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Fletta eftir efnisorði "Slitgigt"

Fletta eftir efnisorði "Slitgigt"

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  • Jonsson, Helgi (Springer Nature, 2017-12)
    Background: Hand photography has been used in a number of studies to determine the presence and severity of hand osteoarthritis (HOA). The aim of this study was to present age and gender specific prevalences of HOA diagnosed by this method. Methods: ...
  • Styrkarsdottir, Unnur; Lund, S.H.; Saevarsdottir, S.; Magnusson, M.I.; Gunnarsdottir, K.; Norddahl, Gudmundur L.; Frigge, Michael L.; Ivarsdottir, E.V.; Bjornsdottir, Gyda; Holm, Hilma; Thorgeirsson, Guðmundur; Rafnar, T.; Jonsdottir, I.; Ingvarsson, T.; Jonsson, H.; Sulem, P.; Thorsteinsdottir, U.; Gudbjartsson, Daniel Fannar; Stefansson, K.; Thorgeirsson, Gudmundur; Ingvarsson, Þorvaldur (2021-11)
    Objective: Biomarkers for diagnosis and progression of osteoarthritis (OA) are lacking. This study was undertaken to identify circulating biomarkers for OA that could predict disease occurrence and/or progression to joint replacement. Methods: Using ...
  • arcOGEN consortium; HUNT All-In Pain; ARGO Consortium; Regeneron Genetics Center; Babis, George C; Cheung, Jason Pui Yin; Kang, Jae Hee; Kraft, Peter; Lietman, Steven A; Samartzis, Dino; Slagboom, P Eline; Stefansson, Kari; Thorsteinsdottir, Unnur; Tobias, Jonathan H; Uitterlinden, André G; Winsvold, Bendik; Zwart, John-Anker; Davey Smith, George; Sham, Pak Chung; Thorleifsson, Gudmar; Gaunt, Tom R; Morris, Andrew P; Valdes, Ana M; Tsezou, Aspasia; Cheah, Kathryn S E; Ikegawa, Shiro; Hveem, Kristian; Esko, Tõnu; Wilkinson, J Mark; Meulenbelt, Ingrid; Lee, Ming Ta Michael; van Meurs, Joyce B J; Styrkársdóttir, Unnur; Zeggini, Eleftheria (2021-09-01)
    Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated risk variants across 11 ...
  • Haugen, Ida K.; Felson, David; Abhishek, Abhishek; Berenbaum, Francis; Edwards, John James; Herrero Beaumont, Gabriel; Hermann-Eriksen, Merete; Hill, Catherine L.; Ishimori, Mariko; Jónsson, Helgi; Karjalainen, Teemu; Leung, Ying Ying; Maheu, Emmanuel; Mallen, Christian D.; Moe, Rikke Helene; Ramonda, Roberta; Ritschl, Valentin; Stamm, Tanja A.; Szekanecz, Zoltan; van der Giesen, Florus J.; Ritt, Marco J.P.F.; Wittoek, Ruth; Kjeken, Ingvild; Osteras, Nina; van de Stadt, Lotte A.; Englund, Martin; Dziedzic, Krysia S.; Marshall, M.; Bierma-Zeinstra, Sita; Hansen, Paul; Greibrokk, Elsie; Smeets, Wilma; Kloppenburg, Margreet (2022-02-04)
    ObjectivesIn Phase 1 of developing new hand osteoarthritis (OA) classification criteria, features associated with hand OA were identified in a population with hand complaints. Radiographic findings could better discriminate patients with hand OA and ...
  • HUNT All-In Pain; ARGO Consortium; Regeneron Genetics Center; arcOGEN consortium (2021-11-24)
    (Cell 184, 4784–4818.e1–e16, September 2, 2021) In this article, we carried out a multi-cohort GWAS meta-analysis for 11 osteoarthritis phenotypes. Since publication, we have become aware of the following typographical errors that were introduced during ...
  • Styrkarsdottir, Unnur; Stefansson, Olafur A.; Gunnarsdottir, Kristbjorg; Thorleifsson, Gudmar; Lund, Sigrún Helga; Stefansdottir, Lilja; Juliusson, Kristinn; Ágústsdóttir, Arna B.; Zink, Florian; Halldorsson, Gisli; Ivarsdottir, Erna V.; Benonisdottir, Stefania; Jonsson, Hakon; Gylfason, Arnaldur; Norland, Kristjan; Trajanoska, Katerina; Boer, Cindy G.; Southam, Lorraine; Leung, Jason C. S.; Tang, Nelson L. S.; Kwok, Timothy C. Y.; Lee, Jenny S. W.; Ho, Suzanne C.; Byrjalsen, Inger; Center, Jacqueline R.; Lee, Seung Hun; Koh, Jung-Min; Lohmander, L. Stefan; Ho-Pham, Lan T.; Nguyen, Tuan V.; Eisman, John A.; Woo, Jean; Leung, Ping-C.; Loughlin, John; Zeggini, Eleftheria; Christiansen, Claus; Rivadeneira, Fernando; van Meurs, Joyce; Uitterlinden, Andre G.; Mogensen, Brynjólfur; Jonsson, Helgi; Ingvarsson, Þorvaldur; Sigurdsson, Gunnar; Benediktsson, Rafn; sulem, patrick; Jonsdottir, Ingileif; Másson, Gísli; Holm, Hilma; Norddahl, Gudmundur L.; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Stefansson, Kari (Springer Science and Business Media LLC, 2019-05-03)
    Bone area is one measure of bone size that is easily derived from dual-energy X-ray absorptiometry (DXA) scans. In a GWA study of DXA bone area of the hip and lumbar spine (N ≥ 28,954), we find thirteen independent association signals at twelve loci ...
  • Marshall, Michelle; Jonsson, Helgi; Helgadottir, Gudrun P.; Nicholls, Elaine; Myers, Helen; Jansen, Victoria; van der Windt, Danielle (Springer Science and Business Media LLC, 2019-10-27)
    Background: To determine the longitudinal construct validity of assessing hand OA progression on digital photographs over 7 years compared with progression determined from radiographs, clinical features and change in symptoms. Methods: Participants ...
  • Gudbjornsson, Bjorn; Geirsson, Árni J.; Krogh, Niels Steen (Dove Medical Press Ltd., 2018-05)
    Objective: To explore differences in response to a low dosage regimen of infliximab with an escalating dosage in comparison to a standard dosage of etanercept and adalimumab in patients with psoriatic arthritis (PsA). Methods: Biologically naïve PsA ...
  • Gestsdóttir, Hildur (University of Iceland, School of Humanities, Faculty of History and Philosophy, 2014)
    Osteoarthritis has been intensively studied within the field of palaeopathology. For decades there was assumed to be a direct link between activity and the development of osteoarthritis, and this was reflected in the work which was carried out, with ...
  • Turmezei, Thomas; Treece, Graham; Gee, A. H.; Sigurðsson, Sigurður; Jonsson, Helgi; Aspelund, Thor; Gudnason, Vilmundur; Poole, Kenneth E.S. (Springer Science and Business Media LLC, 2020-03-05)
    Osteoarthritis is an increasingly important health problem for which the main treatment remains joint replacement. Therapy developments have been hampered by a lack of biomarkers that can reliably predict disease, while 2D radiographs interpreted by ...
  • Hálfdanardóttir, Freyja; Ramsey, Dan K.; Briem, Kristin (Hindawi Limited, 2018)
    The purpose of this study was to examine the infuence of trunk lean and contralateral hip abductor strength on the peak knee adduction moment (KAM) and rate of loading in persons with moderate medial knee osteoarthritis. Tirty-one males (17 ...