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Fletta eftir deild "Verkfræðideild (HR)"

Fletta eftir deild "Verkfræðideild (HR)"

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    Assessing cardiovascular risks from a mid-thigh CT image: A tree-based machine learning approach using radiodensitometric distributions 
    Ricciardi, Carlo; Edmunds, Kyle; Recenti, Marco; Sigurdsson, Sigurdur; Gudnason, Vilmundur; Carraro, Ugo; Gargiulo, Paolo (Springer Science and Business Media LLC, 2020-02-18)
    The nonlinear trimodal regression analysis (NTRA) method based on radiodensitometric CT distributions was recently developed and assessed for the quantification of lower extremity function and nutritional parameters in aging subjects. However, the use ...
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    Current Status and Future Prospects of Genome-Scale Metabolic Modeling to Optimize the Use of Mesenchymal Stem Cells in Regenerative Medicine 
    Sigmarsdóttir, Þóra; McGarrity, Sarah; Rolfsson, Óttar; Yurkovich, James T.; Sigurjónsson, Ólafur E. (Frontiers Media SA, 2020-03-31)
    Mesenchymal stem cells are a promising source for externally grown tissue replacements and patient-specific immunomodulatory treatments. This promise has not yet been fulfilled in part due to production scaling issues and the need to maintain the correct ...
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    Effects of amotosalen treatment on human platelet lysate bioactivity: A proof-of-concept study 
    Christensen, Christian; Jonsdottir-Buch, Sandra Mjoll; Sigurjonsson, Olafur (Public Library of Science (PLoS), 2020-04-15)
    Background Clinical application of mesenchymal stromal cells (MSCs) usually requires an in vitro expansion step to reach clinically relevant numbers. In vitro cell expansion necessitates supplementation of basal mammalian cell culture medium with growth ...
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    Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis 
    Ólafsdóttir, Þórunn Ásta; Theódórs, Fannar; Bjarnadóttir, Kristbjörg; Björnsdóttir, Unnur Steina; Agustsdottir, Arna B.; Stefánsson, Ólafur A.; Ivarsdottir, Erna; Sigurðsson, Jón K.; Benónísdóttir, Stefanía; Eyjólfsson, Guðmundur I.; Gíslason, Davíð; Gislason, Thorarinn; Guðmundsdóttir, Steinunn; Gylfason, Arnaldur; Halldórsson, Bjarni; Halldorsson, Gisli; Júlíusdóttir, Þórhildur; Kristinsdottir, Anna M.; Lúðvíksdóttir, Dóra; Ludviksson, Bjorn; Másson, Gísli; Norland, Kristjan; Onundarson, Pall; Olafsson, Isleifur; Sigurdardottir, Olof; Stefánsdóttir, Lilja; Sveinbjörnsson, Garðar; Tragante do O, Vinicius; Gudbjartsson, Daniel; Þorleifsson, Guðmar; sulem, patrick; Thorsteinsdottir, Unnur; Norddahl, Guðmundur L.; Jonsdottir, Ingileif; Stefansson, Kari (Springer Science and Business Media LLC, 2020-01-20)
    Asthma is one of the most common chronic diseases affecting both children and adults. We report a genome-wide association meta-analysis of 69,189 cases and 702,199 controls from Iceland and UK biobank. We find 88 asthma risk variants at 56 loci, 19 ...
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    Fabrication and characterization of Si1−xGex nanocrystals in as-grown and annealed structures: a comparative study 
    Sultan, Muhammad Taha; Maraloiu, Adrian Valentin; Stavarache, Ionel; Gudmundsson, Jon Tomas; Manolescu, Andrei; Teodorescu, Valentin Serban; Ciurea, Magdalena Lidia; Svavarsson, Halldor (Beilstein Institut, 2019-09-17)
    Multilayer structures comprising of SiO2/SiGe/SiO2 and containing SiGe nanoparticles were obtained by depositing SiO2 layers using reactive direct current magnetron sputtering (dcMS), whereas, Si and Ge were co-sputtered using dcMS and high-power impulse ...
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    Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank 
    Ólafsdóttir, Thorhildur; Thorleifsson, Gudmar; sulem, patrick; Stefánsson, Ólafur A.; Medek, Helga; Olafsson, Karl; Ingþórsson, Orri; Guðmundsson, Valur; Jonsdottir, Ingileif; Halldorsson, Gisli; Kristjansson, Ragnar; Frigge, Michael L.; Stefánsdóttir, Lilja; Sigurðsson, Jón K.; Oddsson, Asmundur; Sigurðsson, Ásgeir; Eggertsson, Hannes P.; Melsted, Páll; Halldórsson, Bjarni; Lund, Sigrún Helga; Styrkarsdottir, Unnur; Steinthorsdottir, Valgerdur; Gudmundsson, Julius; Holm, Hilma; Tragante do O, Vinicius; Asselbergs, Folkert; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Jónsdóttir, Kristín; Rafnar, Thorunn; Stefansson, Kari (Springer Science and Business Media LLC, 2020-03-17)
    Pelvic organ prolapse (POP) is a downward descent of one or more of the pelvic organs, resulting in a protrusion of the vaginal wall and/or uterus. We performed a genome-wide association study of POP using data from Iceland and the UK Biobank, a total ...
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    GraphTyper2 enables population-scale genotyping of structural variation using pangenome graphs 
    Eggertsson, Hannes; Kristmundsdóttir, Snædís; Beyter, Doruk; Jónsson, Hákon; Skúladóttir, Ástrós; Hardarson, Marteinn; Gudbjartsson, Daniel; Stefansson, Kari; Halldórsson, Bjarni; Melsted, Páll (Springer Science and Business Media LLC, 2019-11-27)
    Analysis of sequence diversity in the human genome is fundamental for genetic studies. Structural variants (SVs) are frequently omitted in sequence analysis studies, although each has a relatively large impact on the genome. Here, we present GraphTyper2, ...
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    Human Embryonic-Derived Mesenchymal Progenitor Cells (hES-MP Cells) are Fully Supported in Culture with Human Platelet Lysates 
    Jonsdottir-Buch, Sandra Mjoll; Gunnarsdottir, Kristbjorg; Sigurjonsson, Olafur (MDPI AG, 2020-07-20)
    Human embryonic stem cell-derived mesenchymal progenitor (hES-MP) cells are mesenchymal-like cells, derived from human embryonic stem cells without the aid of feeder cells. They have been suggested as a potential alternative to mesenchymal stromal cells ...
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    A probabilistic geologic model of the Krafla geothermal system constrained by gravimetric data 
    Scott, Samuel; Covell, Cari; Júlíusson, Egill; Valfells, Agust; Newson, Juliet; Hrafnkelsson, Birgir; Pálsson, Halldór; Gudjónsdóttir, María (Springer Science and Business Media LLC, 2019-09-24)
    The quantitative connections between subsurface geologic structure and measured geophysical data allow 3D geologic models to be tested against measurements and geophysical anomalies to be interpreted in terms of geologic structure. Using a Bayesian ...
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    Simulation-based appraisal of tax-induced electro-mobility promotion in Iceland and prospects for energy-economic development 
    Shafiei, Ehsan; Davidsdottir, Brynhildur; Stefansson, Hlynur; Asgeirsson, Eyjolfur Ingi; Fazeli, Reza; Gestsson, Marías Halldór; Leaver, Jonathan (Elsevier BV, 2019-10)
    Transition to electric vehicles (EVs) requires multidimensional policy measures incorporating vehicle fleets, energy systems, consumer behaviours, and socio-economic developments. The main objective of this paper is to evaluate the implications of a ...
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    Tailoring microstructure and stress through energetic ion bombardment: A molecular dynamic simulation 
    Kateb, Movaffaq; Gudmundsson, Jon Tomas; Ingvarsson, Snorri (2020)
    We studied high power impulse magnetron sputtering (HiPIMS) and different substrate bias for the epitaxial growth of Cu film on Cu (111) substrate by molecular dynamics simulation. We assumed a fully ionized deposition flux to represent the high ...