Browsing by Author "Hayes, Polly"

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Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny

Magnadottir, Bergljot; Hayes, Polly; Gísladóttir, Berglind; Bragason, Birkir; Hristova, Mariya; Nicholas, Anthony P.; Guðmundsdóttir, Sigríður; Lange, Sigrun (Elsevier BV, 2018-10)

Pentraxins arefluid phase pattern recognition molecules that form an important part of the innate immunedefence and are conserved betweenfish and human. In Atlantic cod (Gadus morhuaL.), two pentraxin-likeproteins have been described, CRP-I and CRP-II. ...
Post-translational protein deimination in cod (Gadus morhua L.) ontogeny novel roles in tissue remodelling and mucosal immune defences?

Magnadottir, Bergljot; Hayes, Polly; Hristova, Mariya; Bragason, Birkir; Nicholas, Anthony P.; Dodds, Alister W.; Guðmundsdóttir, Sigríður; Lange, Sigrun (Elsevier BV, 2018-10)

Peptidylarginine deiminases (PADs) are calcium dependent enzymes with physiological and pathophysiologicalroles conserved throughout phylogeny. PADs promote post-translational deimination of protein arginine to ci-trulline, altering the structure and ...

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