Háskóli ÍslandsUniversity of IcelandKamble, Nilesh RameshGränz, MarkusPrisner, Thomas F.Sigurdsson, Snorri2020-08-102020-08-1020161359-73451364-548X (eISSN)https://hdl.handle.net/20.500.11815/1960Post-print (lokagerð höfundar)An isoindoline-nitroxide derivative of guanine (G, "G-spin") was shown to bind specifically and effectively to abasic sites in duplex RNAs. Distance measurements on a G-labeled duplex RNA with PELDOR (DEER) showed a strong orientation dependence. Thus, G is a readily synthesized, orientation-selective spin label for "mix and measure" PELDOR experiments.14442-14445eninfo:eu-repo/semantics/openAccessNicotinamide adenine dinucleotideElectron paramagnetic resonanceNucleic acid structureEPR spectroscopyIsoindoline nitroxidesAlcohol dehydrogenaseDistance measurementsAbasic sitesDNADynamicsLitrófsgreiningKjarnsýrurRafeindirinfo:eu-repo/semantics/articleChemical Communications10.1039/C6CC08387K