Háskóli ÍslandsUniversity of IcelandHandsaker, Joseph C.Brown, Steven J.Petrovic, MilosBowling, Frank L.Rajbhandari, SatyanMarple-Horvat, Dilwyn EBoulton, Andrew J.M.Reeves, Neil D.2020-03-202020-03-202019-10Handsaker, J.C. et al., 2019. Combined exercise and visual gaze training improves stepping accuracy in people with diabetic peripheral neuropathy. Journal of Diabetes and Its Complications, 33(10), p.107404.1056-8727https://hdl.handle.net/20.500.11815/1628Publisher's version (útgefin grein)Introduction: Patients with diabetes and diabetic peripheral neuropathy (DPN) place their feet with less accuracy whilst walking, which may contribute to the increased falls-risk. This study examines the effects of a multi-faceted intervention on stepping accuracy, in patients with diabetes and DPN. Methods: Forty participants began the study, of which 29 completed both the pre and post-intervention tests, 8 patients with DPN, 11 patients with diabetes but no neuropathy (D) and 10 healthy controls (C). Accuracy of stepping was measured pre- and post-intervention as participants walked along an irregularly arranged stepping walkway. Participants attended a one-hour session, once a week, for sixteen weeks, involving high-load resistance exercise and visual-motor training. Results: Patients who took part in the intervention improved stepping accuracy (DPN: +45%; D: +36%) (p < 0.05). The diabetic non-intervention (D-NI) group did not display any significant differences in stepping accuracy pre- to post- the intervention period (−7%). Discussion: The improved stepping accuracy observed in patients with diabetes and DPN as a result of this novel intervention, may contribute towards reducing falls-risk. This multi-faceted intervention presents promise for improving the general mobility and safety of patients during walking and could be considered for inclusion as part of clinical treatment programmes.107404eninfo:eu-repo/semantics/openAccessExerciseEye-trackingFallsGaitWalkingHreyfing (heilsurækt)GöngulagSykursýkiSjónskynjuninfo:eu-repo/semantics/articleJournal of Diabetes and its Complications10.1016/j.jdiacomp.2019.07.001