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Fletta eftir efnisorði "Ónæmisfræði"
Atriði 1-20 af 34
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(2023-01-20)Immaturity of the neonatal immune system contributes to increased susceptibility to infectious diseases and poor vaccine responses. Therefore, better strategies for early life vaccination are needed. Adjuvants can enhance the magnitude and duration of ... -
(Frontiers Media SA, 2019-09-26)Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited due to poorly developed follicular dendritic cells (FDC), causing generation of few antibody-secreting cells (ASCs) with ...
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(2023-11-13)Identifying mouth breathing during sleep in a reliable, non-invasive way is challenging and currently not included in sleep studies. However, it has a high clinical relevance in pediatrics, as it can negatively impact the physical and mental health of ...
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(2023-04)Ágrip Áratugum saman hafa ýmsir möguleikar verið nýttir til að bæta líðan, starfsemi og útlit manna með íhlutum, ígræddum með skurðaðgerðum. Silíkonpúðar hafa verið notaðir frá miðri síðustu öld til enduruppbyggingar á brjóstum, til dæmis eftir ...
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(MDPI AG, 2020-10-24)Malignant lymphomas are a heterogeneous group of malignancies that develop both in nodal and extranodal sites. The different tissues involved and the highly variable clinicopathological characteristics are linked to the association between the lymphoid ...
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(American Society for Microbiology, 2017-12-04)The airway epithelium restricts the penetration of inhaled pathogens into the underlying tissue and plays a crucial role in the innate immune defense against respiratory infections. The whooping cough agent, Bordetella pertussis, adheres to ciliated ...
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(Springer Nature, 2017-05-23)The major histocompatibility complex (MHC) encodes proteins that are central for antigen presentation and pathogen elimination. MHC class I (MHC-I) genes have attracted a great deal of interest among researchers in ecology and evolution and have been ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-06-03)Sértækur IgA skortur (sIgAD) er algengasti galli í sértæka ónæmiskerfinu. Gallinn er skilgreindur sem algjör skortur á IgA með eðlilegum IgG og IgM styrk í sermi. Tíðni sjúkdóma sem tengjast óeðlilegu ónæmissvari er hærri hjá sIgAD ...
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(PeerJ, 2015-12-07)Mechanical ventilation (MV) of patients can cause damage to bronchoalveolar epithelium, leading to a sterile inflammatory response, infection and in severe cases sepsis. Limited knowledge is available on the effects of MV on the innate immune defense ...
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(2023-04-14)INTRODUCTION: Visual sleep scoring has several shortcomings, including inter-scorer inconsistency, which may adversely affect diagnostic decision-making. Although automatic sleep staging in adults has been extensively studied, it is uncertain whether ...
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(University of Iceland, School of Engineering and Natural Sciences, Faculty of Life and Environmental Sciences, 2021-02)Innate immunity of the lung epithelium provides efficient defenses against pathogens or other stress factors by secretion of antimicrobial peptides, presence of cellular junction proteins and autophagy. Upon activation through epithelial cell receptors ...
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(University of Iceland, School of Health Sciences, Faculty of Medcine, 2016-10-14)Streptococcus pneumoniae, pneumókokkar, sem ekki voru næmir fyrir penisillíni (PÓP) fundust fyrst á Íslandi 1988 og urðu á fjórum árum 20% allra pneumókokka stofna sem greindust hjá sjúklingum. Flestir voru þeir af hjúpgerð 6Bii/E, CC90. Árið 2011 ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-03)Íslenski hesturinn er eini hestastofninn á Íslandi. Hestar voru fluttir hingað við landnám og hafa verið hreinræktaðir síðan. Vegna landfræðilegrar einangrunar er stofninn berskjaldaður fyrir mörgum sjúkdómsvöldum sem herja á hesta í öðrum löndum. ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2017-09-15)Mesenchymal stromal cells (MSC) are promising candidates for cellular therapy due to their ability to regenerate bone and cartilage and modulate immune responses. The use of MSC in cellular therapy is problematic due to the need for fetal bovine serum ...
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(2021-06-10)Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aHUS ...
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(2020-05-06)Rúmlega fimmtugur karlmaður sem hafði verið á ferðalagi erlendis veiktist við komuna til landsins með flensulíkum einkennum og greindist með COVID-19. Nokkrum dögum síðar versnandi honum af öndunarfæraeinkennum og lagðist inn á Landspítala. Hann reyndist ...
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(2021-01-30)Interleukin 6 (IL-6) is a multifunctional cytokine with both pro-A nd anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex disease ...
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(Springer Science and Business Media LLC, 2019-03-08)Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining representative data on AMR for healthy human populations is difficult. Here, we use metagenomic analysis of untreated sewage to characterize the bacterial resistome ...
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(Springer Science and Business Media LLC, 2018-10-25)Mutations in genes encoding subunits of the phagocyte NADPH oxidase complex are recognized to cause chronic granulomatous disease (CGD), a severe primary immunodeficiency. Here we describe how deficiency of CYBC1, a previously uncharacterized protein ...
Atriði 1-20 af 34