlomo, Yoav; Bis, Joshua C.; Mitchell, Braxton D.; De Geus, Eco; Delgado, Graciela E.; Marek, Diana; Eriksson, Joel; Kajantie, Eero; Kanoni, Stavroula; Kemp, John P.; Lu, Chen; Marioni, Riccardo E.; McLachlan, Stela; Milaneschi, Yuri; Nolte, Ilja M.; Petrelis, Alexandros M.; Porcu, Eleonora; Sabater-Lleal, Maria; Naderi, Elnaz; Seppälä, Ilkka; Shah, Tina; Singhal, Gaurav; Standl, Marie; Teumer, Alexander; Thalamuthu, Anbupalam; Thiering, Elisabeth; Trompet, Stella; Ballantyne, Christie M.; Benjamin, Emelia J.; Casas, Juan P.; Toben, Catherine; Dedoussis, George; Deelen, Joris; Durda, Peter; Engmann, Jorgen; Feitosa, Mary F.; Grallert, Harald; Hammarstedt, Ann; Harris, Sarah E.; Homuth, Georg; Guðnason, Vilmundur G. (2021-01-30)
    Interleukin 6 (IL-6) is a multifunctional cytokine with both pro-A nd anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex disease ...
  • Icon
    Incidence of Brain Infarcts, Cognitive Change, and Risk of Dementia in the General Population : The AGES-Reykjavik Study (Age Gene/Environment Susceptibility-Reykjavik Study) 
    Sigurdsson, Sigurdur; Aspelund, Thor; Kjartansson, Ólafur; Gudmundsson, Elias Freyr; Jónsdóttir, María Kristín; Eiríksdóttir, Guðný; Jónsson, Pálmi V; van Buchem, Mark A.; Guðnason, Vilmundur G; Launer, Lenore J. (2017-09)
    BACKGROUND AND PURPOSE: The differentiation of brain infarcts by region is important because their cause and clinical implications may differ. Information on the incidence of these lesions and association with cognition and dementia from longitudinal ...
  • Icon
    A joint ventricle and WMH segmentation from MRI for evaluation of healthy and pathological changes in the aging brain 
    Atlason, Hans Emil; Löve, Áskell; Robertsson, Vidar; Blitz, Ari M.; Sigurdsson, Sigurdur; Guðnason, Vilmundur G; Ellingsen, Lotta María (2022-09-06)
    Age-related changes in brain structure include atrophy of the brain parenchyma and white matter changes of presumed vascular origin. Enlargement of the ventricles may occur due to atrophy or impaired cerebrospinal fluid (CSF) circulation. The co-occurrence ...
  • Icon
    Publisher Correction : A meta-analysis of genome-wide association studies identifies multiple longevity genes (Nature Communications, (2019), 10, 1, (3669), 10.1038/s41467-019-11558-2) 
    Deelen, Joris; Evans, Daniel S.; Arking, Dan E.; Tesi, Niccolò; Nygaard, Marianne; Liu, Xiaomin; Wojczynski, Mary K.; Biggs, Mary L.; van der Spek, Ashley; Atzmon, Gil; Ware, Erin B.; Sarnowski, Chloé; Smith, Albert V.; Seppälä, Ilkka; Cordell, Heather J.; Dose, Janina; Amin, Najaf; Arnold, Alice M.; Ayers, Kristin L.; Barzilai, Nir; Becker, Elizabeth J.; Beekman, Marian; Blanché, Hélène; Christensen, Kaare; Christiansen, Lene; Collerton, Joanna C.; Cubaynes, Sarah; Cummings, Steven R.; Davies, Karen; Debrabant, Birgit; Deleuze, Jean François; Duncan, Rachel; Faul, Jessica D.; Franceschi, Claudio; Galan, Pilar; Guðnason, Vilmundur G.; Harris, Tamara B.; Huisman, Martijn; Hurme, Mikko A.; Jagger, Carol; Jansen, Iris; Jylhä, Marja; Kähönen, Mika; Karasik, David; Kardia, Sharon L.R.; Kingston, Andrew; Kirkwood, Thomas B.L.; Launer, Lenore J.; Lehtimäki, Terho; Lieb, Wolfgang; Lyytikäinen, Leo Pekka; Martin-Ruiz, Carmen; Min, Junxia; Nebel, Almut; Newman, Anne B.; Nie, Chao; Nohr, Ellen A.; Orwoll, Eric S.; Perls, Thomas T.; Province, Michael A.; Psaty, Bruce M.; Raitakari, Olli T.; Reinders, Marcel J.T.; Robine, Jean Marie; Rotter, Jerome I.; Sebastiani, Paola; Smith, Jennifer; Sørensen, Thorkild I.A.; Taylor, Kent D.; Uitterlinden, André G.; van der Flier, Wiesje; van der Lee, Sven J.; van Duijn, Cornelia M.; van Heemst, Diana; Vaupel, James W.; Weir, David; Ye, Kenny; Zeng, Yi; Zheng, Wanlin; Holstege, Henne; Kiel, Douglas P.; Lunetta, Kathryn L.; Slagboom, P. Eline; Murabito, Joanne M. (2021-04-23)
    The original version of this Article contained an error in Fig. 1c, in which the top SNP was incorrectly labelled ‘rs4293358’. The correct label is ‘rs429358’. This has been corrected in both the PDF and HTML versions of the Article.
  • Icon
    Serum levels of ACE2 are higher in patients with obesity and diabetes 
    Emilsson, Valur; Guðmundsson, Elías F.; Aspelund, Thor; Jónsson, Brynjólfur G.; Guðjónsson, Alexander; Launer, Lenore J.; Lamb, John R.; Guðmundsdóttir, Valborg; Jennings, Lori L.; Guðnason, Vilmundur G. (2020-12-16)
    Objective: As severity of outcome in COVID-19 is disproportionately higher among individuals with obesity, smokers, patients with hypertension, kidney disease, chronic pulmonary disease, coronary heart disease (CHD), and/or type 2 diabetes (T2D), serum ...
  • Icon
    Soft tissue radiodensity parameters mediate the relationship between self-reported physical activity and lower extremity function in AGES-Reykjavík participants 
    Edmunds, Kyle J.; Okonkwo, Ozioma C.; Sigurðsson, Sigurður; Lose, Sarah R.; Guðnason, Vilmundur G.; Carraro, Ugo; Gargiulo, Paolo (2021-10-11)
    Although previous studies have highlighted the association between physical activity and lower extremity function (LEF) in elderly individuals, the mechanisms underlying this relationship remain debated. Our recent work has recognized the utility of ...