There are three prolyl hydroxylases (PHD1, 2 and 3) that regulate the hypoxia-inducible factors (HIFs), the master transcriptional regulators that respond to changes in intracellular O(2) tension. In high O(2) tension (normoxia) the PHDs hydroxylate ...

It is well established that rootless cones and associated deposits are the result of explosive interactions between lava flows and environmental water, but there is substantial uncertainty about the dynamics of rootless eruptions, particularly the ...

For many migratory species, migration can represent a significant part of the annual cycle and the strategies used to move between the breeding and non-breeding areas vary considerably. Weather conditions are important during migration, particularly ...

Breast cancer (BC) is the most prevalent type of cancer in women in western countries. BC mortality has not declined despite early detection by screening, indicating the need for better informed treatment decisions. Therefore, a novel noninvasive ...

1-D models were calculated for the velocity of shear waves, polarized vertically (SV) and horizontally (SH) from dispersed Rayleigh and Love surface waves. These had been recorded in Iceland by the ICEMELT broad-band seismic network, with about half ...

Líðan leikskólakennara og leiðbeinenda, svo og aðbúnaður á vinnustað, er meðal þess sem getur haft áhrif á leikskólabörn og þroskaferil þeirra. Því er brýnt að rannsaka líðan þessara starfshópa og hvaða þættir í vinnuumhverfinu styðja við eða draga úr ...

Using a combination of extended X-ray absorption fine structure measurements, stochastic quenching (SQ) calculations and Voronoi tessellation analysis, the local atomic environments in thin films of amorphous SmxCo1−x (x= 0.10, 0.22 and 0.35) are ...

Timescales of magma transfer and differentiation processes can be estimated when the magma differentiation mechanism is known. When conventional major and trace element analyses fail to distinguish between various processes of magma differentiation, ...

Background: To determine the longitudinal construct validity of assessing hand OA progression on digital photographs over 7 years compared with progression determined from radiographs, clinical features and change in symptoms. Methods: Participants ...

Background: More than 500 million people worldwide live within exposure range of an active volcano and children are a vulnerable subgroup of such exposed populations. However, studies on the effects of volcanic eruptions on children’s health beyond the ...