Opin vísindi

Fletta eftir efnisorði "Nucleic acid structure"

Fletta eftir efnisorði "Nucleic acid structure"

Röðun: Raða: Niðurstöður:

  • Icon
    Noncovalent and site-directed spin labeling of duplex RNA 
    Kamble, Nilesh Ramesh; Gränz, Markus; Prisner, Thomas F.; Sigurdsson, Snorri (Royal Society of Chemistry (RSC), 2016)
    An isoindoline-nitroxide derivative of guanine (G, "G-spin") was shown to bind specifically and effectively to abasic sites in duplex RNAs. Distance measurements on a G-labeled duplex RNA with PELDOR (DEER) showed a strong orientation dependence. Thus, ...
  • Icon
    Site-directed spin labeling of 2′-amino groups in RNA with isoindoline nitroxides that are resistant to reduction 
    Saha, Subham; Jagtap, Anil P.; Sigurdsson, Snorri (Royal Society of Chemistry (RSC), 2015)
    Two aromatic isothiocyanates, derived from isoindoline nitroxides, were synthesized and selectively reacted with 2′-amino groups in RNA. The spin labels displayed limited mobility in RNA, making them promising candidates for distance measurements by ...