The treatment of acute lymphoblastic leukemia (ALL) is frequently complicated by toxicity, including venous thromboembolism (VTE) affecting roughly 8% of patients. VTE can lead to post-thrombotic syndrome (PTS), a group of signs and symptoms developed ...
PURPOSE: The purpose of this study was to examine the differences of optic nerve subarachnoid space (ONSAS) volume in patients with normal tension glaucoma (NTG) and healthy controls in different body positions. METHODS: Eight patients with NTG and ...
Recht, Michael P.; Donoso-Bach, Lluís; Brkljačić, Boris; Chandarana, Hersh; Jankharia, Bhavin; Mahoney, Mary C.(2023-12-04)
Abstract: Creating a patient-centered experience is becoming increasingly important for radiology departments around the world. The goal of patient-centered radiology is to ensure that radiology services are sensitive to patients’ needs and desires. ...
Long-finned pilot whales (Globicephala melas) are the most frequently stranded cetaceans in the world; however, the predominant drivers of these events are poorly understood. In this study the levels of persistent organic pollutants from pilot whales ...
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium(2023-07-06)
In polygenic score (PGS) analysis, the coefficient of determination (R2) is a key statistic to evaluate efficacy. R2 is the proportion of phenotypic variance explained by the PGS, calculated in a cohort that is independent of the genome-wide association ...
Gustavsson, Simon T.; Enz, Tim J.; Tribble, James R.; Nilsson, Mattias; Lindqvist, Anna; Lindén, Christina; Hagström, Anna; Rutigliani, Carola; Lardner, Emma; Stålhammar, Gustav; Williams, Pete A.; Jóhannesson, Gauti(2023-11-01)
PURPOSE: To investigate whether nicotinamide (NAM) modulates retinal vasculature in glaucoma. METHODS: This was a prospective controlled clinical trial investigating animal and human histopathology. Participants included normotensive and ocular ...
Background: The prevalence of type 2 diabetes is increasing rapidly, particularly among younger age groups. Estimates suggest that people with diabetes die, on average, 6 years earlier than people without diabetes. We aimed to provide reliable estimates ...
International Headache Genetics Consortium(2023-06-12)
Epidemiological studies demonstrate an association between migraine and chronic kidney disease (CKD), while the genetic basis underlying the phenotypic association has not been investigated. We aimed to help avoid unnecessary interventions in individuals ...
Barkander, Anna; Economou, Mario A.; Jóhannesson, Gauti(2023-05-12)
PURPOSE: To evaluate the 2-year efficacy and safety of Kahook dual-blade (KDB) goniotomy in patients with medically uncontrolled glaucoma. METHODS: This was a retrospective case-series study of 90 consecutive patients with primary open-angle glaucoma ...
Objectives: To develop an intuitive and generally applicable system for the reporting, assessment, and documentation of ADC to complement standard BI-RADS criteria. Methods: This was a multicentric, retrospective analysis of 11 independently conducted ...
It has been demonstrated previously that a variety of carbonic anhydrase inhibitors (CAIs) can induce vasodilation in pre-contracted retinal arteriolar segments although with different efficacy and potency. Since the CAIs tested so far are able to ...
OBJECTIVES: This study aims to examine whether comorbidities affect the likelihood of reaching primary remission on methotrexate monotherapy as the first disease-modifying antirheumatic drug (DMARD) in early rheumatoid arthritis (RA). METHODS: We used ...
Azuara-Blanco, Augusto; McCorry, Noleen; Tatham, Andrew J.; Georgoulas, Stelios; Founti, Panayiota; Schweitzer, Cedric; Meier-Gibbons, Frances; Denis, Philippe; Tuulonen, Anja; Johannesson, Gauti; De La Casa, José María Martínez; Prokosch, Verena; Giannoulis, Dimitrios A.; Abegão Pinto, Luis; Garway-Heath, David; Topouzis, Fotis(2023-11-03)
Background/Aims: The goal of health research is to improve patients care and outcomes. Thus, it is essential that research addresses questions that are important to patients and clinicians. The aim of this study was to develop a list of priorities for ...
Jonmundsson, Thorarinn; Steindorsdottir, Anna E.; Austin, Thomas R.; Frick, Elisabet A.; Axelsson, Gisli T.; Launer, Lenore; Psaty, Bruce M.; Loureiro, Joseph; Orth, Anthony P.; Aspelund, Thor; Emilsson, Valur; Floyd, James S.; Jennings, Lori; Gudnason, Vilmundur; Gudmundsdottir, Valborg(2023-11-02)
AIMS: Atrial fibrillation (AF) is associated with high risk of comorbidities and mortality. Our aim was to examine causal and predictive relationships between 4137 serum proteins and incident AF in the prospective population-based Age, Gene/Environment ...
Lorenzetti, Alan P.R.; Kusebauch, Ulrike; Zaramela, Lívia S.; Wu, Wei Ju; de Almeida, João P.P.; Turkarslan, Serdar; de Lomana, Adrián L.G.; Gomes-Filho, José V.; Vêncio, Ricardo Z.N.; Moritz, Robert L.; Koide, Tie; Baliga, Nitin S.(2023-04-27)
The scale of post-transcriptional regulation and the implications of its interplay with other forms of regulation in environmental acclimation are underexplored for organisms of the domain Archaea. Here, we have investigated the scale of post-transcriptional ...
van Gennip, April C.E.; Satizabal, Claudia L.; Tracy, Russell P.; Sigurdsson, Sigurdur; Gudnason, Vilmundur; Launer, Lenore J.; van Sloten, Thomas T.(2023-08-02)
We investigated the associations of plasma neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and total tau (t-tau) with markers of cerebral small vessel disease (SVD) and with incident dementia. We also investigated whether associations ...
In plant science, it is an established method to obtain structural parameters of crops using image analysis. In recent years, deep learning techniques have improved the underlying processes significantly. However, since data acquisition is time and ...
The asymmetric synthesis of polyunsaturated triene C18:3 n-3 and C18:3 n-6 methoxylated ether lipids (MEL) of the 1-O-alkyl-sn-glycerol type is described as possible structural candidates for a triene C18:3 MEL of an unknown identity found in a mixture ...
Jack, Tullia; Bååth, Jonas; Heinonen, Jukka Taneli; Gram-Hanssen, Kirsten(2024)
In the original publication of the article, under the section “Conclusion”, the citation information was incorrectly given as “see also Bååth, 2022a” but it should have been “see also Bååth, 2018; 2022b”. The original article was updated.