Sturluson, Olafur OrriPálsson, ÓlafurHjaltested, Einar KristinnLúðvíksdóttir, Dóra2025-11-202025-11-202024-01-01Sturluson, O O, Pálsson, Ó, Hjaltested, E K & Lúðvíksdóttir, D 2024, 'Smáæðabólga með rauðkyrningafjöld, EGPA, falinn fylgisjúkdómur astma? • Sjúkratilfelli •', Læknablaðið, vol. 110, no. 1, pp. 28-32. https://doi.org/10.17992/lbl.2024.01.7770023-72132151615674ddd0439-1b5e-45b5-a164-30ae982ba6a38518073400338126794unpaywall: 10.17992/lbl.2024.01.777https://hdl.handle.net/20.500.11815/7446Publisher Copyright: © 2024 Laeknafelag Islands. All rights reserved.A 72-year-old woman presented to the emergency department due to worsening dyspnea. She had been diagnosed with asthma a year earlier. At arrival, her oxygen saturation was only 84%. During lung auscultation, wheezing was noted over all lung fields. A blood test showed a significant increase in eosinophils in peripheral blood, highest value of 1.4 x 10E9/L. Further investigations in the respiratory ward showed a positive MPO-ANCA, which, together with clinical features of asthma, chronic rhinosinusitis with polyps, mononeuritis multiplex and eosinophilia, led to the diagnosis of eosinophilic granulomatosis with polyangiitis, or what used to be called Churg-Strauss syndrome. Corticosteroid treatment was initiated and subsequently tapered down when treatment with mepolizumab was started, which is an IL-5 inhibitor. Her symptoms quickly became much better. Frequent exacerbations and pulmonary symptoms became things of the past.5329839828-32isinfo:eu-repo/semantics/openAccessEGPAasthmaeosinophilic granulomatosis with polyangiitismepolizumabLung/diagnostic imagingChurg-Strauss Syndrome/complicationsHumansFemaleAgedAsthma/drug therapyGranulomatosis with Polyangiitis/complicationsGeneral Medicine/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article10.17992/lbl.2024.01.777