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Fletta eftir efnisorði "Polygenic risk score"

Fletta eftir efnisorði "Polygenic risk score"

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    Assessing thyroid cancer risk using polygenic risk scores 
    Liyanarachchi, Sandya; Gudmundsson, Julius; Ferkingstad, Egil; He, Huiling; Jónasson, Jón Gunnlaugur; Tragante, Vinicius; Asselbergs, Folkert W.; Xu, Li; Kiemeney, Lambertus A.; Netea-Maier, Romana T.; Mayordomo, Jose I.; Plantinga, Theo S.; Hjartarson, Hannes; Hrafnkelsson, Jón; Sturgis, Erich M.; Brock, Pamela; Nabhan, Fadi; Thorleifsson, Gudmar; Ringel, Matthew D.; Stefansson, Kari; de la Chapelle, Albert (2020-03-17)
    Genome-wide association studies (GWASs) have identified at least 10 single-nucleotide polymorphisms (SNPs) associated with papillary thyroid cancer (PTC) risk. Most of these SNPs are common variants with small to moderate effect sizes. Here we assessed ...
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    A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study) 
    Jonmundsson, Thorarinn; Steindorsdottir, Anna E.; Austin, Thomas R.; Frick, Elisabet A.; Axelsson, Gisli T.; Launer, Lenore; Psaty, Bruce M.; Loureiro, Joseph; Orth, Anthony P.; Aspelund, Thor; Emilsson, Valur; Floyd, James S.; Jennings, Lori; Gudnason, Vilmundur; Gudmundsdottir, Valborg (2023-11-02)
    AIMS: Atrial fibrillation (AF) is associated with high risk of comorbidities and mortality. Our aim was to examine causal and predictive relationships between 4137 serum proteins and incident AF in the prospective population-based Age, Gene/Environment ...