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Browsing Doktorsritgerðir- HÍ by Department "Faculty of Medicine (UI)"
Now showing items 1-20 of 88
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-06)Acute kidney injury (AKI) is a growing problem worldwide and is associated with high morbidity and mortality. AKI is a known complication following cardiac operations and coronary angiography (CA). Following CA, AKI has been associated with contrast ... -
(University of Iceland, School of Health Sciences, Faculty of Medicine, 2017-01-06)In line with advances in surgery, perioperative care, and intensive care, the outcome in patients treated for cardiovascular disease has improved. Open-heart surgery is common in most western countries and, in line with the general ageing of populations, ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-12)Acute kidney injury (AKI) is a common clinical problem both in the hospital and outpatient setting and is associated with increased morbidity and mortality. Chronic kidney disease (CKD) is a risk factor for developing AKI and AKI is a risk factor for ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-08-21)Adenine phosphoribosyltransferase (APRT) deficiency is a rare autosomal recessive disorder of adenine metabolism that results in the generation and renal excretion of large amounts of the poorly soluble 2,8-dihydroxyadenine (DHA), causing kidney ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-04-10)Background: Schizophrenia is a chronic serious mental disorder with prevalence close to 0.7%. Early symptoms of schizophrenia generally appear in late adolescence or the early twenties. The prognosis is usually worse in cases of early onset. The ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-09-21)The geographic remoteness of the Faroe Islands makes the archipelago an ideal location for research on bacterial carriage, their clonality, and vaccine studies. However, previous studies are lacking and the limited availability of necessary data has ...
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(University of Iceland, school of health sciences, faculty of medicine, 2020-09)Background: Cognitive impairment is a core feature at all stages of the psychotic illness and significantly predicts functional outcomes. Targeting cognition early is theoretically attractive as a means to reverse the functional impairment before ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-02-19)Bakgrunnur: Framfarir í meðferð alvarlega veikra sjúklinga og hækkaður lífaldur hefur leitt til þess að fleira fólk lifir nú af bráð og alvarleg veikindi en áður. Afleiðingar veikindanna ásamt gjörgæslulegunni geta haft áhrif á líkamlegt og sálrænt ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-04)Aims: The purpose of this doctoral research is to investigate the treatment of coronary artery disease in groups that are underrepresented in randomized clinical trials using the SWEDEHEART registry. The more specific aims are: i) to compare the outcomes ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019)Aims: The aim of the doctoral project was to develop and assess data extraction and analysis methods specific to the anterior cruciate ligament injury mechanism. The aim of paper I was to evaluate differences in the timing of the peak knee valgus moment ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-11)Germline mutations in BRCA2 increase the risk of breast and ovarian cancer. The BRCA2 protein is involved in maintaining genomic stability through its roles in DNA double strand break repair and protection of stalled replication forks. The BRCA2 gene ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-02)The focus has shifted in recent years from clinical towards a biological definition of Alzheimer’s disease (AD), as pathophysiological changes precede the clinical symptoms by decades. In vivo brain imaging and cerebrospinal fluid (CSF) biomarkers have ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023)Inngangur: Íþyngjandi dagsyfja er einkenni sem hefur flókið samband við svefn, lífstíl, andlega- og líkamlega heilsu einstaklinga. Kæfisvefn er algengasti sjúkdómurinn sem veldur dagsyfju. Epworth Syfjuskali (ESS) og er stuttur spurningalisti sem ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-11-16)ATG7, an essential protein for cellular homeostasis, plays a pivotal role in regulating autophagy. The autophagy process ensures the degradation and recycling of cellular components for proper cell function. ATG7 facilitates the lipidation of ATG8 ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2017-02-03)Background and aims: Worldwide chronic musculoskeletal (MSK) pain is a prevalent problem constituting a considerable societal burden. The aim was to investigate the prevalence of chronic MSK pain conditions in Iceland and the potential impact on physical ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-06-03)Sértækur IgA skortur (sIgAD) er algengasti galli í sértæka ónæmiskerfinu. Gallinn er skilgreindur sem algjör skortur á IgA með eðlilegum IgG og IgM styrk í sermi. Tíðni sjúkdóma sem tengjast óeðlilegu ónæmissvari er hærri hjá sIgAD ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-11)Inngangur. Þrátt fyrir að næstum öld sé liðin frá uppgötvun penisillíns og að langt sé liðið síðan bólusetningar hófust gegn Streptococcus pneumoniae (pneumokokkum), algengasta orsakavaldi lungnabólgu fullorðinna, er enn um algengan og alvarlegan sjúkdóm ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-05-27)Oral anticoagulants (OACs) are among the most commonly used medication worldwide. Vitamin K antagonists, such as warfarin, were the only available oral anticoagulants for over 60 years. However, in the 2010s, novel direct oral anticoagulants (DOACs) ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-12-02)Epithelial to mesenchymal transition (EMT) is a developmental trait that is hijacked in some disease conditions such as fibrosis and cancer. In cancer, EMT has been linked to increased invasion and metastasis, and is generally associated with a poor ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-05-24)Breast cancer is the leading cause of cancer deaths among women in Iceland and worldwide. Epithelial-mesenchymal transition (EMT) is a cellular developmental process where epithelial cells assume mesenchymal-like phenotypes through degradation of the ...
Now showing items 1-20 of 88