Jensen, SanneMortensen, Erik L.Skarphedinsson, GudmundurHøjgaard, David RMAHybel, Katja A.Nissen, Judith B.Tord Ivarsson, IvarssonWeidle, BernhardTorp, Nor C.Thomsen, Per H.2025-11-202025-11-202022-11-01Jensen, S, Mortensen, E L, Skarphedinsson, G, Højgaard, D RMA, Hybel, K A, Nissen, J B, Tord Ivarsson, I, Weidle, B, Torp, N C & Thomsen, P H 2022, 'Long- term remission status in pediatric obsessive-compulsive disorder : Evaluating the predictive value of symptom severity after treatment', Psychiatry Research, vol. 317, 114906, pp. 114906. https://doi.org/10.1016/j.psychres.2022.1149060165-178167878862096600f9-7c13-4c0a-9c8b-1b5759879adc8514065889136265194unpaywall: 10.1016/j.psychres.2022.114906https://hdl.handle.net/20.500.11815/6933Funding Information: This work was supported by the Tryg Foundation [grant number 122892] and the Department of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry. Publisher Copyright: © 2022 The Author(s)It is unknown if long-term remission for pediatric obsessive-compulsive disorder (OCD) patients is associated with post-treatment OCD symptom severity. The aim of the present study was to evaluate if post-treatment symptom severity cut-offs can discriminate remitters from non-remitters in pediatric OCD patients during three years of follow-up. All participants (N = 269) from the Nordic Long-term OCD Treatment Study (NordLOTS) undergoing stepped-care treatment were included. Patients were rated with the Clinical Global Impression – Severity Scale (CGI-S) one (n = 186), two (n = 167), and three years (n = 166) after first-line cognitive-behavioral therapy. Post-treatment symptom severity scores as well as percentage reductions during treatment evaluated with the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) were analyzed using receiver operating characteristics according to the CGI-S remission scores (< 2) at follow-up. Post-treatment CY-BOCS severity scores acceptably discriminated remitters from non-remitters at one-year follow-up, but poorly for the two- and three-year follow-up. Severity percentage reduction during treatment did not discriminate remission status acceptably at any follow-up point. Post-treatment OCD symptom severity status seems to have little discriminative value for long-term remission status in pediatric patients. Further research is warranted to detect post-treatment factors of prognostic value.500678114906eninfo:eu-repo/semantics/openAccessChildren and adolescentsChildren's Yale-brown obsessive-compulsive scaleClinical assessmentClinical global impression scaleLong-term studyRemissionStepped-care treatmentHumansCognitive Behavioral TherapyObsessive-Compulsive Disorder/diagnosisChildPsychiatry and Mental HealthBiological Psychiatry/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article10.1016/j.psychres.2022.114906