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Fletta eftir efnisorði "TFEB"

Fletta eftir efnisorði "TFEB"

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    MITF and TFEB cross-regulation in melanoma cells 
    Ballesteros Alvarez, Josue; Dilshat, Ramile; Fock, Valerie; Möller, Katrin; Karl, Ludwig; LARUE, Lionel; Ogmundsdottir, Margret H; Steingrimsson, Eirikur (Public Library of Science (PLoS), 2020-09-03)
    The MITF, TFEB, TFE3 and TFEC (MiT-TFE) proteins belong to the basic helix-loop-helix family of leucine zipper transcription factors. MITF is crucial for melanocyte development and differentiation, and has been termed a lineage-specific oncogene in ...
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    Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1 
    Zhang, T.; Zhou, Q.; Ogmundsdottir, Margret H; Möller, Katrin; Siddaway, R.; Larue, L.; Hsing, M.; Kong, S. W.; Goding, C. R.; Palsson, Arnar; Steingrimsson, Eirikur; Pignoni, F. (The Company of Biologists, 2015-06-19)
    The v-ATPase is a fundamental eukaryotic enzyme that is central to cellular homeostasis. Although its impact on key metabolic regulators such as TORC1 is well documented, our knowledge of mechanisms that regulate v-ATPase activity is limited. Here, we ...
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    A network of bHLHZip transcription factors in melanoma: Interactions of MITF, TFEB and TFE3 
    Ballesteros Álvarez, Josué A (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-01-10)
    The MITF, TFEB, TFE3 and TFEC (MiT-TFE) proteins belong to a larger family of basic helix-loop-helix leucine zipper transcription factors that are able to bind DNA and regulate gene expression. MITF is crucial for melanocyte development and has been ...
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    The role of MITF in regulating transcriptional cell states in melanoma 
    Remina, Dilixiati (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-03)
    The pigment producing melanocytes are derived from the neural crest cells and form precursor cells called melanoblasts. These cells proliferate and migrate to their destination in skin, hair and other organs where they differentiate into melanocytes ...