- Opin vísindi
- →
- Háskóli Íslands
- →
- Doktorsritgerðir- HÍ
- →
- Browsing Doktorsritgerðir- HÍ by Subject
JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing Doktorsritgerðir- HÍ by Subject "Læknisfræði"
Now showing items 1-20 of 34
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-06)Acute kidney injury (AKI) is a growing problem worldwide and is associated with high morbidity and mortality. AKI is a known complication following cardiac operations and coronary angiography (CA). Following CA, AKI has been associated with contrast ... -
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-12)Acute kidney injury (AKI) is a common clinical problem both in the hospital and outpatient setting and is associated with increased morbidity and mortality. Chronic kidney disease (CKD) is a risk factor for developing AKI and AKI is a risk factor for ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-08-21)Adenine phosphoribosyltransferase (APRT) deficiency is a rare autosomal recessive disorder of adenine metabolism that results in the generation and renal excretion of large amounts of the poorly soluble 2,8-dihydroxyadenine (DHA), causing kidney ...
-
(University of Iceland, school of health sciences, faculty of medicine, 2020-09)Background: Cognitive impairment is a core feature at all stages of the psychotic illness and significantly predicts functional outcomes. Targeting cognition early is theoretically attractive as a means to reverse the functional impairment before ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019)Aims: The aim of the doctoral project was to develop and assess data extraction and analysis methods specific to the anterior cruciate ligament injury mechanism. The aim of paper I was to evaluate differences in the timing of the peak knee valgus moment ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-11)Germline mutations in BRCA2 increase the risk of breast and ovarian cancer. The BRCA2 protein is involved in maintaining genomic stability through its roles in DNA double strand break repair and protection of stalled replication forks. The BRCA2 gene ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-06-03)Sértækur IgA skortur (sIgAD) er algengasti galli í sértæka ónæmiskerfinu. Gallinn er skilgreindur sem algjör skortur á IgA með eðlilegum IgG og IgM styrk í sermi. Tíðni sjúkdóma sem tengjast óeðlilegu ónæmissvari er hærri hjá sIgAD ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-12-02)Epithelial to mesenchymal transition (EMT) is a developmental trait that is hijacked in some disease conditions such as fibrosis and cancer. In cancer, EMT has been linked to increased invasion and metastasis, and is generally associated with a poor ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-06-04)Lækningamáttur Bláa Lónsins var uppgötvaður af sórasjúklingum skömmu eftir myndun þess og hafa jákvæð áhrif böðunar í lóninu verið staðfest í klínískum rannsóknum. Enn fremur hefur verið sýnt að böðun í lóninu samhliða UVB meðferð sé árangursríkari en ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-09)Introduction and aims: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and its complex pathophysiology is incompletely understood. At the time of beginning of this work, genome-wide association studies (GWAS) on AF had yielded ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-09)The overall aim of this PhD thesis was to cohesively assess the availability and use of electronic genealogy databases and information from cancer registries to construct electronically generated pedigrees for risk assessment in genetic counselling. ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020)Purpose and aims: Multiple sclerosis (MS) is an autoimmune disease that leads to damage in the central nervous system. Although the cause of MS is still unknown, the generally accepted view is that environmental and life-style factors influence the ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-05)The DNA damage response is crucial to maintaining the integrity of DNA and the health of a cell. Unrepaired lesions within the DNA can lead to genomic instability and potentially aid in the formation of diseases such as cancer. Some cancers possess ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-03)Íslenski hesturinn er eini hestastofninn á Íslandi. Hestar voru fluttir hingað við landnám og hafa verið hreinræktaðir síðan. Vegna landfræðilegrar einangrunar er stofninn berskjaldaður fyrir mörgum sjúkdómsvöldum sem herja á hesta í öðrum löndum. ...
-
(University of Iceland, School of Humanities, Faculty of History and Philosophy, 2022-05-03)This thesis explores the meaning of medicine and considers ethical challenges that arise when medicine's limits are tested as it enters new grounds. The methodology and argumentation used in the thesis can be described as a two-step process. In the ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2021)Markmið: Að kanna áhættuþætti fyrir fæðingu mikilla þungbura (fæðingarþyngd ≥5000 g) og hugsanlegar afleiðingar þess fyrir móður og barn (grein 1). Að meta efnaskipti mikilla þungbura með því að skoða mynstur þeirra amínósýra og acylkarnitína sem mæld ...
-
(2021-04)A better understanding of normal organ development can give deeper insight into which genes are harnessed by aberrant cells during cancer formation and progression. In my thesis, I have investigated two seemingly different, however, related, developmental ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-08)The microenvironment is increasingly being recognized as a key player in supporting cancer progression. Therefore, investigating heterotypic interactions between cancer cells and their microenvironment is important for improving our understanding ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-06)Aims: The aims of this thesis were: (1) to describe functioning and contextual factors of community-dwelling stroke survivors 1-2 years after their first stroke, based on the International Classification of Functioning, Disability and Health (ICF) ...
-
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-06-15)Breast cancer is the most common type of cancer in women worldwide. It is also a highly heterogeneous disease that is characterized by an array of genetic rearrangements, including copy number alterations (CNA), translocations, inversions, ...
Now showing items 1-20 of 34