dc.contributor.author | Taddei, Cristina |
dc.contributor.author | Jackson, Rod |
dc.contributor.author | Zhou, Bin |
dc.contributor.author | Bixby, Honor |
dc.contributor.author | Danaei, Goodarz |
dc.contributor.author | Di Cesare, Mariachiara |
dc.contributor.author | Kuulasmaa, Kari |
dc.contributor.author | Hajifathalian, Kaveh |
dc.contributor.author | Bentham, James |
dc.contributor.author | Bennett, James E. |
dc.contributor.author | Aekplakorn, Wichai |
dc.contributor.author | Cifkova, Renata |
dc.contributor.author | Dallongeville, Jean |
dc.contributor.author | Debacquer, Dirk |
dc.contributor.author | Giampaoli, Simona |
dc.contributor.author | Guðnason, Vilmundur G. |
dc.contributor.author | Khang, Young Ho |
dc.contributor.author | Laatikainen, Tiina |
dc.contributor.author | Mann, Jimi |
dc.contributor.author | Marques-Vidal, Pedro |
dc.contributor.author | Mensah, Georgea |
dc.contributor.author | Müller-Nurasyid, Martina |
dc.contributor.author | Ninomiya, Toshiharu |
dc.contributor.author | Petkeviciene, Janina |
dc.contributor.author | Rodríguez-Artalejo, Fernando |
dc.contributor.author | Servais, Jennifer |
dc.contributor.author | Söderberg, Stefan |
dc.contributor.author | Stavreski, Bill |
dc.contributor.author | Wilsgaard, Tom |
dc.contributor.author | Zdrojewski, Tomasz |
dc.contributor.author | Zhao, Dong |
dc.contributor.author | Stevens, Gretchen A. |
dc.contributor.author | Savin, Stefan |
dc.contributor.author | Cowan, Melanie J. |
dc.contributor.author | Riley, Leanne M. |
dc.contributor.author | Ezzati, Majid |
dc.contributor.author | Adams, Robert J. |
dc.contributor.author | Ahrens, Wolfgang |
dc.contributor.author | Amouyel, Philippe |
dc.contributor.author | Amuzu, Antoinette |
dc.contributor.author | Anderssen, Sigmund A. |
dc.contributor.author | Ariansen, Inger |
dc.contributor.author | Arveiler, Dominique |
dc.contributor.author | Aspelund, Thor |
dc.contributor.author | Auvinen, Juha |
dc.contributor.author | Avdicová, Mária |
dc.contributor.author | Banach, Maciej |
dc.contributor.author | Bandosz, Piotr |
dc.contributor.author | Banegas, José R. |
dc.contributor.author | Barbagallo, Carlo M. |
dc.contributor.author | Bata, Iqbal |
dc.contributor.author | Baur, Louise A. |
dc.contributor.author | Beaglehole, Robert |
dc.contributor.author | Bernotiene, Gailute |
dc.contributor.author | Bi, Yufang |
dc.contributor.author | Bienek, Asako |
dc.contributor.author | Björkelund, Cecilia |
dc.contributor.author | Bo, Simona |
dc.contributor.author | Boehm, Bernhard O. |
dc.contributor.author | Bonaccio, Marialaura |
dc.contributor.author | Bongard, Vanina |
dc.contributor.author | Borchini, Rossana |
dc.contributor.author | Borghs, Herman |
dc.contributor.author | Breckenkamp, Juergen |
dc.contributor.author | Brenner, Hermann |
dc.contributor.author | Bruno, Graziella |
dc.contributor.author | Busch, Markusa |
dc.contributor.author | Cabreradeleón, Antonio |
dc.contributor.author | Capuano, Vincenzo |
dc.contributor.author | Casanueva, Felipe F. |
dc.contributor.author | Casas, Juan Pablo |
dc.contributor.author | Caserta, Carmelo A. |
dc.contributor.author | Censi, Laura |
dc.contributor.author | Chen, Fangfang |
dc.contributor.author | Chen, Shuohua |
dc.contributor.author | Chirlaque, María Dolores |
dc.contributor.author | Cho, Belong |
dc.contributor.author | Cho, Yumi |
dc.contributor.author | Chudek, Jerzy |
dc.contributor.author | Claessens, Frank |
dc.contributor.author | Clarke, Janine |
dc.contributor.author | Clays, Els |
dc.contributor.author | Cooper, Cyrus |
dc.contributor.author | Costanzo, Simona |
dc.contributor.author | Cottel, Dominique |
dc.contributor.author | Cowell, Chris |
dc.contributor.author | Crujeiras, Ana B. |
dc.contributor.author | Cui, Liufu |
dc.contributor.author | D'Arrigo, Graziella |
dc.contributor.author | Dauchet, Luc |
dc.contributor.author | De Backer, Guy |
dc.contributor.author | De Bacquer, Dirk |
dc.contributor.author | De Gaetano, Giovanni |
dc.contributor.author | De Henauw, Stefaan |
dc.contributor.author | De Smedt, Delphine |
dc.contributor.author | Dennison, Elaine |
dc.contributor.author | Deschamps, Valérie |
dc.contributor.author | Dicastelnuovo, Augusto |
dc.contributor.author | Dobson, Annette J. |
dc.contributor.author | Donfrancesco, Chiara |
dc.contributor.author | Döring, Angela |
dc.contributor.author | Drygas, Wojciech |
dc.contributor.author | Du, Yong |
dc.contributor.author | Dziankowska-Zaborszczyk, Elzbieta |
dc.contributor.author | Eggertsen, Robert |
dc.contributor.author | Ekelund, Ulf |
dc.contributor.author | Elosua, Roberto |
dc.contributor.author | Eriksson, Johan G. |
dc.contributor.author | Evans, Alun |
dc.contributor.author | Faeh, David |
dc.contributor.author | Felix-Redondo, Francisco J. |
dc.contributor.author | Fernández-Bergés, Daniel |
dc.contributor.author | Ferrari, Marika |
dc.contributor.author | Ferrieres, Jean |
dc.contributor.author | Finn, Joseph D. |
dc.contributor.author | Forslund, Ann Sofie |
dc.contributor.author | Forsner, Maria |
dc.contributor.author | Frontera, Guillermo |
dc.contributor.author | Fujita, Yuki |
dc.contributor.author | Gaciong, Zbigniew |
dc.contributor.author | Galvano, Fabio |
dc.contributor.author | Gao, Jingli |
dc.contributor.author | Garcia-De-La-Hera, Manoli |
dc.contributor.author | Garnett, Sarahp |
dc.contributor.author | Gaspoz, Jean Michel |
dc.contributor.author | Gasull, Magda |
dc.contributor.author | Gates, Louise |
dc.contributor.author | Gianfagna, Francesco |
dc.contributor.author | Gill, Tiffany K. |
dc.contributor.author | Giovannelli, Jonathan |
dc.contributor.author | Goltzman, David |
dc.contributor.author | Gonzalezgross, Marcela |
dc.contributor.author | Gottrand, Frederic |
dc.contributor.author | Graff-Iversen, Sidsel |
dc.contributor.author | Grafnetter, Dušan |
dc.contributor.author | Gregor, Ronald D. |
dc.contributor.author | Grodzicki, Tomasz |
dc.contributor.author | Grosso, Giuseppe |
dc.contributor.author | Gruden, Grabriella |
dc.contributor.author | Gu, Dongfeng |
dc.contributor.author | Guallar-Castillón, Pilar |
dc.contributor.author | Gudmundsson, Elias F. |
dc.contributor.author | Guessous, Idris |
dc.contributor.author | Gunnlaugsdottir, Johanna |
dc.contributor.author | Gutzwiller, Felix |
dc.contributor.author | Hardy, Rebecca |
dc.contributor.author | Hata, Jun |
dc.contributor.author | Haugsgjerd, Teresa |
dc.contributor.author | Hayes, Alison J. |
dc.contributor.author | He, Jiang |
dc.contributor.author | He, Yuna |
dc.contributor.author | Herrala, Sauli |
dc.contributor.author | Tapanihihtaniemi, Ilpo |
dc.contributor.author | Hobbs, Michael |
dc.contributor.author | Hopman, Wilma M. |
dc.contributor.author | Maríahuerta, José |
dc.contributor.author | Huybrechts, Inge |
dc.contributor.author | Iacoviello, Licia |
dc.contributor.author | Iannone, Anna G. |
dc.contributor.author | Ikeda, Nayu |
dc.contributor.author | Iwasaki, Masanori |
dc.contributor.author | Jamrozik, Konrad |
dc.contributor.author | Janszky, Imre |
dc.contributor.author | Jarvelin, Marjo Riitta |
dc.contributor.author | Jasienska, Grazyna |
dc.contributor.author | Jennings, Garry |
dc.contributor.author | Jeong, Seung Lyeal |
dc.contributor.author | Qiangjiang, Chao |
dc.contributor.author | Joffres, Michel |
dc.contributor.author | Jokelainen, Jari J. |
dc.contributor.author | Jonas, Jost B. |
dc.contributor.author | Jóźwiak, Jacek |
dc.contributor.author | Kajantie, Eero O. |
dc.contributor.author | Kauhanen, Jussi |
dc.contributor.author | Keil, Ulrich |
dc.contributor.author | Keinänen-Kiukaanniemi, Sirkka |
dc.contributor.author | Kersting, Mathilde |
dc.contributor.author | Kiechl-Kohlendorfer, Ursula |
dc.contributor.author | Kiechl, Stefan |
dc.contributor.author | Kim, Jeongseon |
dc.contributor.author | Kim, Yeon Yong |
dc.contributor.author | Klumbiene, Jurate |
dc.contributor.author | Knoflach, Michael |
dc.contributor.author | Ko, Stephanie |
dc.contributor.author | Kolle, Elin |
dc.contributor.author | Korpelainen, Raija |
dc.contributor.author | Koskinen, Seppo |
dc.contributor.author | Kouda, Katsuyasu |
dc.contributor.author | Kratzer, Wolfgang |
dc.contributor.author | Kriemler, Susi |
dc.contributor.author | Krokstad, Steinar |
dc.contributor.author | Kujala, Urhom |
dc.contributor.author | Kurjata, Pawel |
dc.contributor.author | Hinglam, Tai |
dc.contributor.author | Lanska, Vera |
dc.contributor.author | Lappas, Georg |
dc.contributor.author | Laugsand, Lars E. |
dc.contributor.author | Lee, Jeonghee |
dc.contributor.author | Lehtimäki, Terho |
dc.contributor.author | Li, Yanping |
dc.contributor.author | Lilly, Christa L. |
dc.contributor.author | Lin, Xu |
dc.contributor.author | Lind, Lars |
dc.contributor.author | Lissner, Lauren |
dc.contributor.author | Liu, Jing |
dc.contributor.author | Lopez-Garcia, Esther |
dc.contributor.author | Lorbeer, Roberto |
dc.contributor.author | Eugeniolozano, José |
dc.contributor.author | Luksiene, Dalia |
dc.contributor.author | Lundqvist, Annamari |
dc.contributor.author | Lundqvist, Robert |
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dc.contributor.author | Maggi, Stefania |
dc.contributor.author | Magliano, Dianna J. |
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dc.contributor.author | Manzato, Enzo |
dc.contributor.author | Mathiesen, Ellisiv B. |
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dc.contributor.author | Mossakowska, Malgorzata |
dc.contributor.author | Muiesan, Maria L. |
dc.contributor.author | Mursu, Jaakko |
dc.contributor.author | Nakamura, Harunobu |
dc.contributor.author | Námešná, Jana |
dc.contributor.author | Matthias, M. |
dc.contributor.author | Marianavarrete-Muñoz, Eva |
dc.contributor.author | Neal, William A. |
dc.contributor.author | Nenko, Ilona |
dc.contributor.author | Niiranen, Teemu J. |
dc.contributor.author | Ning, Guang |
dc.contributor.author | Noale, Marianna |
dc.contributor.author | Norie, Sawada |
dc.contributor.author | Noto, Davide |
dc.contributor.author | O'Neill, Terence |
dc.contributor.author | O'Reilly, Dermot |
dc.contributor.author | Oh, Kyungwon |
dc.contributor.author | Olafsson, Örn |
dc.contributor.author | Michelpaccaud, Fred |
dc.contributor.author | Pajak, Andrzej |
dc.contributor.author | Palmieri, Luigi |
dc.contributor.author | Panza, Francesco |
dc.contributor.author | Parnell, Winsome R. |
dc.contributor.author | Peltonen, Markku |
dc.contributor.author | Peters, Annette |
dc.contributor.author | Petersmann, Astrid |
dc.contributor.author | Pigeot, Iris |
dc.contributor.author | Pilotto, Lorenza |
dc.contributor.author | Piwonska, Aleksandra |
dc.contributor.author | Plans-Rubió, Pedro |
dc.contributor.author | Porta, Miquel |
dc.contributor.author | Price, Jacqueline F. |
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dc.contributor.author | Radisauskas, Ricardas |
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dc.contributor.author | Ramos, Rafel |
dc.contributor.author | Redon, Josep |
dc.contributor.author | Rigo, Fernando |
dc.contributor.author | Rodriguez-Perez, Maríadel Cristo |
dc.contributor.author | Romaguera, Dora |
dc.contributor.author | Ronkainen, Kimmo |
dc.contributor.author | Rosengren, Annika |
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dc.contributor.author | Salanave, Benoit |
dc.contributor.author | Salmerón, Diego |
dc.contributor.author | Salomaa, Veikko |
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dc.contributor.author | Stehle, Peter |
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dc.contributor.author | Stöckl, Doris |
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dc.contributor.author | Tsugane, Shoichiro |
dc.contributor.author | Tuomainen, Tomi Pekka |
dc.contributor.author | Tuomilehto, Jaakko |
dc.contributor.author | Tzourio, Christophe |
dc.contributor.author | Uusitalo, Hannu M.T. |
dc.contributor.author | Vanherck, Koen |
dc.contributor.author | Vanderschueren, Dirk |
dc.contributor.author | Vanuzzo, Diego |
dc.contributor.author | Vatten, Lars |
dc.contributor.author | Vega, Tomas |
dc.contributor.author | Veronesi, Giovanni |
dc.contributor.author | Vioque, Jesus |
dc.contributor.author | Virtanen, Jyrkik |
dc.contributor.author | Visvikis-Siest, Sophie |
dc.contributor.author | Vollenweider, Peter |
dc.contributor.author | Voutilainen, Sari |
dc.contributor.author | Vrijheid, Martine |
dc.contributor.author | Wagner, Aline |
dc.contributor.author | Wagner, Anne |
dc.contributor.author | Wang, Ming Dong |
dc.contributor.author | Wang, Qian |
dc.contributor.author | Xingwang, Ya |
dc.contributor.author | Wannamethee, S. Goya |
dc.contributor.author | Wei, Wenbin |
dc.contributor.author | Wiecek, Andrzej |
dc.contributor.author | Willeit, Johann |
dc.contributor.author | Willeit, Peter |
dc.contributor.author | Wojtyniak, Bogdan |
dc.contributor.author | Wong, Andrew |
dc.contributor.author | Woodward, Mark |
dc.contributor.author | Giwercmanwu, Aleksander |
dc.contributor.author | Wu, Frederick C. |
dc.contributor.author | Wu, Shouling |
dc.contributor.author | Xu, Haiquan |
dc.contributor.author | Xu, Liang |
dc.contributor.author | Yan, Weili |
dc.contributor.author | Yang, Xiaoguang |
dc.contributor.author | Ye, Xingwang |
dc.contributor.author | Yoshihara, Akihiro |
dc.contributor.author | Zambon, Sabina |
dc.contributor.author | Zhao, Wenhua |
dc.date.accessioned | 2022-07-28T01:03:09Z |
dc.date.available | 2022-07-28T01:03:09Z |
dc.date.issued | 2020-02-01 |
dc.identifier.citation | Taddei , C , Jackson , R , Zhou , B , Bixby , H , Danaei , G , Di Cesare , M , Kuulasmaa , K , Hajifathalian , K , Bentham , J , Bennett , J E , Aekplakorn , W , Cifkova , R , Dallongeville , J , Debacquer , D , Giampaoli , S , Guðnason , V G , Khang , Y H , Laatikainen , T , Mann , J , Marques-Vidal , P , Mensah , G , Müller-Nurasyid , M , Ninomiya , T , Petkeviciene , J , Rodríguez-Artalejo , F , Servais , J , Söderberg , S , Stavreski , B , Wilsgaard , T , Zdrojewski , T , Zhao , D , Stevens , G A , Savin , S , Cowan , M J , Riley , L M , Ezzati , M , Adams , R J , Ahrens , W , Amouyel , P , Amuzu , A , Anderssen , S A , Ariansen , I , Arveiler , D , Aspelund , T , Auvinen , J , Avdicová , M , Banach , M , Bandosz , P , Banegas , J R , Barbagallo , C M , Bata , I , Baur , L A , Beaglehole , R , Bernotiene , G , Bi , Y , Bienek , A , Björkelund , C , Bo , S , Boehm , B O , Bonaccio , M , Bongard , V , Borchini , R , Borghs , H , Breckenkamp , J , Brenner , H 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, Virtanen , J , Visvikis-Siest , S , Vollenweider , P , Voutilainen , S , Vrijheid , M , Wagner , A , Wagner , A , Wang , M D , Wang , Q , Xingwang , Y , Wannamethee , S G , Wei , W , Wiecek , A , Willeit , J , Willeit , P , Wojtyniak , B , Wong , A , Woodward , M , Giwercmanwu , A , Wu , F C , Wu , S , Xu , H , Xu , L , Yan , W , Yang , X , Ye , X , Yoshihara , A , Zambon , S & Zhao , W 2020 , ' National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio : A pooled analysis of 458 population-based studies in Asian and Western countries ' , International Journal of Epidemiology , vol. 49 , no. 1 , pp. 173-192 . https://doi.org/10.1093/ije/dyz099 |
dc.identifier.issn | 0300-5771 |
dc.identifier.other | 38450912 |
dc.identifier.other | f461d68d-f21e-4665-bed7-01fae0b35cbd |
dc.identifier.other | 85074478745 |
dc.identifier.other | 31321439 |
dc.identifier.uri | https://hdl.handle.net/20.500.11815/3303 |
dc.description | This work was supported by the Wellcome Trust (grant numbers 101506/Z/13/Z and Research Training Fellowship 203616/Z/16/Z). R.C. acknowledges funding from the Ministry of Health of the Czech Republic (grant number 15-27109A). Publisher Copyright: © 2019 The Author(s) 2019. Published by Oxford University Press on behalf of the International Epidemiological Association. |
dc.description.abstract | Background: Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to compare trends in total, HDL and non-HDL cholesterol and the total-to-HDL cholesterol ratio in Asian and Western countries. Methods: We pooled 458 population-based studies with 82.1 million participants in 23 Asian and Western countries. We estimated changes in mean total, HDL and non-HDL cholesterol and mean total-to-HDL cholesterol ratio by country, sex and age group. Results: Since ∼1980, mean TC increased in Asian countries. In Japan and South Korea, the TC rise was due to rising HDL cholesterol, which increased by up to 0.17 mmol/L per decade in Japanese women; in China, it was due to rising non-HDL cholesterol. TC declined in Western countries, except in Polish men. The decline was largest in Finland and Norway, at ∼0.4 mmol/L per decade. The decline in TC in most Western countries was the net effect of an increase in HDL cholesterol and a decline in non-HDL cholesterol, with the HDL cholesterol increase largest in New Zealand and Switzerland. Mean total-to-HDL cholesterol ratio declined in Japan, South Korea and most Western countries, by as much as ∼0.7 per decade in Swiss men (equivalent to ∼26% decline in coronary heart disease risk per decade). The ratio increased in China. Conclusions: HDL cholesterol has risen and the total-to-HDL cholesterol ratio has declined in many Western countries, Japan and South Korea, with only a weak correlation with changes in TC or non-HDL cholesterol. |
dc.format.extent | 20 |
dc.format.extent | 691094 |
dc.format.extent | 173-192 |
dc.language.iso | en |
dc.relation.ispartofseries | International Journal of Epidemiology; 49(1) |
dc.rights | info:eu-repo/semantics/openAccess |
dc.subject | Blóðfita |
dc.subject | Kólesteról |
dc.subject | Blood lipids |
dc.subject | HDL cholesterol |
dc.subject | LDL cholesterol |
dc.subject | Multi-country study |
dc.subject | Total cholesterol |
dc.subject | Epidemiology |
dc.title | National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio : A pooled analysis of 458 population-based studies in Asian and Western countries |
dc.type | /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article |
dc.description.version | Peer reviewed |
dc.identifier.doi | 10.1093/ije/dyz099 |
dc.relation.url | http://www.scopus.com/inward/record.url?scp=85074478745&partnerID=8YFLogxK |
dc.contributor.department | Faculty of Medicine |