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Fletta eftir höfundi "Ásbjarnarson, Árni"

Fletta eftir höfundi "Ásbjarnarson, Árni"

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    Melflufen, a peptide‐conjugated alkylator, is an efficient anti‐neo‐plastic drug in breast cancer cell lines 
    Schepsky, Alexander; Traustadóttir, Gunnhildur Ásta; Jóelsson, Jón Pétur; Ingþórsson, Sævar; Kricker, Jennifer; Bergthorsson, Jon Thor; Ásbjarnarson, Árni; Gudjonsson, Thorkell; Nupponen, Nina; Slipicevic, Ana; Lehmann, Fredrik; Gudjonsson, Thorarinn (Wiley, 2020-07-27)
    Melphalan flufenamide (hereinafter referred to as “melflufen”) is a peptide-conjugated drug currently in phase 3 trials for the treatment of relapsed or refractory multiple myeloma. Due to its lipophilic nature, it readily enters cells, where it is ...
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    Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse model 
    Jóelsson, Jón Pétur; Ásbjarnarson, Árni; Sigurðsson, Snævar; Kricker, Jennifer; Valdimarsdottir, Bryndis; Thorarinsdottir, Holmfridur; Starradottir, Eir; Guðjónsson, Þórarinn; Ingþórsson, Sævar; Kárason, Sigurbergur (2022-07-22)
    BACKGROUND: Mechanical ventilation is a life-saving therapy for critically ill patients, providing rest to the respiratory muscles and facilitating gas exchange in the lungs. Ventilator-induced lung injury (VILI) is an unfortunate side effect of ...