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Browsing by Subject "Náttúrufræðingar"

Browsing by Subject "Náttúrufræðingar"

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  • Rögnvaldsson, Kristján G; Bjarnason, Agnar; Kristinsson, Karl Gústaf; Bragason, Hörður T; Erlendsdóttir, Helga; Þorgeirsson, Guðmundur; Gottfreðsson, Magnús (2022-08)
    BACKGROUND: Pneumonia is commonly caused by Streptococcus pneumoniae (pneumococcus) and associated with subsequent cardiovascular complications and increased mortality. Potential short-term survival benefits conferred by acetylsalicylic acid (ASA) use ...
  • Hognason, Hakon Bjorn; Stefansdottir, Vigdis Fjola; Thorolfsdottir, Eirny Tholl; Jonsson, Jon Johannes; Bjornsson, Hans Tomas (2022-01-04)
    INNGANGUR Formleg erfðaráðgjafareining hefur verið starfrækt á Landspítala við Hringbraut frá árinu 2006. Samhliða hefur áhugi og þörf á erfðalæknisfræði í almennri heilbrigðisþjónustu aukist til muna. Í þessari grein er starfsemi og útkoma erfðarannsókna ...
  • Karlsson, Róbert Arnar; Ólafsdottir, Ólöf Birna; Helgadóttir, Védis; Belhadj, Soumaya; Elíasdóttir, Þórunn Scheving; Stefánsson, Einar; Harðarson, Sveinn Hákon (2021-12)
    Purpose Retinal oximetry is a technique based on spectrophotometry where images are analyzed with software capable of calculating vessel oxygen saturation and vessel diameter. In this study, the effect of automation of measurements of retinal vessel ...
  • Harðardóttir, Ingibjörg; Anderson, Kimberley Jade; Ósvaldsdóttir, Árný Björg; Atzinger, Birgit; Traustadóttir, Gunnhildur Ásta; Jensen, Kirstine Nolling; Lárusdóttir, Aðalheiður Elín; Bergþórsson, Jón Þór; Magnúsdóttir, Erna (2020-07-09)
    Waldenström’s macroglobulinemia (WM) is a non-Hodgkin lymphoma, resulting in antibody-secreting lymphoplasmacytic cells in the bone marrow and pathologies resulting from high levels of monoclonal immunoglobulin M (IgM) in the blood. Despite the key ...
  • Ingþórsson, Sævar; Traustadóttir, Gunnhildur Ásta; Guðjónsson, Þórarinn (2022-10-24)
    The human breast gland is a unique organ as most of its development occurs postnatally between menarche and menopause, a period ranging from 30 to 40 years. During this period, the monthly menstruation cycle drives the mammary gland through phases of ...
  • Ingþórsson, Sævar; Hilmarsdóttir, Bylgja; Kricker, Jennifer; Magnússon, Magnús Karl; Guðjónsson, Þórarinn (2015)
    Myoepithelial cells (MEPs) are specialized cells derived from epithelial progenitor cells, yet they also express the contractile machinery of smooth muscle cells. MEPs are prominent in glandular tissues where their function is to help expel secretions ...
  • GEMO Study Collaborators; EMBRACE Collaborators; SWE-BRCA Investigators; kConFab Investigators; HEBON Investigators (2022-10-06)
    The contribution of germline copy number variants (CNVs) to risk of developing cancer in individuals with pathogenic BRCA1 or BRCA2 variants remains relatively unknown. We conducted the largest genome-wide analysis of CNVs in 15,342 BRCA1 and 10,740 ...
  • Sigurdardottir, Anna Karen; Jonasdottir, Arna Steinunn; Asbjarnarson, Arni; Helgudottir, Hildur Run; Gudjonsson, Thorarinn; Traustadottir, Gunnhildur Asta (2021-12)
    Due to an error during typesetting, an incomplete Supplementary file was originally published with this article. Supplementary figures were missing and this has now been uploaded. The original article has been corrected.
  • Jensen, Kirstine Nolling; Heijink, Marieke; Giera, Martin; Freysdóttir, Jóna; Harðardóttir, Ingibjörg (2022-01-01)
    Purpose: To determine the effects of dietary omega-3 polyunsaturated fatty acids (PUFAs) on recruitment of natural killer (NK) cells and resolution responses in antigen-induced peritonitis in mice. Methods: Mice were fed fish oil-enriched or control ...
  • Oskarsson, Gudjon R.; Magnusson, Magnus K.; Oddsson, Asmundur; Jensson, Brynjar O.; Fridriksdottir, Run; Arnadottir, Gudny A.; Katrinardottir, Hildigunnur; Rognvaldsson, Solvi; Halldorsson, Gisli H.; Sveinbjornsson, Gardar; Ivarsdottir, Erna V.; Stefansdottir, Lilja; Ferkingstad, Egil; Norland, Kristjan; Tragante, Vinicius; Saemundsdottir, Jona; Jonasdottir, Aslaug; Jonasdottir, Adalbjorg; Sigurjonsdottir, Svanhvit; Petursdottir, Karen O.; Davidsson, Olafur B.; Rafnar, Thorunn; Holm, Hilma; Olafsson, Isleifur; Onundarson, Pall T.; Vidarsson, Brynjar; Sigurdardottir, Olof; Masson, Gisli; Gudbjartsson, Daniel F.; Jonsdottir, Ingileif; Norddahl, Gudmundur L.; Thorsteinsdottir, Unnur; Sulem, Patrick; Stefansson, Kari (2022-06-01)
    The characteristic lobulated nuclear morphology of granulocytes is partially determined by composition of nuclear envelope proteins. Abnormal nuclear morphology is primarily observed as an increased number of hypolobulated immature neutrophils, called ...
  • Grinde, Maria T; Hilmarsdóttir, Bylgja; Tunset, Hanna Maja; Henriksen, Ida Marie; Kim, Jana; Haugen, Mads H; Rye, Morten Beck; Mælandsmo, Gunhild M; Moestue, Siver A (2019-05-14)
    INTRODUCTION: Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 has shown promising effects ...
  • Bæringsdóttir, Birta; Erlendsdóttir, Helga; Björnsdóttir, Erla Soffía; Martins, Elisabete R.; Ramirez, Mário; Haraldsson, Ásgeir; Þórkelsson, Þórður (2021-09-23)
    Introduction. Group B streptococcus (GBS) is a leading cause of invasive neonatal infections. These have been divided into early-onset disease (EOD; <7 days) and late-onset disease (LOD; 7–89 days), with different GBS clonal complexes (CCs) associated ...
  • Amirfallah, Arsalan; Knutsdottir, Hildur; Arason, Aðalgeir; Hilmarsdóttir, Bylgja; Jóhannsson, Óskar Þór; Agnarsson, Bjarni Agnar; Barkardottir, Rosa B.; Reynisdottir, Inga (2021-11-19)
    Breast cancer is the cancer most often diagnosed in women. MicroRNAs (MIRs) are short RNA molecules that bind mRNA resulting in their downregulation. MIR21 has been shown to be an oncomiR in most cancer types, including breast cancer. Most of the effects ...
  • The Global Pneumococcal Sequencing Consortium (2022-02-11)
    Background: Pneumococcal disease outbreaks of vaccine preventable serotype 4 sequence type (ST)801 in shipyards have been reported in several countries. We aimed to use genomics to establish any international links between them. Methods: Sequence data ...
  • Gunnarsdottir, Anna Kristin; Erlendsdottir, Helga; Gottfredsson, Magnus (2022-03-03)
    INNGANGUR Bakteríur af ættkvíslinni Bacillus finnast víða í umhverfinu og eru almennt taldar hafa litla meinvirkni, að miltisbrandsbakteríunni B. anthracis undanskilinni. Oft er álitið að um mengun sé að ræða ef Bacillus-tegundir finnast með ræktun. ...
  • DBDS Genomic Consortium (2022-10-24)
    Nonalcoholic fatty liver (NAFL) and its sequelae are growing health problems. We performed a genome-wide association study of NAFL, cirrhosis and hepatocellular carcinoma, and integrated the findings with expression and proteomic data. For NAFL, we ...
  • Sigurdardottir, Fjola D.; Øverby, Caroline Tonje; Nikkonen, Sami; Karhu, Tuomas; Dammen, Toril; Nordhus, Inger Hilde; Thorshov, Thea; Einvik, Gunnar; Kainulainen, Samu; Leppänen, Timo; Arnardóttir, Erna Sif; Töyräs, Juha; Omland, Torbjørn; Hrubos-Strøm, Harald (2022-03-15)
    Novel diagnostic markers for obstructive sleep apnea beyond the apnea–hypopnea index (AHI) have been introduced. There are no studies on their association with markers of subclinical myocardial injury. We assessed the association between novel desaturation ...
  • Harðardottir, Hronn; Jonsson, Steinn; Gunnarsson, Orvar; Hilmarsdottir, Bylgja; Asmundsson, Jurate; Gudmundsdottir, Ingibjorg; Saevarsdottir, Vaka Yr; Hansdottir, Sif; Hannesson, Petur; Gudbjartsson, Tomas (2022-01-04)
    Lungnakrabbamein er annað algengasta krabbameinið á Íslandi hjá konum og þriðja hjá körlum. Þótt hægt hafi á nýgengi sjúkdómsins á undanförnum árum dregur ekkert krabbamein fleiri Íslendinga til dauða. Einkenni lungnakrabbameins geta verið staðbundin ...
  • Barkovskaya, Anna; Seip, Kotryna; Hilmarsdóttir, Bylgja; Maelandsmo, Gunhild M; Moestue, Siver A; Itkonen, Harri M (2019-04-05)
    Post-translational modification of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the enzyme that catalyzes ...
  • Sigurdardottir, Anna Karen; Jonasdottir, Arna Steinunn; Asbjarnarson, Arni; Helgudottir, Hildur Run; Gudjonsson, Thorarinn; Traustadottir, Gunnhildur Asta (2021-12-28)
    The human breast is composed of terminal duct lobular units (TDLUs) that are surrounded by stroma. In the TDLUs, basement membrane separates the stroma from the epithelial compartment, which is divided into an inner layer of luminal epithelial cells ...