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Browsing by Subject "Rheumatology"

Browsing by Subject "Rheumatology"

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    Abatacept in rheumatoid arthritis : Survival on drug, clinical outcomes, and their predictors - Data from a large national quality register 
    Cagnotto, Giovanni; Willim, Minna; Nilsson, Jan Åke; Compagno, Michele; Jacobsson, Lennart T.H.; Saevarsdottir, Saedis; Turesson, Carl (2020-01-22)
    Background: There are limited data regarding efficacy of abatacept treatment for rheumatoid arthritis (RA) outside clinical trials. Quality registers have been useful for observational studies on tumor necrosis factor inhibition in clinical practice. ...
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    Association of female sex and positive rheumatoid factor with low serum infliximab and anti-drug antibodies, related to treatment failure in early rheumatoid arthritis : results from the SWEFOT trial population 
    for the SWEFOT study group (2019-09-03)
    Objective: Infliximab-treated patients with rheumatoid arthritis (RA) may respond insufficiently due to low serum infliximab (sIFX) levels, caused by anti-drug antibodies (ADAs). However, monitoring of sIFX and ADAs is not routinely implemented, and ...
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    Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39 
    Spiliopoulou, Athina; Colombo, Marco; Plant, Darren; Nair, Nisha; Cui, Jing; Coenen, Marieke J.H.; Ikari, Katsunori; Yamanaka, Hisashi; Saevarsdottir, Saedis; Padyukov, Leonid; Bridges, S. Louis; Kimberly, Robert P.; Okada, Yukinori; Van Riel, Piet L.C.M.; Wolbink, Gertjan; Van Der Horst-Bruinsma, Irene E.; De Vries, Niek; Tak, Paul P.; Ohmura, Koichiro; Canhão, Helena; Guchelaar, Henk Jan; Huizinga, Tom W.J.; Criswell, Lindsey A.; Raychaudhuri, Soumya; Weinblatt, Michael E.; Wilson, Anthony G.; Mariette, Xavier; Isaacs, John D.; Morgan, Ann W.; Pitzalis, Costantino; Barton, Anne; Mckeigue, Paul (2019-08-01)
    Objectives We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid arthritis (RA) could be localised by considering known genetic susceptibility loci for relevant traits and to evaluate the usefulness of these ...
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    Correction to : Correction to: Do patient-reported measures of disease activity in rheumatoid arthritis vary between countries? Results from a Nordic collaboration (Rheumatology (Oxford, England) (2022) 61 11 (4286-4296)) 
    Delcoigne, Bénédicte; Provan, Sella Aarrestad; Hammer, Hilde Berner; Di Giuseppe, Daniela; Frisell, Thomas; Glintborg, Bente; Grondal, Gerdur; Gudbjornsson, Bjorn; Hetland, Merete Lund; Michelsen, Brigitte; Nordström, Dan; Relas, Heikki; Askling, Johan (2022-03-25)
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    Development of classification criteria for hand osteoarthritis : Comparative analyses of persons with and without hand osteoarthritis 
    Haugen, Ida K.; Felson, David T.; Abhishek, Abhishek; Berenbaum, Francis; Bierma-Zeinstra, Sita; Borgen, Tove; Herrero Beaumont, Gabriel; Ishimori, Mariko; Jonsson, Helgi; Kroon, Féline P.B.; Maheu, Emmanuel; Ramonda, Roberta; Ritschl, Valentin; Stamm, Tanja A.; Van Der Heijde, Desirée; Wittoek, Ruth; Greibrokk, Elsie; Smeets, Wilma; Kloppenburg, Margreet (2020-06-25)
    Objectives Further knowledge about typical hand osteoarthritis (OA) characteristics is needed for the development of new classification criteria for hand OA. Methods In a cross-sectional multi-centre international study, a convenience sample of patients ...
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    Development of radiographic classification criteria for hand osteoarthritis : a methodological report (Phase 2) 
    Haugen, Ida K.; Felson, David; Abhishek, Abhishek; Berenbaum, Francis; Edwards, John James; Herrero Beaumont, Gabriel; Hermann-Eriksen, Merete; Hill, Catherine L.; Ishimori, Mariko; Jonsson, Helgi; Karjalainen, Teemu; Leung, Ying Ying; Maheu, Emmanuel; Mallen, Christian D.; Moe, Rikke Helene; Ramonda, Roberta; Ritschl, Valentin; Stamm, Tanja A.; Szekanecz, Zoltan; van der Giesen, Florus J.; Ritt, Marco J.P.F.; Wittoek, Ruth; Kjeken, Ingvild; Osteras, Nina; van de Stadt, Lotte A.; Englund, Martin; Dziedzic, Krysia S.; Marshall, M.; Bierma-Zeinstra, Sita; Hansen, Paul; Greibrokk, Elsie; Smeets, Wilma; Kloppenburg, Margreet (2022-02-04)
    ObjectivesIn Phase 1 of developing new hand osteoarthritis (OA) classification criteria, features associated with hand OA were identified in a population with hand complaints. Radiographic findings could better discriminate patients with hand OA and ...
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    Does persistence to methotrexate treatment in early rheumatoid arthritis have a familial component? 
    Sysojev, Anton Öberg; Frisell, Thomas; Delcoigne, Bénédicte; Saevarsdottir, Saedis; Askling, Johan; Westerlind, Helga (2022-08-06)
    Objectives: To assess whether persistence to treatment with methotrexate (MTX) in early rheumatoid arthritis (RA) is shared among first-degree relatives with RA and to estimate any underlying heritability. Methods: First-degree relative pairs diagnosed ...
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    Effectiveness and treatment retention of TNF inhibitors when used as monotherapy versus comedication with csDMARDs in 15 332 patients with psoriatic arthritis. Data from the EuroSpA collaboration 
    Lindström, Ulf; Di Giuseppe, Daniela; Delcoigne, Bénédicte; Glintborg, Bente; Möller, Burkhard; Ciurea, Adrian; Pombo-Suarez, Manuel; Sanchez-Piedra, Carlos; Eklund, Kari; Relas, Heikki; Guðbjörnsson, Björn; Löve, Þorvarður Jón; Jones, Gareth T.; Codreanu, Catalin; Ionescu, Ruxandra; Nekvindova, Lucie; Závada, Jakub; Atas, Nuh; Yolbas, Servet; Fagerli, Karen Minde; Michelsen, Brigitte; Rotar, Ziga; Tomšič, Matija; Iannone, Florenzo; Santos, Maria Jose; Avila-Ribeiro, Pedro; Ørnbjerg, Lykke Midtbøll; Østergaard, Mikkel; Jacobsson, Lennart T.H.; Askling, Johan; Nissen, Michael J. (2021-06-03)
    Background Comedication with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) during treatment with tumour necrosis factor inhibitors (TNFi) is extensively used in psoriatic arthritis (PsA), although the additive benefit remains ...
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    Is tea consumption associated with reduction of risk of rheumatoid arthritis? A Swedish case-control study 
    Westerlind, Helga; Palmqvist, Ida; Saevarsdottir, Saedis; Alfredsson, Lars; Klareskog, Lars; Di Giuseppe, Daniela (2021-08-07)
    BACKGROUND: Tea is a popular beverage around the world and has properties that can affect the immune system. The association between tea consumption and the risk of rheumatoid arthritis (RA), a chronic autoimmune disease primarily affecting the joints, ...
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    Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset 
    Sævarsdóttir, Sædís; Stefansdottir, L.; Sulem, P.; Thorleifsson, G.; Ferkingstad, E.; Rutsdottir, G.; Glintborg, B.; Westerlind, H.; Gröndal, Gerður María; Loft, I.C.; Sorensen, S.B.; Lie, B.A.; Brink, M.; Arlestig, L.; Arnthorsson, A.O.; Baecklund, E.; Banasik, K.; Bank, S.; Bjorkman, L.I.; Ellingsen, T.; Erikstrup, C.; Frei, O.; Gjertsson, I.; Gudbjartsson, D.F.; Gudjonsson, S.A.; Halldorsson, G.H.; Hendricks, O.; Hillert, J.; Hogdall, E.; Jacobsen, Sø; Jensen, D.V.; Jonsson, H.; Kastbom, A.; Kockum, I.; Kristensen, S.; Kristjansdottir, H.; Larsen, M.H.; Linauskas, A.; Hauge, E.-M.; Loft, A.G.; Lúðvíksson, Björn Rúnar; Lund, S.H.; Markusson, T.; Masson, G.; Melsted, P.; Moore, K.H.S.; Munk, H.; Nielsen, K.R.; Norddahl, G.L.; Oddsson, A.; Olafsdottir, T.A.; Olason, P.I.; Olsson, T.; Ostrowski, S.R.; Hørslev-Petersen, K.; Rognvaldsson, S.; Sanner, H.; Silberberg, G.N.; Stefansson, H.; Sørensen, E.; Sørensen, I.J.; Turesson, C.; Bergman, T.; Alfredsson, L.; Kvien, T.K.; Brunak, Sø; Steinsson, K.; Andersen, V.; Andreassen, O.A.; Rantapää-Dahlqvist, S.; Hetland, M.L.; Klareskog, L.; Askling, J.; Padyukov, L.; Pedersen, O.B.V.; Thorsteinsdottir, U.; Jonsdottir, I.; Stefánsson, Kári; Saevarsdottir, S.; Markússon, Þorsteinn (2022-04-25)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...
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    Musculoskeletal pain and its effect on daily activity and behaviour in Icelandic children and youths with juvenile idiopathic arthritis : a cross-sectional case-control study 
    Óskarsdóttir, Svanhildur; Kristjansdottir, Audur; Guðmundsdóttir, Judith Amalía; Kamban, Sólrún W; Licina, Zinajda Alomerovic; Gudmundsdottir, Drifa Bjork; Guðjónsdóttir, Þjóðbjörg (2022-07-15)
    Background: Juvenile idiopathic arthritis is characterised by recurring episodes of acute inflammation, with joint swelling in one or more joints, often accompanied by pain. These episodes can now be controlled better than in the past because of a new ...
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    Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study 
    Hedenstierna, Louise; Hedström, Anna Karin; Klareskog, Lars; Di Giuseppe, Daniela; Alfredsson, Lars; Askling, Johan; Ernestam, Sofia; Saevarsdottir, Saedis; Ljung, Lotta (2022-08-23)
    Objectives: To investigate the association between psychosocial vulnerability, defined as either low social support or low decision latitude at work, and disease remission at 3, 12, and 60 months in patients with rheumatoid arthritis (RA). Methods: ...
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    Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis—a spin-off study of the NORD-STAR randomized clinical trial 
    Stockfelt, Marit; Lundell, Anna Carin; Hetland, Merete Lund; Østergaard, Mikkel; Uhlig, Till; Heiberg, Marte Schrumpf; Haavardsholm, Espen A.; Nurmohamed, Michael T.; Lampa, Jon; Nordström, Dan; Petersen, Kim Hørslev; Guðbjörnsson, Björn; Gröndal, Gerður; Aldridge, Jonathan; Andersson, Kerstin; Blennow, Kaj; Zetterberg, Henrik; van Vollenhoven, Ronald; Rudin, Anna (2021-07-13)
    Background: The type I interferon (IFN) gene signature is present in a subgroup of patients with early rheumatoid arthritis (RA). Protein levels of IFNα have not been measured in RA and it is unknown whether they associate with clinical characteristics ...
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    Predictors of ASDAS-CRP inactive disease in axial spondyloarthritis during treatment with TNF-inhibitors : Data from the EuroSpA collaboration 
    Ørnbjerg, Lykke Midtbøll; Linde, Louise; Georgiadis, Stylianos; Horskjær Rasmussen, Simon; Lindström, Ulf; Askling, Johan; Michelsen, Brigitte; Di Giuseppe, Daniela; Wallman, Johan K.; Pavelka, Karel; Závada, Jakub; Nissen, Michael J; Jones, Gareth T.; Relas, Heikki; Pirilä, Laura; Tomšič, Matija; Rotar, Ziga; Geirsson, Árni Jón; Guðbjörnsson, Björn; Kristianslund, Eirik K.; van sder Horst-Bruinsma, Irene; Loft, Anne Gitte; Laas, Karin; Iannone, Florenzo; Corrado, Addolorata; Ciurea, Adrian; Santos, Maria José; Santos, Helena; Codreanu, Catalin; Akkoc, Nurullah; Gunduz, Ozgul S.; Glintborg, Bente; Østergaard, Mikkel; Lund Hetland, Merete (2022-10-01)
    Objectives: In patients with axial spondyloarthritis (axSpA) initiating their first tumor necrosis factor alpha-inhibitor (TNFi), we aimed to identify common baseline predictors of Ankylosing Spondylitis Disease Activity Score (ASDAS-CRP) inactive ...
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    Real-World Six- and Twelve-Month Drug Retention, Remission, and Response Rates of Secukinumab in 2,017 Patients With Psoriatic Arthritis in Thirteen European Countries 
    Michelsen, Brigitte; Georgiadis, Stylianos; Di Giuseppe, Daniela; Loft, Anne G.; Nissen, Michael J.; Iannone, Florenzo; Pombo-Suarez, Manuel; Mann, Herman; Rotar, Ziga; Eklund, Kari K.; Kvien, Tore K.; Santos, Maria J.; Guðbjörnsson, Björn; Codreanu, Catalin; Yilmaz, Sema; Wallman, Johan K.; Brahe, Cecilie H.; Möller, Burkhard; Favalli, Ennio G.; Sánchez-Piedra, Carlos; Nekvindova, Lucie; Tomsic, Matija; Trokovic, Nina; Kristianslund, Eirik K.; Santos, Helena; Löve, Þorvarður Jón; Ionescu, Ruxandra; Pehlivan, Yavuz; Jones, Gareth T.; van der Horst-Bruinsma, Irene; Ørnbjerg, Lykke M.; Østergaard, Mikkel; Hetland, Merete L. (2022-04-29)
    Objective: There is a lack of real-life studies on interleukin-17 (IL-17) inhibition in psoriatic arthritis (PsA). We assessed real-life 6- and 12-month effectiveness (i.e., retention, remission, low disease activity [LDA], and response rates) of the ...
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    Retinal toxicity in a multinational inception cohort of patients with systemic lupus on hydroxychloroquine 
    Almeida-Brasil, Celline C; Hanly, John G; Urowitz, Murray; Clarke, Ann Elaine; Ruiz-Irastorza, Guillermo; Gordon, Caroline; Ramsey-Goldman, Rosalind; Petri, Michelle; Ginzler, Ellen M; Wallace, Daniel J; Bae, Sang-Cheol; Romero-Diaz, Juanita; Dooley, Mary Anne; Peschken, Christine; Isenberg, David; Rahman, Anisur; Manzi, Susan; Jacobsen, Søren; Sam Lim, Sung; Van vollenhoven, Ronald F.; Nived, Ola; Jönsen, Andreas; Kamen, Diane L; Aranow, Cynthia; Sánchez-Guerrero, Jorge; Gladman, Dafna D.; Fortin, Paul R; Alarcon, Graciela S.; Merrill, Joan T; Kalunian, Kenneth; Ramos-Casals, Manuel; Steinsson, Kristján; Zoma, A A; Askanase, Anca D; Khamashta, Munther; Bruce, Ian N.; Inanc, Murat; Lukusa, Luck; Bernatsky, Sasha (2022-11-01)
    Objective To evaluate hydroxychloroquine (HCQ)-related retinal toxicity in the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort. Methods Data were collected at annual study visits between 1999 and 2019. We followed patients ...
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    Risk Factors for Diagnosis of Psoriatic Arthritis, Psoriasis, Rheumatoid Arthritis, and Ankylosing Spondylitis : A Set of Parallel Case-control Studies 
    Meer, Elana; Thrastardottir, Telma; Wang, Xingmei; Dubreuil, Maureen; Chen, Yong; Gelfand, Joel M.; Love, Thorvardur J.; Ogdie, Alexis (2022-01-01)
    Objective. To compare potential risk factors for the diagnosis of psoriatic arthritis (PsA), psoriasis (PsO), rheumatoid arthritis (RA), and ankylosing spondylitis (AS). Methods. Four parallel case-control studies were conducted within The Health ...
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    Short-term, intermediate-term and long-term risks of acute coronary syndrome in cohorts of patients with RA starting biologic DMARDs : results from four Nordic countries 
    Delcoigne, Benedicte; Ljung, Lotta; Provan, Sella A; Glintborg, Bente; Hetland, Merete Lund; Grøn, Kathrine Lederballe; Peltomaa, Ritva; Relas, Heikki; Turesson, Carl; Guðbjörnsson, Björn; Michelsen, Brigitte; Askling, Johan (2022-03-22)
    OBJECTIVES: To compare the 1-year, 2-year and 5-year incidences of acute coronary syndrome (ACS) in patients with rheumatoid arthritis (RA) starting any of the biologic disease-modifying antirheumatic drugs (bDMARDs) currently available in clinical ...
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    Sleep problems in rheumatoid arthritis over 12 years from diagnosis : Results from the Swedish EIRA study 
    Lyne, Lauren; Åkerstedt, Torbjörn; Alfredsson, Lars; Lehtonen, Tiina; Sævarsdóttir, Sædís; Klareskog, Lars; Westerlind, Helga (2022-01-05)
    Objective Most studies of rheumatoid arthritis (RA) and sleep have focused on established RA. We here investigate sleep quality and sleep duration in patients with newly diagnosed RA and during 1-12 years after diagnosis. Methods Data were collected ...
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    Social stressors and risk of rheumatoid arthritis and their relationship to known modifiable risk factors : results from the Swedish EIRA study 
    Hedenstierna, L.; Opava, C. H.; Askling, J.; Jiang, X.; Ernestam, S.; Alfredsson, L.; Klareskog, L.; Sævarsdóttir, Sædís (2021-01-12)
    Objectives: To investigate whether low social support or low decision latitude at work correlate with risk of rheumatoid arthritis (RA), and whether and how those factors are associated with known modifiable risk factors for RA. Method: The Swedish ...