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Browsing IRIS by Title

Browsing IRIS by Title

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  • Egnell, Christina; Heyman, Mats; Jónsson, Ólafur Gísli; Raja, Raheel A; Niinimäki, Riitta; Albertsen, Birgitte Klug; Schmiegelow, Kjeld; Stabell, Niklas; Vaitkeviciene, Goda; Lepik, Kristi; Harila-Saari, Arja; Ranta, Susanna (2022-03)
    Obesity is associated with poor outcomes in childhood acute lymphoblastic leukaemia (ALL). We explored whether severe treatment-related toxicity and treatment delays could explain this observation. This study included 1 443 children aged 2·0-17·9 years ...
  • Pak, Victoria M; Maislin, David G; Keenan, Brendan T.; Guo, Xiaofeng; Townsend, Ray; Benediktsdóttir, Bryndís; Pack, Allan I.; Gíslason, Þórarinn; Kuna, Samuel T. (2023-03)
    This study found no evidence that obesity significantly modifies the effect of 4 months of CPAP treatment on HOMA-IR. Longer duration of CPAP treatment may be needed in order to reduce insulin resistance and determine whether obesity modifies the effect. ...
  • Keenan, Brendan T; Magalang, Ulysses J; Mazzotti, Diego R; McArdle, Nigel; Gíslason, Þórarinn; Singh, Bhajan; Maislin, Greg; Pack, Allan I (2021-12-13)
  • Nikkilä, Rayan; Mäkitie, Antti; Carpén, Timo; Hansen, Johnni; Heikkinen, Sanna; Lynge, Elsebeth; Selander, Jenny; Mehlum, Ingrid Sivesind; Torfadottir, Jóhanna Eyrún; Salo, Tuula; Pukkala, Eero (2024-01)
    Purpose: Evaluate the occupational variation in incidence of oropharyngeal cancer (OPC). Methods: We calculated standardized incidence ratios (SIRs) of OPC in occupational categories in the Nordic countries relative to the entire national populations. ...
  • Kalkhoran, Siavash Beikoghli; Kararigas, Georgios (2022-02-01)
    Biological sex influences disease development and progression. The steroid hormone 17β-oestradiol (E2), along with its receptors, is expected to play a major role in the manifestation of sex differences. E2 exerts pleiotropic effects in a system-specific ...
  • Snorrason, Jón; Sigurðsson, Jón Friðrik (2022)
    Tilgangur: Ákveðið hlutfall starfsfólks á geðdeildum verður fyrir ofbeldi við störf sín. Fyrir flesta sem verða fyrir ofbeldi hefur það einhver áhrif. Þessi rannsókn sýnir umfang þessa vandamáls í geðþjónustu Landspítala. Aðferð: Rafrænn spurningalisti ...
  • Björnsson, Aron Hjalti; Harðarson, Þorgeir Orri; Ólafsson, Ingvar Hákon; Ragnarsson, Óskar; Sigurjónsdóttir, Helga Ágústa (2020-10)
    Kona á fertugsaldri leitaði á bráðamóttöku með tveggja vikna sögu um versnandi höfuðverk og tvísýni. Hún hafði í um 8 ár leitað til lækna vegna þyngdaraukningar, sykursýki og háþrýstings og fengið ráðleggingar um heilbrigðan lífsstíl sem bar ekki ...
  • Benediktsson, Rafn (2021-03)
  • Halldórsson, Þórhallur Ingi; Birgisdóttir, Bryndís Eva; Brantsæter, Anne Lise; Meltzer, Helle Margrete; Haugen, Margaretha; Þórsdóttir, Inga; Ólafsdóttir, Anna Sigríður; Olsen, Sjurdur F. (2021-01-29)
    BACKGROUND: A previous randomized dietary intervention in pregnant women from the 1970s, the Harlem Trial, reported retarded fetal growth and excesses of very early preterm births and neonatal deaths among those receiving high-protein supplementation. ...
  • Spitzer, Sonia Olivia; Sitnikov, Sergey; Kamen, Yasmine; Evans, Kimberley Anne; Kronenberg-Versteeg, Deborah; Dietmann, Sabine; de Faria, Omar; Agathou, Sylvia; Káradóttir, Ragnhildur Thóra (2019-02-06)
    Spitzer et al. show that oligodendrocyte progenitor cells (OPCs) acquire ion channels and sensitivity to neuronal activity that differ between region and age. The onset and decline of ion channels follow developmental milestones. This heterogeneity ...
  • Gunnarsson, Björn; Skogvoll, Eirik; Røislien, Jo; Smárason, Alexander Kristinn; Jónsdóttir, Ingibjörg Hanna (2017-06-12)
    Background Labor that progresses faster than anticipated may lead to unplanned out-of-hospital births. With the aim to improve planning of transportation to birthing institutions, this study investigated predictors of time to completion for the first ...
  • van Keulen, Danielle; Pouwer, Marianne G.; Emilsson, Valur; Matic, Ljubica Perisic; Pieterman, Elsbet J.; Hedin, Ulf; Gudnason, Vilmundur; Jennings, Lori L.; Holmstrøm, Kim; Nielsen, Boye Schnack; Pasterkamp, Gerard; Lindeman, Jan H.N.; van Gool, Alain J.; Sollewijn Gelpke, Maarten D.; Princen, Hans M.G.; Tempel, Dennie (2019-08-01)
    Objective Previous studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and ...
  • EFSA Scientific Committee (2021-10-01)
    This Opinion assesses the biological relevance of the non-monotonic dose responses (NMDR) identified in a previous EFSA External Report (Beausoleil et al., 2016) produced under GP/EFSA/SCER/2014/01 and the follow-up probabilistic assessment (Chevillotte ...
  • Friesgaard, Kristian Dahl; Vist, Gunn Elisabeth; Hyldmo, Per Kristian; Raatiniemi, Lasse; Kurola, Jouni; Larsen, Robert; Kongstad, Poul; Magnússon, Viðar; Sandberg, Mårten; Rehn, Marius; Rognås, Leif (2022-01-18)
    Introduction: Acute pain is a frequent symptom among patients in the pre-hospital setting, and opioids are the most widely used class of drugs for the relief of pain in these patients. However, the evidence base for opioid use in this setting appears ...
  • Harðardóttir, Hrönn; Aspelund, Thor; Zhu, Jianwei; Fall, Katja; Hauksdóttir, Arna; Fang, Fang; Lu, Donghao; Janson, Christer; Jónsson, Steinn; Valdimarsdóttir, Heiðdís; Valdimarsdóttir, Unnur Anna; Hardardottir, Hronn (2022-01)
    Purpose: The aim of this study was to assess the role of the patient’s background and perceived healthcare-related factors in symptoms of acute stress after lung cancer diagnosis. Methods: The study population consisted of 89 individuals referred for ...
  • Thorsteinsdottir, Unnur A; Runólfsdóttir, Hrafnhildur L.; Eiríksson, Finnur Freyr; Ágústsd., Inger María Schweitz; Eðvarðsson, Viðar Örn; Pálsson, Runólfur; Þorsteinsdóttir, Margrét (2024-03-01)
    Adenine phosphoribosyltransferase (APRT) deficiency is a rare , hereditary disorder characterized by renal excretion of 2,8-dihydroxyadenine (DHA), leading to kidney stone formation and chronic kidney disease (CKD). Treatment with a xanthine oxidoreductase ...
  • EuGMS SIG Pharmacology (2023-12)
    Inappropriate polypharmacy is highly prevalent among older adults and presents a significant healthcare concern. Conducting medication reviews and implementing deprescribing strategies in multimorbid older adults with polypharmacy are an inherently ...
  • Aloui, Salma; Qureshi, Pir Abdul Ahad Aziz; Bollineni, Vikram Rao (2024-02)
    Orbital plasmacytomas are exceedingly rare neoplasms characterized by the proliferation of monoclonal plasma cells in the orbital soft tissues. Their presentation and clinical course can be diverse, making early diagnosis and management challenging. ...
  • Karlsson, Vífill (2013-08-05)
    Ýmsir hafa haft áhyggjur af stöðugum straumi fólks frá landsbyggð til höfuðborgar. Ýmislegt hefur verið gert á vegum opinberra aðila til að draga úr straumnum, en með litlum árangri. Vísbendingar eru um að búferlaflutningar hafi breyst á Vesturlandi, ...